TWAS
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Traits
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Impedance of leg (right)
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chr13:49,557,805-52,109,040
Best TWAS P=1.74e-11 · Best GWAS P=3.26e-25 conditioned to 1.26e-13
49.5M
50M
50.5M
51M
51.5M
52M
0
5
10
15
20
25
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
NTR
Blood
DLEU7
0.07
0.02
enet
22
0.06
1.3e-19
5.4
6.7
1.7e-11
0.60
0.06
0.94
TRUE
4
YFS
Blood
DLEU1
0.13
0.12
lasso
10
0.16
7.4e-49
-5.2
5.4
7.9e-08
-0.08
1.00
0.00
TRUE
2
GTEx
Esophagus Mucosa
EBPL
0.44
0.16
enet
35
0.24
2.6e-16
4.2
5.2
1.9e-07
0.00
0.95
0.04
TRUE
1
CommonMind
Brain Pre-frontal Cortex
DLEU7
0.05
0.00
blup
581
0.02
1.6e-03
-1.5
-5.3
1.2e-07
-0.46
0.08
0.21
FALSE