Hub : Genes

LTBP1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0690 0.0260 3.0e-03 0.030 0.021 0.056 0.034 0.038 1.3e-04 1.2e-03 2.1e-07 4.8e-05 1.9e-05
2 GTEx Artery Tibial 0.0954 0.0360 2.7e-03 0.044 NA 0.032 NA 0.021 2.1e-04 NA 1.5e-03 NA 8.0e-03
3 GTEx Cells Transformed fibroblasts 0.4750 0.0490 0.0e+00 0.513 NA 0.506 NA 0.464 3.5e-44 NA 2.4e-43 NA 1.5e-38
4 GTEx Liver 0.3310 0.1080 7.8e-03 0.015 NA 0.005 NA 0.068 1.2e-01 NA 2.3e-01 NA 6.1e-03
5 ROSMAP Brain Pre-frontal Cortex 0.0951 0.0263 1.2e-06 0.068 0.050 0.044 0.051 0.056 4.2e-09 4.5e-07 2.0e-06 3.3e-07 1.0e-07
6 TCGA Breast Invasive Carcinoma 0.0295 0.0134 5.8e-03 0.019 0.015 0.016 NA 0.015 5.6e-05 4.3e-04 2.3e-04 NA 2.9e-04
7 TCGA Head and Neck Squamous Cell Carcinoma 0.0734 0.0310 5.0e-03 0.003 0.009 0.004 NA 0.020 1.3e-01 2.7e-02 1.1e-01 NA 2.1e-03
8 TCGA Liver Hepatocellular Carcinoma 0.2050 0.0710 8.5e-04 0.077 0.074 0.064 NA 0.077 1.8e-04 2.3e-04 6.1e-04 NA 1.8e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.2 0.4 1.3 -0.2 0.7 0.8 -0.5 0.2 0.5 -0.1 -1.1
Bipolar Disorder or Schizophrenia 0.2 0.6 1.2 -1.1 0.1 0.5 0.9 -1.1 0.6 0.6 -0.5
Depressed Affect (Nagel 2018) 1.0 2.2 4.9 0.4 -1.7 -1.5 -2.0 -1.1 1.1 -0.8 2.2
Depression (Nagel 2018) 0.6 0.9 1.7 -0.4 -1.1 -1.1 -0.9 -1.3 -0.1 -1.2 -0.1
Intelligence (Savage-Jansen 2018) 0.5 1.4 2.6 1.6 1.6 0.6 0.9 1.4 0.9 -1.4 0.1
Neuroticism (Nagel 2018) 0.9 2.1 5.3 1.4 -1.8 -1.5 -1.2 -0.0 1.5 -0.7 2.3
Schizophrenia (2018) 0.4 0.9 2.5 -1.1 -0.4 -0.0 1.6 -1.5 0.4 0.8 0.3
Schizophrenia vs Biploar Disorder 0.9 1.2 2.7 1.4 1.4 1.3 -0.5 0.9 -0.1 1.6 0.2
Worry (Nagel 2018) 0.5 1.1 3.0 1.2 -1.0 -0.4 -0.8 0.2 1.7 -0.2 1.6
Alzheimer’s Disease (in mother) 0.2 0.3 1.0 0.3 -0.6 -0.2 0.1 0.3 -0.3 1.0 0.8
Alzheimer’s Disease (in father) 0.5 0.5 3.2 0.1 0.0 0.3 1.8 -0.5 -0.0 -0.5 0.8
Alzheimer’s Disease (including proxy) 0.5 0.7 2.1 -0.6 -0.9 -0.5 1.2 -0.8 -0.2 0.1 1.5
Crohns Disease (2017) 0.5 1.1 4.5 1.5 0.3 0.3 1.2 -0.4 0.2 -0.0 -2.1
Irritable Bowel Disease (IBD) 0.4 1.0 5.1 2.3 0.4 0.5 1.2 -0.1 0.5 -0.4 -0.9
Ulcerative Colitis (UC) 0.5 0.9 4.8 2.2 -0.1 0.2 1.1 0.3 0.6 -0.5 0.6
Major Depression (MDD) 1.0 1.2 4.0 -0.1 -1.5 -0.6 1.4 -0.6 -2.0 0.2 0.9
Reaction Time 0.3 0.6 2.4 -0.3 -0.9 0.9 0.3 -0.4 0.0 1.6 0.5
Verbal and Numeric Reasoning (VNR) 0.5 1.2 2.1 0.8 1.5 0.9 1.1 0.7 1.4 -1.1 0.9
Breast Cancer 0.4 1.0 3.6 1.3 0.4 0.4 1.9 1.1 0.9 0.2 0.7
Ovarian Cancer 0.5 0.7 2.8 -0.0 -0.8 -0.4 -0.5 -0.8 -1.7 -0.9 -0.2
Prostate Cancer 0.9 1.3 3.0 0.6 1.7 1.6 1.1 0.6 -1.0 1.3 0.5
Age at First Birth 0.7 1.0 2.2 1.5 -1.2 -0.8 1.2 -0.2 -0.7 -0.3 1.2
Bipolar Disorder (2011) 0.5 0.5 1.5 -0.1 0.3 0.6 0.2 -0.6 0.2 1.2 -1.2
Body Mass Index (BMI) (2010) 0.8 1.1 2.8 -0.3 -0.5 -1.4 0.8 -0.7 -1.4 0.8 1.7
Coronary Artery Disease (CAD) 0.9 1.1 2.8 1.7 1.5 1.4 0.5 0.5 0.0 0.8 0.5
Crohns Disease (2012) 1.1 1.7 3.2 1.8 1.8 1.0 1.1 0.3 -1.0 1.6 -1.2
Mean Putamen Volume 0.5 0.6 2.0 -0.5 -0.6 -1.4 -0.6 -0.1 0.8 -1.0 0.2
Fasting Glucose 0.2 0.3 1.0 0.5 -0.0 -0.4 -1.0 0.7 -0.5 0.5 0.1
HbA1C 1.9 2.1 5.8 0.5 2.0 2.4 1.7 -0.8 1.7 0.6 0.1
HDL Cholesterol 0.2 0.3 0.8 -0.2 -0.1 -0.5 0.9 0.1 -0.9 -0.2 0.3
LDL Cholesterol 1.2 1.9 6.2 -1.1 1.9 2.5 -0.1 -1.1 -0.3 1.7 0.3
Lupus 0.4 0.6 2.2 -1.1 0.2 -0.3 0.1 -0.2 -1.5 0.0 1.1
Neuroticism (2016) 1.1 1.6 4.0 1.9 -1.2 -1.0 -0.1 1.4 2.0 -0.5 -0.3
Primary Biliary Cirrhosis 0.4 0.6 2.2 -0.3 1.5 1.5 0.2 -0.5 0.4 0.4 -0.1
Rheumatoid Arthritis 0.8 1.2 2.5 1.6 -0.8 -0.9 0.3 1.1 1.5 -1.3 0.3
