[Hub]/) : Traits : Impedance of leg (right) : ← →

chr5:42,076,094-44,403,631

Best TWAS P=5.78e-10 · Best GWAS P=1.15e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CCDC152 0.09 0.04 lasso 4 0.02 6.4e-03 -5.1 -5.2 1.9e-07 0.11 0.02 0.97 TRUE
2 GTEx Adrenal Gland NNT 0.17 0.15 lasso 4 0.07 1.3e-03 4.8 -5.4 7.6e-08 0.56 0.13 0.79 FALSE
3 GTEx Brain Caudate basal ganglia C5orf34 0.14 -0.01 enet 14 0.00 3.3e-01 -4.8 -6.2 5.8e-10 0.59 0.08 0.42 TRUE
4 GTEx Esophagus Gastroesophageal Junction NNT-AS1 0.12 -0.01 enet 34 0.03 2.1e-02 4.0 -5.2 1.7e-07 0.28 0.04 0.09 TRUE
5 GTEx Esophagus Mucosa NNT 0.31 0.24 lasso 8 0.26 1.4e-17 -3.8 -5.3 1.3e-07 0.54 0.89 0.07 FALSE
6 GTEx Skin Sun Exposed Lower leg NNT 0.05 0.04 enet 11 0.04 4.3e-04 -4.8 -5.6 2.7e-08 0.65 0.14 0.77 FALSE
7 GTEx Thyroid C5orf34 0.08 0.08 lasso 3 0.06 1.4e-05 -5.1 -5.8 6.6e-09 0.63 0.05 0.93 FALSE
8 GTEx Thyroid CCDC152 0.10 0.07 lasso 4 0.04 4.2e-04 -5.1 -5.1 3.0e-07 0.11 0.02 0.97 FALSE
9 ROSMAP Brain Pre-frontal Cortex SEPP1 0.18 0.19 lasso 11 0.21 1.3e-26 -4.8 5.1 3.0e-07 -0.12 0.06 0.94 FALSE
10 The Cancer Genome Atlas Bladder Urothelial Carcinoma C5orf34 0.04 0.01 enet 4 0.03 1.5e-03 -4.8 -5.5 3.0e-08 0.49 0.01 0.71 FALSE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C5orf34 0.11 0.12 enet 13 0.11 2.9e-12 -4.8 -5.5 4.9e-08 0.54 0.01 0.98 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C5orf34 0.05 0.06 blup 39 0.05 3.2e-06 -4.8 -5.8 6.6e-09 0.58 0.01 0.98 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma HMGCS1 0.04 0.03 blup 37 0.03 1.5e-04 -4.8 5.6 1.9e-08 -0.88 0.02 0.96 FALSE
14 The Cancer Genome Atlas Stomach Adenocarcinoma C5orf34 0.09 0.02 enet 9 0.04 3.7e-04 -4.7 -5.5 3.6e-08 0.58 0.01 0.80 FALSE