[Hub]/) : Traits : Impedance of leg (right) : ← →

chr22:19,262,852-20,330,744

Best TWAS P=1.23e-10 · Best GWAS P=2.07e-08 conditioned to 0.0283

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial AC006547.14 0.09 0.00 lasso 4 0.00 6.9e-01 -4.2 6.2 4.4e-10 -0.38 0.03 0.45 FALSE
2 GTEx Brain Cerebellum ZDHHC8 0.38 0.05 lasso 10 0.04 3.2e-02 5.3 -5.1 2.9e-07 0.54 0.02 0.90 FALSE
3 GTEx Cells Transformed fibroblasts ARVCF 0.25 0.10 enet 23 0.16 4.3e-12 5.2 5.1 3.0e-07 -0.26 0.02 0.98 FALSE
4 GTEx Cells Transformed fibroblasts ZDHHC8 0.18 0.07 enet 26 0.14 8.9e-11 5.3 6.4 1.2e-10 -0.60 0.01 0.99 TRUE
5 GTEx Nerve Tibial AC006547.14 0.15 0.06 lasso 4 0.06 4.9e-05 4.9 5.2 2.3e-07 -0.35 0.05 0.89 FALSE
6 GTEx Thyroid ARVCF 0.25 0.09 enet 39 0.20 7.5e-15 -4.2 -5.3 1.0e-07 0.11 0.61 0.35 FALSE
7 The Cancer Genome Atlas Colon Adenocarcinoma ZDHHC8 0.05 0.02 blup 73 0.04 2.6e-03 3.7 5.5 3.0e-08 -0.56 0.03 0.66 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma ARVCF 0.03 0.01 blup 116 0.01 1.1e-02 4.3 5.9 3.3e-09 -0.35 0.02 0.41 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma C22orf25 0.10 0.12 lasso 4 0.12 3.0e-11 5.0 5.1 2.7e-07 -0.52 0.02 0.98 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma ZDHHC8 0.05 0.01 blup 73 0.02 1.0e-02 3.7 5.4 7.1e-08 -0.54 0.05 0.84 FALSE