[Hub]/) : Traits : Impedance of leg (right) : ← →

chr6:87,167,376-89,108,830

Best TWAS P=4.4e-13 · Best GWAS P=7.9e-14 conditioned to 0.00993

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ZNF292	0.04	0.05	lasso	12	0.03	4.1e-05	5.8	-5.9	4.7e-09	0.59	0.59	0.40	FALSE
2	GTEx	Artery Aorta	RP11-393I2.4	0.10	0.03	lasso	5	0.02	2.4e-02	4.4	-5.2	1.9e-07	0.63	0.12	0.78	FALSE
3	GTEx	Brain Cortex	SMIM8	0.43	0.24	enet	44	0.34	4.6e-10	4.8	5.2	2.4e-07	-0.61	0.62	0.36	FALSE
4	GTEx	Cells EBV-transformed lymphocytes	C6orf163	0.18	0.14	lasso	4	0.15	1.5e-05	5.5	5.3	9.6e-08	-0.59	0.62	0.11	FALSE
5	GTEx	Cells Transformed fibroblasts	SMIM8	0.18	0.14	lasso	5	0.12	1.4e-09	5.5	-5.5	3.8e-08	0.59	1.00	0.00	FALSE
6	GTEx	Cells Transformed fibroblasts	C6orf163	0.16	0.14	lasso	3	0.18	2.7e-13	5.4	5.3	1.1e-07	-0.56	1.00	0.00	FALSE
7	GTEx	Nerve Tibial	ZNF292	0.09	0.07	enet	16	0.10	1.5e-07	-6.6	-6.2	5.3e-10	0.72	0.90	0.10	FALSE
8	GTEx	Nerve Tibial	RP11-393I2.4	0.08	0.09	enet	18	0.09	6.8e-07	5.1	-5.9	3.8e-09	0.65	0.92	0.07	FALSE
9	GTEx	Stomach	C6orf163	0.10	0.06	lasso	1	0.05	2.3e-03	5.4	5.4	5.8e-08	-0.59	0.34	0.08	FALSE
10	METSIM	Adipose	AKIRIN2	0.04	0.03	lasso	3	0.02	6.3e-04	4.7	-5.2	2.2e-07	0.48	0.26	0.55	FALSE
11	METSIM	Adipose	C6orf164	0.05	0.06	lasso	8	0.06	9.3e-10	5.4	5.3	1.3e-07	-0.61	0.99	0.01	FALSE
12	NTR	Blood	C6orf162	0.02	0.02	blup	411	0.02	1.7e-08	-6.8	5.2	2.0e-07	-0.60	0.77	0.23	FALSE
13	ROSMAP	Brain Pre-frontal Cortex	SMIM8	0.21	0.33	enet	34	0.38	3.9e-52	-6.5	6.2	7.4e-10	-0.62	0.71	0.29	FALSE
14	ROSMAP	Brain Pre-frontal Cortex	SLC35A1	0.30	0.48	enet	25	0.50	5.7e-73	-7.3	-7.0	2.2e-12	0.95	0.03	0.97	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	C6orf163	0.07	0.03	enet	16	0.06	9.1e-09	2.5	-5.5	3.1e-08	0.52	0.90	0.10	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	C6orf164	0.06	0.05	blup	94	0.06	1.0e-11	-6.2	6.5	1.0e-10	-0.58	0.04	0.96	FALSE
17	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	C6orf164	0.07	0.06	blup	95	0.05	2.0e-03	-6.8	6.8	1.4e-11	-0.72	0.02	0.95	FALSE
18	The Cancer Genome Atlas	Colon Adenocarcinoma	C6orf164	0.05	0.02	enet	8	0.02	1.9e-02	-6.6	6.6	5.3e-11	-0.67	0.02	0.71	FALSE
19	The Cancer Genome Atlas	Esophageal Carcinoma	C6orf164	0.15	0.07	enet	10	0.04	1.7e-02	4.9	5.1	2.7e-07	-0.64	0.02	0.80	FALSE
20	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C6orf164	0.06	0.08	blup	94	0.08	8.3e-09	-6.6	7.0	3.1e-12	-0.69	0.01	0.99	FALSE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SLC35A1	0.02	0.01	blup	72	0.00	8.7e-02	-7.3	7.2	4.4e-13	-0.84	0.01	0.91	TRUE
22	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C6orf164	0.11	0.12	blup	95	0.14	5.0e-15	-6.6	6.2	4.6e-10	-0.64	0.01	0.99	FALSE
23	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C6orf164	0.11	0.14	enet	8	0.12	1.6e-07	-6.5	6.7	2.2e-11	-0.68	0.02	0.98	FALSE
24	The Cancer Genome Atlas	Brain Lower Grade Glioma	C6orf164	0.04	0.02	blup	95	0.04	5.4e-05	5.5	6.7	1.7e-11	-0.71	0.04	0.96	FALSE
25	The Cancer Genome Atlas	Lung Adenocarcinoma	C6orf164	0.09	0.12	blup	95	0.11	4.1e-13	-6.5	6.5	8.3e-11	-0.71	0.02	0.98	FALSE
26	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C6orf164	0.06	0.06	lasso	4	0.07	4.6e-08	-6.8	6.7	2.1e-11	-0.67	0.01	0.99	FALSE
27	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C6orf163	0.06	0.02	blup	66	0.02	1.1e-02	5.5	6.2	7.1e-10	-0.65	0.07	0.62	FALSE
28	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C6orf164	0.12	0.12	blup	95	0.14	7.4e-10	-6.1	6.8	1.4e-11	-0.73	0.02	0.98	FALSE
29	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SLC35A1	0.04	0.03	lasso	5	0.02	1.3e-02	-7.3	7.2	7.6e-13	-0.94	0.01	0.91	FALSE
30	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C6orf164	0.07	0.11	enet	8	0.10	8.4e-05	-6.7	6.5	6.5e-11	-0.68	0.02	0.96	FALSE
31	The Cancer Genome Atlas	Prostate Adenocarcinoma	C6orf164	0.13	0.10	blup	95	0.11	1.5e-11	-6.6	6.2	5.5e-10	-0.58	0.01	0.99	FALSE
32	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC35A1	0.05	0.03	blup	72	0.05	6.8e-06	4.5	5.3	1.0e-07	-0.53	0.82	0.16	FALSE
33	The Cancer Genome Atlas	Stomach Adenocarcinoma	C6orf164	0.17	0.13	lasso	4	0.10	6.2e-08	-6.7	6.7	2.1e-11	-0.67	0.01	0.99	FALSE
34	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C6orf164	0.12	0.08	enet	9	0.09	5.6e-04	4.3	5.9	3.2e-09	-0.60	0.04	0.90	FALSE
35	The Cancer Genome Atlas	Testicular Germ Cell Tumors	SLC35A1	0.14	0.04	blup	72	0.07	1.4e-03	-2.9	6.5	6.6e-11	-0.78	0.01	0.82	FALSE
36	The Cancer Genome Atlas	Thyroid Carcinoma	AKIRIN2	0.06	0.00	blup	49	0.01	2.4e-02	6.9	-5.3	1.3e-07	0.64	0.01	0.54	FALSE
37	The Cancer Genome Atlas	Thyroid Carcinoma	C6orf164	0.18	0.24	lasso	4	0.25	1.4e-24	-6.5	6.6	3.0e-11	-0.68	0.02	0.98	FALSE
38	The Cancer Genome Atlas	Thyroid Carcinoma	SLC35A1	0.08	0.07	enet	17	0.07	5.0e-07	-7.3	-7.0	2.5e-12	0.91	0.01	0.99	FALSE