[Hub]/) : Traits : Impedance of leg (right) :

chr6:44,079,216-46,043,561

Best TWAS P=6.46e-15 · Best GWAS P=1.82e-15 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Caudate basal ganglia SUPT3H 0.22 0.12 lasso 6 0.10 8.1e-04 7.2 6.9 3.8e-12 0.87 0.05 0.84 FALSE
2 GTEx Brain Cerebellar Hemisphere SUPT3H 0.38 0.40 lasso 2 0.34 1.3e-09 7.2 7.2 4.3e-13 0.84 0.09 0.90 FALSE
3 GTEx Brain Cortex SUPT3H 0.28 0.01 lasso 7 0.01 2.1e-01 7.9 7.8 6.5e-15 0.98 0.03 0.90 TRUE
4 GTEx Brain Frontal Cortex BA9 SUPT3H 0.37 0.14 lasso 11 0.18 1.3e-05 7.2 5.2 2.5e-07 0.77 0.08 0.87 FALSE
5 GTEx Brain Hypothalamus SUPT3H 0.33 0.03 lasso 8 0.03 5.9e-02 7.1 6.9 6.6e-12 0.79 0.05 0.66 FALSE
6 GTEx Brain Nucleus accumbens basal ganglia SUPT3H 0.16 0.11 lasso 4 0.08 3.6e-03 7.1 7.3 2.1e-13 0.94 0.04 0.82 FALSE
7 GTEx Cells Transformed fibroblasts SUPT3H 0.15 0.10 lasso 4 0.13 8.8e-10 -3.4 6.2 6.0e-10 0.70 0.86 0.14 FALSE
8 GTEx Pituitary SUPT3H 0.26 0.08 lasso 6 0.05 1.8e-02 6.6 6.0 1.8e-09 0.80 0.06 0.45 FALSE
9 GTEx Testis SUPT3H 0.30 0.16 lasso 7 0.17 6.7e-08 7.1 6.6 3.6e-11 0.93 0.02 0.98 FALSE
10 NTR Blood SUPT3H 0.03 0.02 lasso 7 0.02 1.9e-07 6.8 6.4 1.9e-10 0.70 0.95 0.05 FALSE
11 ROSMAP Brain Pre-frontal Cortex SUPT3H 0.15 0.13 blup 643 0.17 3.4e-21 7.2 5.8 5.2e-09 0.82 0.08 0.92 FALSE
12 YFS Blood SUPT3H 0.06 0.09 lasso 13 0.12 2.2e-36 -4.2 6.3 2.3e-10 0.77 0.99 0.01 FALSE
13 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SUPT3H 0.04 0.01 blup 191 0.02 6.5e-03 7.8 6.3 2.4e-10 0.85 0.08 0.88 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma SUPT3H 0.07 0.05 enet 12 0.08 1.1e-09 7.1 6.3 2.3e-10 0.83 0.25 0.75 FALSE
15 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SUPT3H 0.06 0.05 lasso 3 0.05 3.9e-06 7.8 7.8 8.1e-15 0.99 0.02 0.98 FALSE
16 The Cancer Genome Atlas Stomach Adenocarcinoma SUPT3H 0.05 0.01 blup 191 0.00 1.4e-01 7.2 6.9 5.1e-12 0.93 0.04 0.71 FALSE