Best TWAS P=1.74e-11 · Best GWAS P=3.26e-25 conditioned to 1.26e-13
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DLEU7 | 0.05 | 0.00 | blup | 581 | 0.02 | 1.6e-03 | -1.5 | -5.3 | 1.2e-07 | -0.46 | 0.08 | 0.21 | FALSE |
| 2 | GTEx | Esophagus Mucosa | EBPL | 0.44 | 0.16 | enet | 35 | 0.24 | 2.6e-16 | 4.2 | 5.2 | 1.9e-07 | 0.00 | 0.95 | 0.04 | TRUE |
| 3 | NTR | Blood | DLEU7 | 0.07 | 0.02 | enet | 22 | 0.06 | 1.3e-19 | 5.4 | 6.7 | 1.7e-11 | 0.60 | 0.06 | 0.94 | TRUE |
| 4 | YFS | Blood | DLEU1 | 0.13 | 0.12 | lasso | 10 | 0.16 | 7.4e-49 | -5.2 | 5.4 | 7.9e-08 | -0.08 | 1.00 | 0.00 | TRUE |