Best TWAS P=6.78e-19 · Best GWAS P=2.17e-36 conditioned to 2.66e-17
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NAPA | 0.06 | 0.00 | bslmm | 381 | 0.01 | 7.2e-03 | -1.1 | 5.6 | 1.8e-08 | 0.30 | 0.06 | 0.08 | FALSE |
| 2 | GTEx | Cells EBV-transformed lymphocytes | SAE1 | 0.21 | 0.09 | lasso | 3 | 0.07 | 2.0e-03 | 7.0 | 8.9 | 6.8e-19 | 0.77 | 0.06 | 0.67 | TRUE |
| 3 | GTEx | Thyroid | CCDC9 | 0.22 | 0.09 | lasso | 4 | 0.16 | 3.6e-12 | 2.2 | -6.4 | 1.5e-10 | -0.32 | 0.98 | 0.00 | TRUE |
| 4 | METSIM | Adipose | SAE1 | 0.12 | 0.04 | lasso | 5 | 0.07 | 1.7e-10 | 6.2 | 8.3 | 8.7e-17 | 0.61 | 0.61 | 0.39 | FALSE |
| 5 | YFS | Blood | SAE1 | 0.07 | 0.02 | enet | 18 | 0.05 | 3.6e-16 | 7.6 | 6.8 | 1.3e-11 | 0.56 | 0.99 | 0.01 | FALSE |