TWAS
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Traits
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Impedance of leg (right)
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chr2:176,342,243-177,746,117
Best TWAS P=2.8e-10 · Best GWAS P=9.11e-11 conditioned to 0.00252
176.4M
176.6M
176.8M
177M
177.2M
177.4M
177.6M
177.8M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
ROSMAP
Brain Pre-frontal Cortex
HOXD-AS1
0.11
0.06
lasso
6
0.09
1.4e-11
-4.7
6.3
2.8e-10
-0.67
0.18
0.82
TRUE