[Hub]/) : Traits : Impedance of leg (right) : ← →

chr5:42,076,094-44,403,631

Best TWAS P=5.78e-10 · Best GWAS P=1.15e-08 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Brain Caudate basal ganglia	C5orf34	0.14	-0.01	enet	14	0.00	3.3e-01	-4.8	-6.2	5.8e-10	0.59	0.08	0.42	TRUE
4	GTEx	Esophagus Gastroesophageal Junction	NNT-AS1	0.12	-0.01	enet	34	0.03	2.1e-02	4.0	-5.2	1.7e-07	0.28	0.04	0.09	TRUE
1	GTEx	Adipose Subcutaneous	CCDC152	0.09	0.04	lasso	4	0.02	6.4e-03	-5.1	-5.2	1.9e-07	0.11	0.02	0.97	TRUE
7	GTEx	Thyroid	C5orf34	0.08	0.08	lasso	3	0.06	1.4e-05	-5.1	-5.8	6.6e-09	0.63	0.05	0.93	FALSE
12	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C5orf34	0.05	0.06	blup	39	0.05	3.2e-06	-4.8	-5.8	6.6e-09	0.58	0.01	0.98	FALSE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	HMGCS1	0.04	0.03	blup	37	0.03	1.5e-04	-4.8	5.6	1.9e-08	-0.88	0.02	0.96	FALSE
6	GTEx	Skin Sun Exposed Lower leg	NNT	0.05	0.04	enet	11	0.04	4.3e-04	-4.8	-5.6	2.7e-08	0.65	0.14	0.77	FALSE
10	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C5orf34	0.04	0.01	enet	4	0.03	1.5e-03	-4.8	-5.5	3.0e-08	0.49	0.01	0.71	FALSE
14	The Cancer Genome Atlas	Stomach Adenocarcinoma	C5orf34	0.09	0.02	enet	9	0.04	3.7e-04	-4.7	-5.5	3.6e-08	0.58	0.01	0.80	FALSE
11	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C5orf34	0.11	0.12	enet	13	0.11	2.9e-12	-4.8	-5.5	4.9e-08	0.54	0.01	0.98	FALSE
2	GTEx	Adrenal Gland	NNT	0.17	0.15	lasso	4	0.07	1.3e-03	4.8	-5.4	7.6e-08	0.56	0.13	0.79	FALSE
5	GTEx	Esophagus Mucosa	NNT	0.31	0.24	lasso	8	0.26	1.4e-17	-3.8	-5.3	1.3e-07	0.54	0.89	0.07	FALSE
8	GTEx	Thyroid	CCDC152	0.10	0.07	lasso	4	0.04	4.2e-04	-5.1	-5.1	3.0e-07	0.11	0.02	0.97	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	SEPP1	0.18	0.19	lasso	11	0.21	1.3e-26	-4.8	5.1	3.0e-07	-0.12	0.06	0.94	FALSE