Schizophrenia (2014) 0.2 0.4 1.4 0.2 0.5 0.8 0.3 -0.4 0.5 1.2 -0.0
Triglycerides 0.1 0.2 0.3 0.6 0.5 0.3 -0.1 -0.3 0.3 -0.4 0.5
Type 2 Diabetes (T2D) (2012) 0.3 0.3 1.3 0.0 -0.6 -0.6 0.3 -0.7 -1.1 0.2 -0.1
Ulcerative Colitis 1.1 1.6 7.4 2.7 0.7 0.6 1.3 1.5 0.1 -0.4 0.2
Blood Eosinophil Count 0.1 0.9 6.1 1.1 0.2 0.2 0.1 0.3 -0.3 -0.1 2.5
Blood Platelet Count 0.4 4.8 11.7 -2.0 -0.1 -0.4 2.6 -2.9 -2.7 -0.4 3.4
Blood Red Count 0.4 3.8 18.8 0.5 -2.6 -2.0 0.7 -0.4 -0.4 -4.3 0.2
Blood White Count 0.1 0.8 2.4 -1.1 -0.1 0.8 -0.9 -1.6 0.7 0.5 0.8
Heel T-Score 0.3 2.1 6.8 -2.0 -1.1 -0.9 -0.5 -1.2 -0.3 -1.5 2.6
BMI 1.2 6.8 18.2 -2.1 -4.3 -4.0 1.2 -2.3 -0.9 -1.2 2.6
Height 2.2 41.5 130.0 4.2 10.2 11.4 -2.3 0.4 -0.0 0.7 -8.6
Waist Hip Ratio (WHR) 1.0 4.3 13.5 -0.4 3.0 3.7 -2.5 -0.5 1.9 1.0 -1.0
Systolic Blood Pressure 0.1 0.7 2.4 0.5 1.6 0.7 -0.8 0.1 0.9 -0.3 -1.1
Smoking Status 0.7 1.6 4.5 -1.1 -1.5 -1.3 0.4 -2.1 0.9 -1.2 -0.4
Allergy or Eczema 0.7 1.9 3.6 1.9 1.9 1.7 -0.7 1.7 0.7 1.2 0.5
Cardiovascular Disease 0.2 0.6 1.4 0.1 0.7 0.7 -1.2 0.4 -0.0 -1.0 -1.0
Hypothyroidism (self reported) 0.8 1.8 5.9 -0.5 -1.7 -1.8 2.4 0.1 0.5 -1.5 -0.0
Respiratory disease 0.7 1.5 3.6 1.9 1.1 0.4 1.2 0.8 0.7 -1.1 1.8
Type 2 Diabetes (T2D) (2018) 0.2 0.4 1.7 -0.6 0.2 -0.1 -0.5 -1.3 -0.2 0.5 -0.6
Lung FEV1/FVC ratio 2.2 11.4 26.1 -5.1 2.6 3.7 -2.5 -3.8 -1.8 4.1 -2.0
Lung FVC 2.0 10.2 33.5 0.5 -4.9 -5.8 2.4 0.8 -1.6 -3.8 0.6
Neuroticism 0.5 1.2 3.8 1.0 -0.4 -0.2 -1.6 0.1 2.0 0.3 1.3
Chronotype (morning person) 0.5 1.2 4.9 1.9 -0.1 -0.0 0.0 2.2 -0.6 -0.5 0.4
Hair Pigment 0.1 2.1 6.4 -2.5 -1.0 -0.1 1.8 -1.3 -1.4 -0.7 -1.5
Tanning 0.3 3.1 13.5 -3.0 -0.4 0.3 -0.1 -3.7 1.1 0.8 -0.1
Hand grip strength (left) 0.8 2.1 7.0 1.1 2.6 2.1 -1.3 1.0 0.4 0.7 -0.5
Number of treatments/medications taken 0.4 0.7 1.3 1.0 -0.9 -0.7 0.9 0.6 1.0 -1.1 0.3
Average weekly spirits intake 0.7 0.9 2.2 -1.0 0.8 1.3 0.1 -1.5 1.2 0.0 -0.3
Sensitivity / hurt feelings 1.7 2.9 9.2 3.0 -0.5 -0.8 -0.7 2.8 1.2 -0.6 1.7
Frequency of depressed mood in last 2 weeks 0.4 0.5 1.2 0.3 -0.4 -0.8 -1.1 -0.7 0.1 -0.9 1.0
Hearing difficulty/problems: Yes 0.6 0.9 2.9 1.7 -0.7 -1.3 0.8 0.9 -0.4 0.1 0.4
Relative age of first facial hair 1.1 2.2 9.8 1.3 -1.0 -1.4 -0.2 3.1 0.1 -1.7 -0.5
Other serious medical condition/disability diagnosed by doctor 0.5 0.7 2.0 -1.0 0.5 0.3 0.6 -0.4 -0.9 -1.4 0.7
Ever used hormone-replacement therapy (HRT) 0.9 1.1 2.5 -1.0 -1.6 -1.0 -0.8 -1.5 0.8 -0.7 0.5
Ever had hysterectomy (womb removed) 0.7 0.8 3.3 0.7 -1.8 -1.3 0.6 -0.0 -0.1 -0.9 0.2
Systolic blood pressure, automated reading 0.1 0.3 1.0 -0.3 0.3 -0.6 -0.1 -1.0 -0.8 -0.3 0.3
Eye problems/disorders: Diabetes related eye disease 0.7 0.8 2.2 -0.2 -1.5 -1.0 -1.3 0.3 -1.2 0.2 0.4
Angina 0.8 1.0 2.5 0.8 0.7 0.6 -1.3 1.6 -0.6 0.4 1.5
Medication for hormone replacement therapy 0.6 0.6 2.5 -0.1 0.1 1.6 -0.7 -0.2 0.5 0.6 -1.2
Vitamin and mineral supplements 0.3 0.5 1.0 0.6 0.9 1.0 -0.2 0.5 -1.0 0.3 -0.3
Supplements: Zinc 0.7 0.7 2.6 -0.4 0.7 1.2 1.6 0.4 1.0 -0.2 -0.1
Medication: Co-codamol 0.6 0.7 1.9 0.4 -1.3 -0.8 -0.1 -0.5 -0.9 1.4 -0.7
Medication: Metformin 0.6 0.8 3.4 -0.6 0.7 -0.2 -1.9 -1.2 0.3 0.7 -0.6
Diabetes (father) 0.7 0.8 2.3 1.0 -1.1 -1.5 0.2 -0.1 -0.6 -1.2 -0.4
Diabetes (mother) 1.1 1.4 3.9 -0.8 1.4 1.7 0.8 -0.6 0.6 2.0 0.5
Severe depression (siblings) 0.2 0.2 0.8 -0.4 -0.8 0.2 -0.1 -0.0 -0.3 0.9 0.1
Pack years adult smoking proportion 0.4 0.6 1.5 -0.8 -0.1 0.2 -1.2 -0.8 1.2 -0.2 -0.6
