[Hub]/) : Traits : Impedance of leg (right) : ← →

chr2:171,478,402-173,114,238

Best TWAS P=1.64e-27 · Best GWAS P=3.07e-29 conditioned to 0.000257

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
25	The Cancer Genome Atlas	Thyroid Carcinoma	CYBRD1	0.10	0.06	lasso	4	0.06	6.2e-07	9.4	-10.9	1.6e-27	-0.86	0.00	1.00	TRUE
7	GTEx	Breast Mammary Tissue	CYBRD1	0.32	0.21	enet	16	0.27	2.0e-14	9.4	-9.9	2.6e-23	-0.74	0.00	1.00	FALSE
11	GTEx	Esophagus Muscularis	CYBRD1	0.33	0.07	lasso	9	0.22	1.3e-13	7.9	-9.8	1.7e-22	-0.75	0.06	0.94	FALSE
8	GTEx	Breast Mammary Tissue (Male)	CYBRD1	0.35	0.24	lasso	6	0.20	2.4e-05	9.4	-9.7	2.1e-22	-0.72	0.00	0.98	FALSE
9	GTEx	Breast Mammary Tissue (Female)	CYBRD1	0.20	0.07	lasso	2	0.14	4.5e-05	9.4	-9.7	2.4e-22	-0.78	0.00	0.98	FALSE
2	GTEx	Adipose Subcutaneous	CYBRD1	0.35	0.19	lasso	6	0.24	7.3e-20	9.4	-9.7	5.2e-22	-0.77	0.00	1.00	FALSE
14	GTEx	Nerve Tibial	CYBRD1	0.36	0.07	lasso	10	0.20	2.3e-14	9.4	-9.6	8.6e-22	-0.73	0.00	1.00	FALSE
6	GTEx	Artery Tibial	CYBRD1	0.37	0.08	lasso	9	0.21	3.0e-16	7.9	-9.4	4.9e-21	-0.75	0.00	1.00	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	CYBRD1	0.37	0.16	lasso	9	0.30	3.0e-39	6.8	-9.3	8.8e-21	-0.77	0.30	0.70	FALSE
21	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	CYBRD1	0.14	0.04	enet	12	0.09	2.2e-05	11.2	9.3	1.3e-20	0.78	0.00	0.96	FALSE
13	GTEx	Muscle Skeletal	CYBRD1	0.10	0.00	enet	9	0.01	1.5e-02	9.4	-9.2	2.7e-20	-0.71	0.00	0.99	FALSE
3	GTEx	Adipose Visceral Omentum	CYBRD1	0.33	0.10	lasso	10	0.26	4.6e-14	6.4	-9.2	5.0e-20	-0.71	0.03	0.97	FALSE
15	GTEx	Thyroid	CYBRD1	0.26	0.08	enet	26	0.12	1.4e-09	9.4	-8.8	1.3e-18	-0.72	0.00	1.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CYBRD1	0.33	0.18	lasso	7	0.27	5.2e-33	-4.5	-8.3	1.3e-16	-0.69	1.00	0.00	FALSE
4	GTEx	Artery Aorta	CYBRD1	0.52	0.30	lasso	10	0.41	6.0e-24	-4.5	-8.2	3.7e-16	-0.66	0.96	0.04	FALSE
10	GTEx	Cells Transformed fibroblasts	CYBRD1	0.34	0.16	enet	27	0.26	6.3e-20	6.4	-7.8	6.2e-15	-0.57	1.00	0.00	FALSE
12	GTEx	Lung	CYBRD1	0.14	0.05	enet	8	0.10	5.6e-08	-4.5	-7.6	3.2e-14	-0.45	0.98	0.01	FALSE
5	GTEx	Artery Coronary	CYBRD1	0.29	0.01	enet	44	0.11	2.0e-04	6.4	-7.5	6.2e-14	-0.68	0.04	0.61	FALSE
22	The Cancer Genome Atlas	Colon Adenocarcinoma	CYBRD1	0.14	0.06	blup	69	0.05	6.4e-04	-5.7	6.7	1.8e-11	0.52	0.16	0.48	FALSE
17	GTEx	Whole Blood	CYBRD1	0.25	0.14	enet	19	0.15	1.4e-13	-4.7	-6.6	4.9e-11	-0.52	1.00	0.00	FALSE
18	METSIM	Adipose	CYBRD1	0.08	0.06	lasso	6	0.06	8.0e-09	-4.1	-6.3	3.5e-10	-0.48	0.92	0.08	FALSE
16	GTEx	Uterus	CYBRD1	0.54	0.04	lasso	6	0.19	1.1e-04	-5.3	-6.2	7.3e-10	-0.49	0.05	0.44	FALSE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	CYBRD1	0.08	0.06	blup	68	0.08	1.5e-08	6.8	-5.7	1.3e-08	-0.51	0.94	0.06	FALSE
23	The Cancer Genome Atlas	Brain Lower Grade Glioma	CYBRD1	0.03	0.02	lasso	3	0.03	4.5e-04	-4.5	-5.6	2.5e-08	-0.46	0.18	0.21	FALSE
19	NTR	Blood	METTL8	0.03	0.02	lasso	7	0.02	1.7e-08	-4.1	5.5	4.5e-08	0.37	1.00	0.00	FALSE