TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Impedance of leg (right)
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chr5:36,410,564-38,450,430
Best TWAS P=5.32e-11 · Best GWAS P=7.76e-12 conditioned to 0.000641
36.5M
37M
37.5M
38M
38.5M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
WDR70
0.06
0.03
lasso
8
0.03
0.00346
5.9
-6.6
5.3e-11
-0.65
0.18
0.73
TRUE
5
The Cancer Genome Atlas
Ovarian Serous Cystadenocarcinoma
C5orf42
0.04
0.05
lasso
3
0.04
0.00108
6.5
-6.4
1.7e-10
-0.57
0.03
0.42
FALSE
2
GTEx
Nerve Tibial
WDR70
0.17
0.07
lasso
3
0.05
0.00014
-6.0
-5.9
3.0e-09
-0.25
0.23
0.43
FALSE
4
GTEx
Whole Blood
C5orf42
0.07
0.00
enet
16
0.01
0.01830
6.4
-5.9
3.3e-09
-0.45
0.07
0.30
FALSE
3
GTEx
Whole Blood
NUP155
0.05
0.01
enet
14
0.04
0.00011
6.4
-5.4
7.2e-08
-0.38
0.08
0.29
FALSE