Impedance of leg (right) 2.4 11.4 41.6 0.3 5.3 6.5 -3.6 0.2 0.4 2.5 -1.5
Leg fat-free mass (left) 0.2 1.0 5.5 -0.6 -0.3 -0.3 -0.2 -1.0 0.1 -0.9 -2.3
Trunk fat percentage 0.2 1.0 3.6 -1.2 -0.1 0.3 -1.1 -1.9 -0.3 -0.3 1.1
Hand grip strength (right) 0.7 2.0 7.3 1.3 2.7 2.0 -0.6 1.4 0.4 0.5 -0.2
Townsend deprivation index at recruitment 0.5 0.7 1.5 0.7 -0.1 -0.4 0.7 0.2 1.1 -1.1 1.2
Current tobacco smoking 1.1 1.8 5.6 -2.0 -1.7 -1.1 0.2 -2.4 0.8 0.2 -0.3
Average weekly fortified wine intake 1.4 1.7 6.7 -2.6 0.9 0.9 -0.4 -2.1 0.0 0.7 0.5
Maternal smoking around birth 0.6 0.8 1.4 0.6 -1.2 -1.1 -0.0 1.0 -1.1 -1.2 0.4
Fed-up feelings 0.7 1.3 3.6 1.3 -0.5 -0.2 -1.7 0.1 1.9 -0.1 1.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.7 0.9 2.6 -0.4 -1.6 -0.7 -1.5 -0.5 0.7 -1.0 0.0
Relative age voice broke 0.9 1.4 7.0 1.7 0.3 -0.2 -0.3 2.6 0.1 -0.7 0.4
Taking other prescription medications 0.4 0.7 1.3 1.1 -0.8 -0.9 1.1 0.2 -0.9 -0.5 0.4
Age when periods started (menarche) 0.4 1.0 3.2 0.4 -1.4 -1.3 -0.4 0.8 -0.1 -0.6 -1.8
Bilateral oophorectomy (both ovaries removed) 0.5 0.6 3.0 -0.8 -0.6 0.0 -0.4 -1.7 0.9 0.0 -0.0
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.4 1.5 -0.8 0.5 0.0 -0.5 0.3 -0.3 -0.6 1.2
Tinnitus: Yes, but not now, but have in the past 0.2 0.3 1.0 0.4 0.8 -0.0 1.0 0.2 -0.5 0.2 0.2
Qualifications: CSEs or equivalent 0.6 0.8 2.7 -0.7 0.6 1.4 -1.6 -0.1 0.7 0.7 0.0
Serious illness, injury or assault to yourself 0.9 1.1 2.6 1.3 0.2 -0.9 -0.5 1.0 -0.5 -1.5 1.6
High blood pressure 0.3 0.7 2.2 0.2 -1.0 -0.9 0.4 0.6 0.3 -1.5 1.1
Hayfever, allergic rhinitis or eczema 0.3 0.7 1.5 0.7 1.2 1.2 -1.0 0.7 0.6 0.6 0.4
Multivitamins +/- minerals 0.5 0.6 1.3 -1.0 -0.8 -0.7 0.4 -1.0 0.3 0.1 1.2
Stomach or abdominal pain in last month 0.9 1.1 4.1 0.5 -0.5 0.5 -1.2 0.4 2.0 1.2 -1.0
Supplements: Glucosamine 0.3 0.3 1.2 -0.3 -1.1 -0.8 0.2 0.3 0.0 -0.7 -0.4
Diverticular disease/diverticulitis (self-reported) 0.3 0.4 1.1 -0.6 0.7 0.2 -0.8 -0.3 0.6 1.0 -0.3
Medication: Atenolol 1.3 1.6 4.2 2.0 -0.2 -0.9 1.0 2.0 0.3 -1.1 1.3
Medication: Levothyroxine sodium 1.5 2.6 10.1 0.5 -2.1 -2.0 3.2 -0.2 -0.2 -1.3 0.2
Sitting height 1.9 13.2 31.0 3.3 5.5 5.6 -0.9 2.2 0.7 -0.1 -5.2
Chronic bronchitis/emphysema (father) 1.5 1.8 5.2 -2.1 -0.7 -1.4 -0.7 -2.3 -0.5 -1.2 0.4
High blood pressure (mother) 1.2 1.7 5.4 2.3 -0.7 -1.6 1.9 0.6 0.4 -0.6 1.0
Body mass index (BMI) 1.1 4.8 13.3 -1.9 -3.5 -3.6 0.5 -1.9 -0.2 -0.7 2.2
Impedance of leg (left) 2.3 11.3 41.5 0.6 5.3 6.4 -3.9 0.6 -0.0 1.8 -1.0
Leg predicted mass (left) 0.2 0.9 5.3 -0.5 -0.2 -0.2 -0.1 -0.9 0.1 -0.8 -2.3
Trunk fat mass 0.2 1.0 3.9 -1.2 0.4 0.7 -1.3 -2.0 -0.2 -0.4 0.1
Waist circumference 0.3 1.0 3.9 -1.2 -0.6 -0.6 -0.6 -2.0 0.8 -0.7 -0.1
Number of incorrect matches in round 0.2 0.4 1.0 -0.5 -0.4 -1.0 0.2 0.3 0.9 0.8 -0.1
Past tobacco smoking 0.6 1.1 2.9 0.8 0.8 1.2 -0.3 1.4 -0.8 1.7 0.6
Alcohol usually taken with meals 0.7 1.1 2.2 -0.9 1.3 1.5 -1.1 -0.2 -1.4 0.5 -0.7
Nervous feelings 0.5 0.9 3.8 0.2 -1.4 -0.7 -0.7 0.6 0.5 -0.4 1.9
Frequency of tenseness / restlessness in last 2 weeks 1.6 2.4 7.0 -0.4 -2.1 -1.5 -1.3 -1.1 1.0 -2.6 1.4
Hearing difficulty/problems with background noise 1.1 1.7 6.1 2.5 0.1 -0.6 0.3 1.8 1.2 -1.0 1.0
Hair/balding pattern: Pattern 2 1.2 1.5 6.4 0.3 0.9 0.7 -1.5 -0.5 1.1 -0.6 -2.5
Had menopause 0.5 0.6 1.5 -0.5 -1.0 -0.2 -0.0 -1.2 -1.2 -0.3 -0.7
Had other major operations 0.4 0.4 1.8 0.3 -0.6 -0.4 0.3 0.1 -0.3 -1.3 -0.9
