[Hub]/) : Traits : Impedance of leg (right) : ← →

chr2:26,223,547-29,260,106

Best TWAS P=2.95e-24 · Best GWAS P=7.65e-20 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SUPT7L	0.05	0.02	blup	28	0.04	5.2e-05	-8.95	-10.2	3.0e-24	-0.40	0.00	0.98	TRUE
12	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	FNDC4	0.13	0.06	lasso	2	0.05	1.1e-03	9.12	-9.7	2.2e-22	-0.99	0.00	0.96	TRUE
2	GTEx	Breast Mammary Tissue (Female)	AC074117.10	0.06	0.01	lasso	2	0.04	2.7e-02	-7.32	-8.1	8.1e-16	-0.23	0.04	0.21	TRUE
10	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	SUPT7L	0.06	0.03	blup	29	0.05	2.0e-03	-8.73	-7.2	7.1e-13	-0.04	0.01	0.83	TRUE
5	METSIM	Adipose	BRE	0.03	0.00	blup	534	0.00	1.3e-01	-0.54	5.4	6.0e-08	0.30	0.10	0.06	TRUE
7	YFS	Blood	MRPL33	0.02	0.01	blup	385	0.01	6.4e-05	-6.83	5.3	8.8e-08	0.22	0.86	0.11	TRUE
6	ROSMAP	Brain Pre-frontal Cortex	KCNK3	0.24	0.15	lasso	3	0.15	6.5e-19	-5.07	5.3	1.0e-07	0.09	0.00	0.99	TRUE
1	CommonMind	Brain Pre-frontal Cortex	SUPT7L	0.03	0.02	blup	303	0.02	1.4e-03	-2.81	-5.2	1.7e-07	-0.01	0.03	0.92	TRUE
3	GTEx	Stomach	AC074117.10	0.06	0.01	lasso	7	0.01	7.8e-02	-1.98	-9.4	4.3e-21	-0.36	0.17	0.18	FALSE
4	GTEx	Thyroid	FNDC4	0.24	0.10	enet	23	0.16	2.2e-12	-8.34	-9.3	1.3e-20	-0.69	0.73	0.27	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	FNDC4	0.24	0.09	enet	9	0.17	1.9e-16	-8.43	-9.2	4.7e-20	-0.70	0.22	0.78	FALSE
16	The Cancer Genome Atlas	Thyroid Carcinoma	IFT172	0.08	0.01	blup	43	0.02	6.1e-03	-7.83	-8.8	1.7e-18	-0.54	0.02	0.28	FALSE
15	The Cancer Genome Atlas	Thyroid Carcinoma	GCKR	0.18	0.08	enet	5	0.13	1.7e-12	-8.34	-8.7	4.4e-18	-0.64	0.35	0.65	FALSE
8	The Cancer Genome Atlas	Breast Invasive Carcinoma	GPN1	0.06	0.02	lasso	6	0.02	7.2e-05	7.59	5.9	3.8e-09	0.54	0.23	0.02	FALSE
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	SUPT7L	0.01	0.01	blup	29	0.01	1.3e-02	-0.43	-5.4	8.5e-08	0.03	0.04	0.72	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	SUPT7L	0.03	0.04	blup	29	0.03	7.2e-05	-2.81	-5.3	1.1e-07	0.07	0.08	0.84	FALSE