Best TWAS P=1.12e-10 · Best GWAS P=1.03e-10 conditioned to 0.0295
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | FAM98A | 0.17 | 0.05 | enet | 17 | 0.07 | 7.3e-05 | 4.6 | -5.1 | 3.1e-07 | -0.06 | 0.68 | 0.05 | TRUE |
2 | GTEx | Artery Tibial | LTBP1 | 0.10 | 0.04 | enet | 12 | 0.03 | 1.5e-03 | -4.5 | 5.3 | 1.1e-07 | -0.84 | 0.04 | 0.95 | FALSE |
3 | GTEx | Cells Transformed fibroblasts | LTBP1 | 0.48 | 0.51 | enet | 58 | 0.51 | 2.4e-43 | -5.8 | 6.5 | 1.1e-10 | -0.93 | 0.04 | 0.96 | TRUE |