Forced vital capacity (FVC) 0.6 2.4 10.3 1.1 0.7 0.4 0.3 0.9 -1.4 -2.0 -3.2
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.9 2.3 -1.2 1.2 1.0 -1.5 -0.4 -0.4 0.0 0.4
Ever unenthusiastic/disinterested for a whole week 0.7 0.8 3.0 0.8 -0.6 -0.8 1.7 -0.7 0.0 -1.1 0.7
Qualifications: None of the above 0.7 1.4 3.5 0.2 -1.9 -1.5 -0.2 -1.4 1.9 -0.2 -0.1
Financial difficulties in last 2 years 0.9 1.2 4.7 1.0 -0.2 0.2 -1.0 1.6 2.2 0.5 0.4
Mouth/teeth dental problems 1.1 1.7 7.4 -0.5 1.0 1.2 2.7 0.2 0.0 1.7 -0.5
Heart attack 0.4 0.5 1.3 1.1 0.7 0.8 0.3 -0.4 -0.6 -0.4 0.9
Allergy 0.1 0.3 0.9 -0.4 -1.0 -0.6 0.7 0.2 -0.1 0.4 -0.1
Pain all over the body in last month 0.9 1.0 3.4 0.5 -0.8 -0.7 1.4 -0.1 -0.1 -1.1 1.8
Diabetes (self-reported) 0.4 0.7 1.8 -0.4 1.1 0.6 -0.9 -0.9 0.1 1.3 -0.6
Hayfever/allergic rhinitis (self-reported) 0.3 0.3 1.9 -0.2 -0.2 -0.2 -0.0 0.1 0.6 -1.4 0.6
Medication: Ramipril 1.4 1.8 5.5 1.1 0.4 0.5 0.6 0.5 2.3 1.0 2.3
Medication: Simvastatin 0.6 0.8 2.0 0.3 -0.5 -0.9 -1.4 -0.6 1.1 -1.3 -0.1
Fluid intelligence score 0.6 1.3 3.8 1.2 0.1 -0.6 1.1 1.3 1.9 -1.0 1.1
Illnesses of siblings 0.4 0.6 1.3 -0.9 -0.7 -0.3 0.3 -1.1 0.7 -0.0 1.1
Neuroticism score 1.1 2.2 5.9 1.8 -1.6 -1.2 -1.5 0.6 1.3 -0.7 2.4
Weight 0.1 0.7 2.6 -0.8 0.4 0.5 -0.9 -1.6 -0.1 -0.6 -1.0
Impedance of arm (right) 1.1 5.0 19.3 1.5 3.3 4.4 -2.3 0.5 -0.3 0.9 -1.0
Arm fat percentage (right) 0.6 2.3 4.8 -1.5 -2.2 -1.8 -0.5 -2.2 -0.1 -0.1 1.7
Trunk fat-free mass 0.5 2.6 12.7 -0.3 1.8 1.7 -0.7 -1.1 0.2 -0.6 -3.6
Hip circumference 0.3 1.2 4.5 -1.1 -0.9 -1.1 -0.1 -2.1 -0.2 -1.3 -0.6
Time employed in main current job 0.3 0.3 1.5 0.4 1.2 0.5 -0.4 0.1 -0.2 0.5 0.6
Alcohol intake versus 10 years previously 0.6 0.9 2.5 0.8 -1.6 -1.2 0.2 1.1 0.9 0.7 0.7
Father’s age at death 0.5 0.7 3.3 0.5 0.9 0.6 0.5 0.4 -1.8 -0.2 0.8
Worrier / anxious feelings 0.1 0.2 0.7 0.7 -0.3 0.1 0.5 0.2 0.5 0.2 0.8
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.8 2.3 -0.3 -0.5 0.2 -1.5 -1.2 1.4 -0.6 0.6
Falls in the last year 0.3 0.4 1.6 -0.3 -0.4 0.8 -1.2 0.1 0.3 -0.3 0.7
Hair/balding pattern: Pattern 3 2.0 3.0 11.0 -1.8 1.1 1.6 1.1 -3.3 0.3 1.7 1.4
Number of live births 0.3 0.5 1.5 0.6 0.4 0.8 -0.2 -0.7 -1.2 -0.2 0.7
Forced expiratory volume in 1-second (FEV1) 0.8 2.7 11.1 0.5 1.8 1.8 0.0 1.0 -1.8 0.2 -3.3
Pulse rate 0.2 0.3 1.3 -0.3 -1.2 -0.7 0.3 0.1 -0.2 -0.5 0.3
Happiness 0.3 0.3 1.5 0.4 -0.3 0.1 -0.4 0.0 1.2 -0.6 0.4
Noisy workplace 1.3 1.6 3.8 -1.8 -0.7 -0.4 -1.5 -1.1 1.0 -0.4 -2.0
Qualifications: A levels/AS levels or equivalent 1.2 2.7 13.6 1.8 1.1 0.5 0.3 3.7 -1.0 -0.8 -1.2
Serious illness, injury or assault of a close relative in last 2 years 1.5 1.7 5.6 2.4 0.6 0.4 -0.3 2.1 0.9 1.4 -0.7
Mouth/teeth dental problems: Dentures 0.6 1.1 3.3 0.9 1.3 0.8 -1.8 0.3 0.9 -0.1 1.2
Asthma 0.2 0.4 1.3 0.4 0.9 -0.0 -0.7 -0.1 1.1 -0.9 0.0
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.7 2.5 0.7 -0.9 -0.3 0.1 0.2 1.6 1.0 0.6
Medication: Cholesterol lowering 0.3 0.5 1.2 -0.8 0.7 -0.3 -1.1 -0.9 -0.2 -0.7 -0.1
Depression (self-reported) 1.3 1.5 5.0 2.2 -1.4 -0.5 0.4 1.9 1.0 0.1 0.5
Medication: Lansoprazole 1.1 1.2 3.0 1.7 -1.3 -1.2 0.3 0.4 0.0 -1.7 0.6
Prospective memory result 1.3 1.6 4.3 1.4 -1.2 -1.0 1.1 -0.6 -1.6 -0.1 2.1
Lung cancer (father) 0.4 0.5 1.7 -0.6 -0.3 -0.6 -1.3 -0.8 0.1 0.1 -0.7
Illnesses of mother 2.2 2.7 7.5 -1.4 1.4 2.3 -2.7 -0.9 -1.4 0.8 -1.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.8 2.6 9.2 0.4 2.2 2.3 -0.2 0.8 -1.0 -0.1 -3.0
