[Hub]/) : Traits : Impedance of leg (right) : ← →

chr5:129,797,129-131,668,698

Best TWAS P=2.37e-12 · Best GWAS P=9.96e-13 conditioned to 0.00488

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Artery Aorta	HINT1	0.07	0.07	enet	8	0.06	4.7e-04	6.4	7.0	2.4e-12	0.75	0.06	0.69	TRUE
1	GTEx	Adipose Subcutaneous	HINT1	0.10	0.07	enet	16	0.06	8.8e-06	5.6	6.8	7.7e-12	0.49	0.70	0.14	FALSE
4	GTEx	Cells Transformed fibroblasts	HINT1	0.10	0.06	lasso	2	0.05	2.1e-04	6.0	6.2	4.5e-10	0.57	0.51	0.35	FALSE
5	GTEx	Testis	RAPGEF6	0.50	0.35	lasso	4	0.32	6.5e-15	5.6	6.2	6.2e-10	0.89	0.05	0.95	FALSE
3	GTEx	Artery Tibial	HINT1	0.11	0.04	enet	18	0.06	1.0e-05	6.0	6.1	1.1e-09	0.55	0.15	0.74	FALSE
8	The Cancer Genome Atlas	Thyroid Carcinoma	HINT1	0.07	0.04	lasso	2	0.01	1.8e-02	5.8	5.8	5.9e-09	0.57	0.00	0.98	FALSE
7	The Cancer Genome Atlas	Lung Adenocarcinoma	LYRM7	0.03	0.01	enet	10	0.02	7.5e-04	4.7	-5.7	1.6e-08	-0.74	0.01	0.83	FALSE
6	The Cancer Genome Atlas	Brain Lower Grade Glioma	HINT1	0.06	0.03	enet	5	0.03	5.2e-04	4.5	5.4	8.1e-08	0.74	0.06	0.57	FALSE