[Hub]/) : Traits : Impedance of leg (right) : ← →

chr3:183,204,923-184,724,719

Best TWAS P=5e-22 · Best GWAS P=8.3e-24 conditioned to 0.000383

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
17	The Cancer Genome Atlas	Testicular Germ Cell Tumors	VWA5B2	0.10	0.04	blup	51	0.04	1.8e-02	-6.6	9.7	5.0e-22	0.37	0.02	0.56	TRUE
14	The Cancer Genome Atlas	Lung Adenocarcinoma	PSMD2	0.09	0.02	blup	50	0.05	1.2e-06	10.1	-9.4	5.6e-21	-0.78	0.00	0.99	TRUE
1	CommonMind	Brain Pre-frontal Cortex	ECE2	0.24	0.20	bslmm	542	0.19	1.6e-22	-9.2	-9.0	1.9e-19	-0.34	0.77	0.23	FALSE
8	GTEx	Skin Sun Exposed Lower leg	ABCF3	0.13	0.08	lasso	4	0.11	1.6e-09	-6.5	-8.4	6.1e-17	-0.33	0.96	0.03	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	ECE2	0.04	0.02	blup	61	0.03	3.5e-04	-9.2	-7.9	3.0e-15	-0.22	0.48	0.13	FALSE
6	GTEx	Pituitary	ECE2	0.52	0.30	lasso	7	0.23	1.5e-06	-9.2	-7.6	2.8e-14	-0.28	0.31	0.39	FALSE
15	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CAMK2N2	0.04	0.01	enet	8	0.03	3.9e-04	-3.9	-7.2	7.0e-13	-0.25	0.14	0.03	FALSE
3	GTEx	Brain Putamen basal ganglia	ECE2	0.38	0.03	enet	22	0.11	1.4e-03	-9.2	-7.0	1.7e-12	-0.28	0.07	0.24	FALSE
4	GTEx	Esophagus Mucosa	ABCF3	0.11	0.10	lasso	3	0.08	3.6e-06	6.9	-7.0	2.1e-12	-0.26	0.64	0.20	FALSE
13	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ABCF3	0.08	0.03	blup	51	0.06	6.1e-04	-2.8	-6.2	5.2e-10	-0.22	0.01	0.86	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	ABCF3	0.15	0.10	lasso	4	0.11	1.1e-06	-6.5	-6.2	7.3e-10	-0.22	0.76	0.05	FALSE
16	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PSMD2	0.05	0.00	enet	10	0.01	3.6e-02	-9.2	-6.1	8.1e-10	-0.47	0.01	0.07	FALSE
11	The Cancer Genome Atlas	Colon Adenocarcinoma	ABCF3	0.07	0.00	blup	51	0.01	4.4e-02	-6.6	-5.9	3.1e-09	-0.25	0.01	0.86	FALSE
5	GTEx	Pancreas	ECE2	0.26	0.04	enet	24	0.09	1.2e-04	-9.2	-5.9	4.6e-09	-0.21	0.15	0.13	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	ABCF3	0.05	0.02	lasso	9	0.01	1.4e-02	-3.9	-5.6	1.7e-08	-0.21	0.03	0.93	FALSE
2	GTEx	Artery Tibial	PSMD2	0.13	0.09	lasso	5	0.08	1.3e-06	5.1	-5.4	8.1e-08	-0.52	0.86	0.04	FALSE
10	The Cancer Genome Atlas	Breast Invasive Carcinoma	ABCF3	0.04	0.00	enet	10	0.02	1.2e-04	-6.5	-5.2	1.5e-07	-0.16	0.01	0.98	FALSE
9	GTEx	Skin Sun Exposed Lower leg	PSMD2	0.13	0.14	lasso	4	0.15	1.4e-12	5.1	-5.1	3.1e-07	-0.50	1.00	0.00	FALSE