Pulse wave Arterial Stiffness index 0.9 1.0 2.6 -0.6 1.0 0.7 -1.2 -1.6 -1.1 0.8 -0.8
Impedance of arm (left) 1.0 4.8 19.4 1.6 3.2 4.4 -2.2 0.6 0.4 0.9 -0.3
Arm fat mass (right) 0.3 1.3 4.5 -1.5 -1.3 -1.0 -0.7 -2.1 0.2 -0.3 0.7
Trunk predicted mass 0.5 2.8 13.1 -0.4 1.9 1.8 -0.7 -1.1 0.2 -0.5 -3.6
Standing height 2.6 25.8 75.5 2.2 8.2 8.7 -3.4 0.4 0.1 -0.3 -6.9
Length of working week for main job 0.5 0.6 2.2 0.1 -0.7 -0.4 -1.1 0.2 -0.6 -0.4 -1.5
Exposure to tobacco smoke at home 1.0 1.1 5.2 0.5 1.0 -0.5 -0.6 1.1 0.5 2.3 -0.5
Breastfed as a baby 1.9 2.4 4.4 -2.1 1.2 2.1 0.2 -0.7 0.8 1.9 -2.1
Tense / ‘highly strung’ 1.0 1.7 3.9 1.1 -2.0 -0.7 -1.3 0.9 1.8 -0.9 1.1
Seen doctor (GP) for nerves, anxiety, tension or depression 1.6 2.5 8.1 1.6 -2.8 -1.9 1.0 0.6 1.5 -0.1 1.3
Hair/balding pattern: Pattern 4 1.2 2.9 8.4 -2.9 0.5 0.0 -0.9 -2.5 -2.2 1.1 1.1
Birth weight of first child 0.6 1.1 3.2 0.2 0.1 0.2 -1.8 0.4 0.3 1.5 -1.7
Peak expiratory flow (PEF) 1.6 3.7 11.4 -0.8 3.4 2.6 -1.0 1.5 -0.4 0.3 -2.7
Pulse wave reflection index 0.3 0.4 1.9 -0.7 0.4 0.3 0.3 -0.5 -0.6 1.4 -0.2
Ever highly irritable/argumentative for 2 days 0.8 0.9 2.4 1.2 -0.6 -0.8 -0.1 0.6 1.5 -0.9 1.3
Loud music exposure frequency 1.3 1.4 3.3 -1.3 -1.4 -0.8 0.7 -1.5 1.8 -0.1 -1.1
Qualifications: O levels/GCSEs or equivalent 1.3 2.1 7.3 1.1 0.6 0.0 1.7 2.1 -2.7 0.1 -0.7
Mouth/teeth dental problems: Bleeding gums 1.6 2.1 5.4 -0.5 -2.1 -2.3 0.1 -1.2 0.6 -1.9 1.0
Blood clot in the leg (DVT) 0.4 0.6 1.5 -0.3 0.3 0.7 -1.0 0.3 0.9 1.2 -0.6
Medication: Paracetamol 0.4 0.7 1.7 -1.3 -1.1 -0.5 -0.7 -0.8 1.0 0.5 -0.2
Headache pain in last month 1.0 1.7 7.2 -0.1 -2.7 -2.3 -0.6 -0.6 0.3 -0.3 0.5
Medication for cholesterol, blood pressure or diabetes 0.2 0.3 1.9 -0.3 -0.8 -0.1 -0.1 0.1 -0.2 1.4 -0.2
Glaucoma (self-reported) 0.4 0.5 1.3 1.1 0.3 0.4 -0.4 1.1 -0.8 -0.2 -0.2
Gout (self-reported) 0.8 1.0 2.3 1.4 0.8 1.1 0.8 1.5 0.7 0.9 0.7
Hypothyroidism/myxoedema (self-reported) 1.0 2.0 10.3 1.3 -1.2 -1.4 3.2 0.6 -0.2 -0.4 -0.2
Medication: Amlodipine 0.8 1.2 3.8 0.3 -1.2 -1.2 1.1 -0.3 0.1 -1.9 1.1
Medication: Ventolin 100micrograms inhaler 1.3 1.6 6.3 -0.5 2.3 2.5 0.7 -0.6 -0.4 0.5 -0.3
Birth weight 0.2 0.4 2.0 -0.5 0.5 0.1 0.1 -0.7 0.4 0.2 -1.4
Chronic bronchitis/emphysema (mother) 2.8 3.3 10.5 0.2 -3.2 -2.2 0.7 -0.1 0.0 -3.2 -0.6
High blood pressure (siblings) 0.7 1.1 4.1 2.0 0.8 0.3 0.6 1.6 -0.6 -0.4 -0.2
Forced vital capacity (FVC), Best measure 0.6 2.2 8.0 1.6 1.5 1.2 0.4 1.2 -0.5 -1.3 -2.8
Body fat percentage 0.3 1.3 4.1 -1.5 -0.6 -0.3 -1.4 -2.0 -0.0 -0.0 1.4
Leg fat percentage (right) 0.6 2.1 5.5 -2.3 -0.4 -0.2 -1.6 -2.3 0.4 1.0 1.6
Arm fat-free mass (right) 0.3 1.4 7.0 -0.9 1.1 0.8 -0.2 -1.2 -0.4 -0.7 -2.6
Exposure to tobacco smoke outside home 0.2 0.2 0.7 -0.1 -0.8 -0.9 -0.4 -0.5 0.2 -0.2 0.0
Comparative body size at age 10 1.7 4.7 10.6 -2.7 -3.2 -2.7 1.7 -2.3 1.3 -0.5 1.4
Number of full brothers 1.0 1.3 4.4 -1.2 0.8 0.6 0.4 -0.9 -0.6 1.6 -2.1
Worry too long after embarrassment 1.2 1.9 5.8 1.8 -0.5 -1.1 0.8 1.3 1.7 0.2 2.4
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 1.5 1.2 -0.3 -0.2 -0.9 0.6 0.7 0.3 0.3
Wheeze or whistling in the chest in last year 0.5 1.0 3.0 -0.3 -0.2 -0.1 -0.1 -1.3 1.4 -1.7 1.0
Number of children fathered 0.4 0.4 1.2 1.1 0.3 -0.2 0.6 1.0 0.5 -0.6 0.2
Reason for reducing amount of alcohol drunk: Health precaution 0.9 1.0 2.6 -1.2 1.6 1.6 0.3 -1.2 -0.2 0.3 0.2
