[Hub]/) : Traits : Impedance of leg (right) :

chr3:183,204,923-184,724,719

Best TWAS P=5e-22 · Best GWAS P=8.3e-24 conditioned to 0.000383

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ECE2 0.24 0.20 bslmm 542 0.19 1.6e-22 -9.2 -9.0 1.9e-19 -0.34 0.77 0.23 FALSE
2 GTEx Artery Tibial PSMD2 0.13 0.09 lasso 5 0.08 1.3e-06 5.1 -5.4 8.1e-08 -0.52 0.86 0.04 FALSE
3 GTEx Brain Putamen basal ganglia ECE2 0.38 0.03 enet 22 0.11 1.4e-03 -9.2 -7.0 1.7e-12 -0.28 0.07 0.24 FALSE
4 GTEx Esophagus Mucosa ABCF3 0.11 0.10 lasso 3 0.08 3.6e-06 6.9 -7.0 2.1e-12 -0.26 0.64 0.20 FALSE
5 GTEx Pancreas ECE2 0.26 0.04 enet 24 0.09 1.2e-04 -9.2 -5.9 4.6e-09 -0.21 0.15 0.13 FALSE
6 GTEx Pituitary ECE2 0.52 0.30 lasso 7 0.23 1.5e-06 -9.2 -7.6 2.8e-14 -0.28 0.31 0.39 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic ABCF3 0.15 0.10 lasso 4 0.11 1.1e-06 -6.5 -6.2 7.3e-10 -0.22 0.76 0.05 FALSE
8 GTEx Skin Sun Exposed Lower leg ABCF3 0.13 0.08 lasso 4 0.11 1.6e-09 -6.5 -8.4 6.1e-17 -0.33 0.96 0.03 FALSE
9 GTEx Skin Sun Exposed Lower leg PSMD2 0.13 0.14 lasso 4 0.15 1.4e-12 5.1 -5.1 3.1e-07 -0.50 1.00 0.00 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma ABCF3 0.04 0.00 enet 10 0.02 1.2e-04 -6.5 -5.2 1.5e-07 -0.16 0.01 0.98 FALSE
11 The Cancer Genome Atlas Colon Adenocarcinoma ABCF3 0.07 0.00 blup 51 0.01 4.4e-02 -6.6 -5.9 3.1e-09 -0.25 0.01 0.86 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma ECE2 0.04 0.02 blup 61 0.03 3.5e-04 -9.2 -7.9 3.0e-15 -0.22 0.48 0.13 FALSE
13 The Cancer Genome Atlas Liver Hepatocellular Carcinoma ABCF3 0.08 0.03 blup 51 0.06 6.1e-04 -2.8 -6.2 5.2e-10 -0.22 0.01 0.86 FALSE
14 The Cancer Genome Atlas Lung Adenocarcinoma PSMD2 0.09 0.02 blup 50 0.05 1.2e-06 10.1 -9.4 5.6e-21 -0.78 0.00 0.99 TRUE
15 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CAMK2N2 0.04 0.01 enet 8 0.03 3.9e-04 -3.9 -7.2 7.0e-13 -0.25 0.14 0.03 FALSE
16 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PSMD2 0.05 0.00 enet 10 0.01 3.6e-02 -9.2 -6.1 8.1e-10 -0.47 0.01 0.07 FALSE
17 The Cancer Genome Atlas Testicular Germ Cell Tumors VWA5B2 0.10 0.04 blup 51 0.04 1.8e-02 -6.6 9.7 5.0e-22 0.37 0.02 0.56 TRUE
18 The Cancer Genome Atlas Thyroid Carcinoma ABCF3 0.05 0.02 lasso 9 0.01 1.4e-02 -3.9 -5.6 1.7e-08 -0.21 0.03 0.93 FALSE