[Hub]/) : Traits : Impedance of leg (right) : ← →

chr22:19,262,852-20,330,744

Best TWAS P=1.23e-10 · Best GWAS P=2.07e-08 conditioned to 0.0283

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Cells Transformed fibroblasts	ZDHHC8	0.18	0.07	enet	26	0.14	8.9e-11	5.3	6.4	1.2e-10	-0.60	0.01	0.99	TRUE
1	GTEx	Artery Tibial	AC006547.14	0.09	0.00	lasso	4	0.00	6.9e-01	-4.2	6.2	4.4e-10	-0.38	0.03	0.45	FALSE
8	The Cancer Genome Atlas	Brain Lower Grade Glioma	ARVCF	0.03	0.01	blup	116	0.01	1.1e-02	4.3	5.9	3.3e-09	-0.35	0.02	0.41	FALSE
7	The Cancer Genome Atlas	Colon Adenocarcinoma	ZDHHC8	0.05	0.02	blup	73	0.04	2.6e-03	3.7	5.5	3.0e-08	-0.56	0.03	0.66	FALSE
10	The Cancer Genome Atlas	Thyroid Carcinoma	ZDHHC8	0.05	0.01	blup	73	0.02	1.0e-02	3.7	5.4	7.1e-08	-0.54	0.05	0.84	FALSE
6	GTEx	Thyroid	ARVCF	0.25	0.09	enet	39	0.20	7.5e-15	-4.2	-5.3	1.0e-07	0.11	0.61	0.35	FALSE
5	GTEx	Nerve Tibial	AC006547.14	0.15	0.06	lasso	4	0.06	4.9e-05	4.9	5.2	2.3e-07	-0.35	0.05	0.89	FALSE
9	The Cancer Genome Atlas	Thyroid Carcinoma	C22orf25	0.10	0.12	lasso	4	0.12	3.0e-11	5.0	5.1	2.7e-07	-0.52	0.02	0.98	FALSE
2	GTEx	Brain Cerebellum	ZDHHC8	0.38	0.05	lasso	10	0.04	3.2e-02	5.3	-5.1	2.9e-07	0.54	0.02	0.90	FALSE
3	GTEx	Cells Transformed fibroblasts	ARVCF	0.25	0.10	enet	23	0.16	4.3e-12	5.2	5.1	3.0e-07	-0.26	0.02	0.98	FALSE