Age at first live birth 0.6 1.1 2.4 0.6 1.1 0.8 0.8 1.2 -0.4 1.5 -1.5
Pulse wave peak to peak time 0.6 0.7 2.1 0.6 -0.4 -0.2 1.0 1.5 1.1 -0.8 0.3
Health satisfaction 0.6 0.8 2.4 -0.5 -1.5 -0.7 0.8 -1.0 0.7 -0.0 1.0
Shortness of breath walking on level ground 0.4 0.5 1.9 0.2 -0.5 -1.0 0.3 -0.4 1.4 -0.4 -0.1
Qualifications: College or University degree 0.4 1.1 4.0 -0.5 2.0 1.7 -0.6 0.3 -1.0 -0.5 -0.5
Eye problems/disorders: None of the above 1.1 1.3 4.5 -2.1 0.8 0.2 1.2 -1.6 0.8 0.8 0.5
Mouth/teeth dental problems: Loose teeth 0.1 0.1 0.5 -0.2 0.0 -0.1 0.2 -0.1 0.4 0.1 -0.7
Emphysema/chronic bronchitis 0.9 1.0 3.4 -0.3 -1.3 -1.2 0.5 -1.9 -0.7 -0.3 0.7
Medication for pain relief, constipation, heartburn 0.6 1.0 4.0 -0.1 1.6 2.0 0.1 0.9 -0.5 0.6 0.3
Neck or shoulder pain in last month 0.2 0.3 0.6 0.2 0.6 0.6 0.8 -0.5 0.7 0.7 -0.1
Medication: Blood pressure 0.3 0.6 2.3 0.8 0.2 0.1 0.2 0.6 1.0 -1.5 0.3
Angina (self-reported) 0.7 1.0 2.2 0.7 0.7 0.7 -1.2 1.4 -0.7 0.4 1.5
Migraine (self-reported) 1.1 1.4 3.7 0.6 -1.4 -1.3 1.1 0.2 0.2 1.5 1.9
Medication: Ibuprofen 0.5 0.6 1.7 0.8 -0.7 -0.3 0.5 0.8 1.3 1.0 0.2
Medication: Allopurinol 0.5 0.7 1.5 1.2 0.5 1.0 -0.3 1.1 -0.2 0.1 1.1
Medication: Omeprazole 0.4 0.4 1.6 -0.4 0.2 0.0 0.1 -1.3 -0.7 -0.7 -0.9
Medication: Seretide 50 evohaler 0.7 0.9 2.8 1.0 1.2 0.8 0.2 0.7 0.4 -1.7 0.6
Mean time to correctly identify matches 0.3 0.6 1.8 0.9 -0.0 1.3 0.5 0.2 0.5 1.1 0.7
Heart disease (mother) 0.9 1.1 3.5 -0.8 -1.2 -1.9 1.1 -0.3 0.9 -0.3 1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.3 0.3 1.1 0.2 0.6 0.6 0.3 0.6 0.3 1.0 -0.0
Whole body fat mass 0.2 1.0 3.9 -1.5 0.1 0.2 -1.4 -2.0 0.0 -0.2 0.1
Leg fat mass (right) 0.3 1.3 3.8 -1.8 -0.2 -0.2 -1.6 -1.9 0.3 0.4 0.2
Arm predicted mass (right) 0.3 1.5 6.4 -1.0 1.2 1.0 -0.2 -1.3 -0.1 -0.4 -2.5
Pulse rate, automated reading 0.3 0.8 2.1 0.3 -1.0 -0.6 0.3 -0.8 0.5 -1.4 1.4
Alcohol intake frequency. 0.3 0.6 1.5 1.2 -0.4 -0.5 -0.5 0.9 -0.5 1.1 0.4
Comparative height size at age 10 1.3 6.9 17.9 1.7 3.8 4.2 -1.5 0.5 -0.8 -1.4 -3.9
Number of full sisters 0.3 0.3 0.6 0.5 -0.7 0.1 -0.6 0.5 0.6 0.8 0.2
Suffer from ‘nerves’ 1.8 2.8 5.8 1.8 -2.0 -0.6 -1.5 1.5 2.0 -0.9 2.4
Overall health rating 0.6 1.2 3.9 -0.5 -2.0 -0.8 -0.1 -1.9 -0.5 0.4 0.7
Chest pain or discomfort 0.7 1.0 2.0 1.0 -1.4 -1.1 -1.4 0.6 0.2 0.2 1.4
Had major operations 0.6 0.7 2.5 0.1 0.4 -0.7 1.4 -0.7 -0.3 -0.4 1.6
Age at last live birth 0.8 1.2 3.8 0.4 1.4 0.8 -0.3 0.9 -0.6 1.4 -1.9
Family relationship satisfaction 0.5 0.6 1.7 0.1 0.4 1.3 -1.1 -0.2 1.0 -0.0 -0.7
Leg pain on walking 2.3 2.9 8.1 -1.1 -2.8 -2.0 0.6 -2.4 0.9 -1.5 1.1
Qualifications: NVQ or HND or HNC or equivalent 0.7 0.8 2.2 -1.5 -0.7 -0.9 0.2 -1.0 1.5 -0.1 -0.2
Commuting to job workplace: Car/motor vehicle 0.8 1.0 5.7 -0.0 1.2 0.4 0.4 -0.4 0.1 0.4 2.4
Illness, injury, bereavement, stress in last 2 years 1.3 1.6 4.9 -1.6 0.1 0.2 -0.2 -1.8 -2.2 -0.3 -1.3
Medication: Aspirin 0.4 0.5 2.6 0.0 -0.2 -0.5 -1.6 -0.7 -0.4 -0.7 -0.1
Supplements: Vitamin C 0.4 0.5 1.1 0.4 -0.8 -0.7 1.1 0.7 0.6 -0.2 0.7
Knee pain experienced in last month 2.9 4.5 15.4 -0.6 -3.7 -3.9 2.0 -0.3 -1.2 -1.1 0.3
Hypertension (Self-reported) 0.2 0.6 2.4 -0.2 -0.9 -0.9 0.3 0.2 -0.0 -1.5 0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.8 1.0 2.3 0.0 -1.2 -1.0 0.3 -1.5 0.7 -1.3 1.0
Illnesses of father: Heart disease 0.6 0.8 3.1 0.5 -0.8 -0.5 -0.7 0.9 -0.5 1.8 0.7
Illnesses of siblings: Diabetes 0.4 0.5 1.4 0.0 0.5 0.7 -1.0 0.5 0.3 1.2 0.8
Smoking status: Previous 0.7 1.1 4.6 0.1 -0.5 -1.3 0.4 -0.7 0.9 -2.1 -0.9
Forced expiratory volume in 1-second (FEV1), predicted 5.0 10.3 25.7 -0.4 5.0 5.1 -3.4 0.2 0.6 0.8 -4.4
Whole body fat-free mass 0.3 1.6 9.4 -0.4 1.0 0.9 -0.3 -1.0 0.0 -0.7 -3.1
Leg fat-free mass (right) 0.2 1.0 5.2 -0.3 -0.4 -0.6 0.1 -0.6 -0.2 -1.4 -2.3
Arm fat percentage (left) 0.6 2.5 5.6 -1.4 -2.4 -1.9 -0.5 -2.0 0.0 -0.1 2.1
Average weekly red wine intake 0.2 0.3 1.0 -0.4 0.2 -0.5 0.5 -0.3 0.5 -1.0 -0.2
Handedness (chirality/laterality): Left-handed 0.3 0.3 1.0 -1.0 0.7 0.8 0.1 0.0 -0.1 0.4 0.3
Mood swings 0.9 1.6 6.1 1.4 -1.0 -1.1 -0.5 -0.3 0.9 -1.0 2.5
Loneliness, isolation 1.3 1.8 5.3 -1.1 -1.8 -1.1 -2.3 -1.4 -0.6 -0.9 -0.3
Long-standing illness, disability or infirmity 0.4 0.6 2.7 -0.6 -0.8 -0.4 0.2 -0.8 -0.3 -1.6 0.7
Ever had bowel cancer screening 1.2 1.4 4.6 0.1 -1.2 -2.1 -0.3 0.1 -2.1 -0.5 0.4
Diabetes diagnosed by doctor 0.4 0.6 1.8 -0.3 0.4 -0.3 -1.1 -0.5 -0.2 1.4 -1.0
Ever had stillbirth, spontaneous miscarriage or termination 0.8 0.8 3.0 0.5 -0.4 0.1 -1.7 -0.0 0.6 0.9 -1.4
Friendships satisfaction 0.7 0.9 3.6 -1.1 -0.3 0.5 -1.2 -1.9 -0.2 0.2 -0.7
Qualifications: nursing, teaching 0.3 0.4 1.2 0.4 1.1 1.1 0.2 0.4 -0.1 -0.9 -0.2
Commuting to job workplace: Walk 0.2 0.2 0.5 0.7 -0.6 0.2 0.7 0.2 -0.3 0.1 0.1
Eye problems/disorders: Cataract 0.8 0.9 3.0 1.7 -1.1 -1.1 -0.2 0.8 0.1 -0.9 0.1
Mouth/teeth dental problems: Mouth ulcers 0.6 0.9 2.4 0.3 1.6 1.0 -1.3 -0.6 0.5 -0.5 -1.2
Medication for cholesterol 0.2 0.3 0.7 -0.7 0.8 -0.1 0.1 -0.7 -0.8 0.0 0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.5 2.0 -0.7 -0.2 -0.4 0.6 -0.4 0.0 -0.9 -1.4
Back pain experienced in last month 1.6 2.4 12.3 0.6 1.0 1.9 -0.7 0.7 3.5 -0.6 -0.6
Mineral and other dietary supplements 0.6 0.8 2.6 -0.1 1.6 1.0 0.2 -1.5 -0.1 0.4 -0.2
Breast cancer (self-reported) 0.7 0.9 2.8 1.0 0.9 0.7 1.0 0.7 0.5 -0.0 -1.7
Asthma (self-reported) 0.1 0.3 0.7 0.5 0.7 -0.1 -0.4 -0.0 0.8 -0.7 0.1
Osteoporosis (self-reported) 0.8 1.0 2.5 1.5 1.6 1.1 1.0 -0.1 1.0 -0.1 -0.2
Osteoarthritis (self-reported) 2.4 3.1 10.3 -0.0 -3.2 -3.2 1.4 1.1 -0.7 -0.9 0.4
Medication: Aspirin 0.4 0.5 1.8 0.1 -0.4 -0.6 -1.3 -0.6 -0.5 -1.1 0.0
Medication: Gliclazide 0.5 0.6 1.5 -1.0 0.6 0.2 -0.8 -1.2 0.7 0.9 -0.5
Illnesses of father: None of the above (group 1) 0.7 0.9 3.9 -0.4 -0.2 0.2 -1.5 0.3 -0.2 -0.7 -2.0
Smoking status: Current 1.0 1.6 4.5 -1.7 -1.7 -1.1 0.3 -2.1 0.8 -0.0 -0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.7 2.8 -0.4 0.8 -0.1 0.3 -0.1 -1.7 1.0 0.9
Whole body water mass 0.3 1.5 8.6 -0.5 0.9 0.8 -0.2 -1.1 -0.0 -0.7 -2.9
Leg predicted mass (right) 0.2 1.0 5.3 -0.2 -0.5 -0.6 0.1 -0.6 -0.1 -1.3 -2.3
Arm fat mass (left) 0.3 1.2 3.6 -1.2 -1.3 -1.0 -0.6 -1.9 0.1 -0.2 1.0
Number of self-reported non-cancer illnesses 1.4 2.4 5.6 2.3 -1.2 -1.3 1.3 1.2 2.4 -1.3 0.6
Average weekly champagne plus white wine intake 0.5 0.7 1.8 1.4 -0.1 0.2 1.0 1.0 -1.1 -0.5 0.7
Miserableness 0.5 0.9 1.9 1.1 -1.0 -0.8 -1.3 0.7 -0.1 -0.8 1.4
Guilty feelings 1.1 1.7 5.6 -1.9 -0.6 -0.4 -1.3 -2.4 -0.8 0.2 1.1
Wears glasses or contact lenses 1.5 1.7 4.8 1.9 2.2 0.9 1.0 1.3 0.1 0.9 0.5
Ever taken oral contraceptive pill 1.0 1.1 2.7 1.6 1.0 1.1 -0.8 1.0 1.3 -0.7 0.4
Hearing aid user 1.0 1.1 3.7 1.3 -0.6 -0.2 0.1 1.6 -0.1 -1.9 0.1
Mother’s age at death 0.4 0.6 3.2 0.3 0.1 0.0 1.8 -0.6 0.5 0.6 0.5
Financial situation satisfaction 0.3 0.4 0.7 0.7 -0.5 0.3 -0.6 0.6 0.9 -0.5 -0.8
Tinnitus: Yes, now most or all of the time 0.6 0.7 3.8 0.2 1.9 0.6 -0.5 0.3 0.3 -0.9 0.3
Commuting to job workplace: Public transport 1.4 1.7 5.0 1.2 -0.9 0.1 -2.2 1.2 -0.6 -0.2 -2.0
Eye problems/disorders: Glaucoma 0.2 0.3 0.5 0.7 0.2 0.7 0.1 0.7 -0.1 0.1 -0.6
Medication: Blood pressure 0.6 1.1 2.0 0.9 -1.3 -1.1 0.5 1.2 0.5 -1.1 1.4
Pain type(s) experienced in last month: Hip pain 1.0 1.3 4.7 0.6 -2.2 -1.5 1.1 -0.1 -0.0 -0.7 1.0
Supplements: Fish oil (including cod liver oil) 0.6 0.7 4.0 -0.2 -2.0 -1.0 0.0 0.6 -0.7 -0.1 -0.1
High cholesterol (Self-reported) 0.4 0.8 1.5 1.0 -1.0 -1.1 -0.5 1.2 0.4 -0.4 1.0
Medication: Bendroflumethiazide 0.3 0.4 1.3 -0.3 -0.8 -0.9 1.1 -0.2 -0.6 -0.2 0.5
Medication: Paracetamol 0.3 0.5 2.1 -1.4 -0.5 -0.1 -0.3 -0.8 0.8 0.1 -0.6
Medication: Lisinopril 0.7 0.9 2.7 1.1 0.4 0.6 -1.3 1.6 0.3 -0.7 -0.8
Medication: Atorvastatin 0.3 0.3 1.5 -1.2 0.1 -0.1 -0.8 0.1 -0.6 -0.4 -0.2
Illnesses of father: High blood pressure 1.7 2.0 7.5 1.6 -1.2 -0.9 0.9 1.4 0.9 -0.6 2.7
Alcohol drinker status: Never 0.6 0.8 2.1 1.4 0.4 0.3 -0.9 0.1 -1.3 0.6 1.0
Ever smoked 0.9 1.5 3.8 -1.6 -1.4 -1.6 -0.1 -2.0 0.3 -1.0 -0.7
Basal metabolic rate 0.3 1.4 7.1 -0.6 0.8 0.8 -0.6 -1.3 -0.0 -0.7 -2.7
Leg fat percentage (left) 0.6 2.1 4.9 -2.2 -0.7 -0.5 -1.6 -2.2 0.1 0.3 1.9
Arm fat-free mass (left) 0.3 1.7 7.2 -0.8 1.4 1.3 -0.1 -1.3 0.2 -0.3 -2.7
Number of operations (self-reported) 0.9 1.4 4.0 1.1 -1.5 -2.0 0.4 -0.2 -0.2 -1.4 1.2
Average weekly beer plus cider intake 0.6 0.8 4.2 2.0 0.2 0.3 0.6 0.9 0.6 0.7 0.5
Irritability 0.8 1.4 4.0 0.9 -1.4 -1.6 -2.0 0.3 -0.4 -1.4 -0.4
Risk taking 1.6 2.4 7.9 -0.2 -2.8 -2.2 -1.3 0.1 -0.5 -2.0 0.5
Ever had prostate specific antigen (PSA) test 2.6 3.0 9.0 -2.0 2.9 3.0 -0.9 -0.5 0.3 1.1 -0.6
Fractured/broken bones in last 5 years 0.6 0.7 4.2 0.7 0.6 -0.1 2.1 0.9 0.2 0.2 0.0
Age started oral contraceptive pill 0.5 0.6 1.5 0.7 0.4 -1.2 0.3 1.2 -0.4 -0.8 0.8
Diastolic blood pressure, automated reading 0.5 1.7 4.7 -1.2 -2.1 -2.2 0.0 -1.2 -0.7 -0.4 0.8
Ever depressed for a whole week 1.1 1.4 5.5 2.3 -1.0 -1.1 0.9 1.0 0.4 -1.2 0.4
Unable to work because of sickness or disability 0.6 0.8 1.6 -1.0 -1.0 0.1 -0.9 -1.0 1.2 -0.6 0.8
Commuting to job workplace: Cycle 0.6 0.7 2.7 -0.7 -0.6 -0.6 0.2 -1.0 -0.3 0.9 -1.6
Myopia 2.5 3.7 12.3 3.5 1.4 0.4 1.3 3.0 2.0 -0.2 0.6
Vascular/heart problems diagnosed by doctor 0.1 0.3 1.2 0.3 0.5 0.5 -0.2 0.1 0.3 1.1 -0.8
Cholesterol lowering medication 0.4 0.5 1.3 0.0 -0.9 -0.4 -1.1 0.6 1.1 -0.2 0.4
Medication: Omeprazole (e.g. Zanprol) 0.3 0.3 1.2 -0.1 0.2 -0.0 0.3 -1.1 -0.6 -0.8 -0.7
Pain experienced in last month 1.0 1.7 4.8 -0.0 1.8 1.6 -1.1 -0.0 -2.2 1.4 -0.0
Supplements: Calcium 0.6 0.7 1.8 -0.0 1.1 0.9 -0.2 0.7 0.2 1.3 -1.0
Basal cell carcinoma (self-reported) 0.8 1.0 2.2 -0.9 0.6 0.7 1.3 -1.5 0.4 0.4 -1.3
Heart attack/myocardial infarction (self-reported) 0.4 0.5 1.9 1.4 0.6 0.7 0.2 0.1 -0.5 -0.5 0.9
Deep venous thrombosis (DVT) (self-reported) 0.5 0.6 2.3 -0.0 0.2 0.6 -0.9 0.6 1.0 1.5 -0.3
Heart disease (siblings) 1.1 1.3 4.2 -0.0 0.4 0.5 -1.4 0.5 1.1 1.5 -2.0
Alcohol drinker status: Previous 0.5 0.6 1.3 -0.6 1.1 -0.0 -0.1 -0.9 -0.8 -0.8 1.0
Pack years of smoking 0.2 0.4 0.8 -0.8 -0.3 0.2 -0.7 -0.9 0.7 -0.3 -0.5
Impedance of whole body 1.8 9.2 36.1 1.2 4.9 6.0 -2.9 0.6 0.4 1.6 -0.7
Leg fat mass (left) 0.3 1.1 2.9 -1.6 -0.4 -0.4 -1.6 -1.7 0.1 0.0 0.5
Arm predicted mass (left) 0.3 1.7 7.6 -0.9 1.5 1.2 -0.1 -1.2 0.0 -0.5 -2.8