[Hub]/) : Traits : Impedance of leg (right) : ← →

chr6:41,005,502-42,598,371

Best TWAS P=8.13e-18 · Best GWAS P=2.26e-15 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	MED20	0.08	0.07	enet	9	0.05	4.7e-05	-5.7	-5.7	9.6e-09	-0.61	0.74	0.24	FALSE
2	GTEx	Artery Tibial	MED20	0.14	0.11	lasso	2	0.09	9.7e-08	-5.7	-5.7	1.5e-08	-0.59	0.98	0.02	FALSE
3	GTEx	Cells Transformed fibroblasts	MED20	0.11	0.05	lasso	4	0.08	9.4e-07	7.8	-8.1	6.9e-16	-0.81	0.01	0.99	FALSE
4	GTEx	Cells Transformed fibroblasts	USP49	0.13	0.02	lasso	4	0.02	2.4e-02	7.9	7.1	1.7e-12	0.93	0.01	0.97	FALSE
5	GTEx	Colon Transverse	MED20	0.17	0.01	enet	10	0.06	6.0e-04	-5.7	-6.5	7.1e-11	-0.51	0.39	0.12	FALSE
6	GTEx	Esophagus Mucosa	MED20	0.09	0.07	enet	10	0.02	2.7e-02	5.6	-5.8	7.2e-09	-0.62	0.84	0.04	FALSE
7	GTEx	Esophagus Muscularis	MED20	0.15	0.05	lasso	7	0.04	1.0e-03	5.7	-5.6	1.8e-08	-0.59	0.66	0.26	FALSE
8	GTEx	Heart Atrial Appendage	MED20	0.14	0.12	enet	11	0.09	5.9e-05	-5.4	-5.3	1.4e-07	-0.55	0.74	0.20	FALSE
9	GTEx	Heart Left Ventricle	MED20	0.22	0.19	enet	8	0.12	5.8e-07	-5.7	-5.9	2.9e-09	-0.61	1.00	0.00	FALSE
10	GTEx	Lung	BYSL	0.08	0.03	lasso	4	0.02	4.9e-03	-6.5	6.6	3.1e-11	0.55	0.58	0.04	FALSE
11	GTEx	Lung	MED20	0.10	0.01	lasso	4	0.00	2.7e-01	1.4	-5.4	7.6e-08	-0.40	0.08	0.08	FALSE
12	GTEx	Lung	USP49	0.09	0.08	lasso	2	0.05	6.2e-05	7.9	7.6	2.4e-14	0.99	0.01	0.99	FALSE
13	GTEx	Nerve Tibial	MED20	0.13	0.11	enet	8	0.10	1.5e-07	-5.4	-5.6	2.5e-08	-0.60	0.99	0.01	FALSE
14	GTEx	Testis	MED20	0.13	0.03	lasso	6	0.00	2.0e-01	7.9	-7.8	5.6e-15	-0.99	0.02	0.90	FALSE
15	GTEx	Thyroid	MED20	0.05	0.05	lasso	2	0.02	8.1e-03	-5.7	-6.0	1.7e-09	-0.62	0.67	0.14	FALSE
16	GTEx	Thyroid	FRS3	0.20	0.16	lasso	4	0.16	5.2e-12	-6.7	-6.6	5.2e-11	-0.35	0.97	0.03	FALSE
17	METSIM	Adipose	MED20	0.13	0.11	enet	27	0.11	2.3e-16	-5.6	-6.2	6.5e-10	-0.75	0.99	0.01	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	PGC	0.13	0.06	blup	520	0.06	3.2e-08	-6.7	6.5	6.0e-11	0.57	0.96	0.04	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	MED20	0.10	0.10	enet	21	0.09	6.0e-12	-5.7	-5.4	7.8e-08	-0.59	1.00	0.00	FALSE
20	The Cancer Genome Atlas	Breast Invasive Carcinoma	CCND3	0.04	0.00	blup	99	0.01	1.8e-03	7.9	-6.3	2.7e-10	-0.69	0.01	0.55	FALSE
21	The Cancer Genome Atlas	Colon Adenocarcinoma	MED20	0.05	0.00	blup	50	0.04	2.8e-03	-4.4	-8.2	3.1e-16	-0.85	0.02	0.76	FALSE
22	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MED20	0.04	0.03	lasso	3	0.04	7.3e-05	7.8	-7.9	3.3e-15	-0.97	0.00	0.99	FALSE
23	The Cancer Genome Atlas	Brain Lower Grade Glioma	MED20	0.09	0.08	enet	12	0.09	5.5e-10	-5.7	-6.6	5.4e-11	-0.58	1.00	0.00	FALSE
24	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	MED20	0.09	0.07	lasso	5	0.07	3.4e-04	7.9	-8.6	8.1e-18	-0.99	0.00	0.99	TRUE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	MED20	0.04	0.06	enet	6	0.05	2.6e-06	-4.4	-5.5	3.0e-08	-0.67	0.60	0.35	FALSE
26	The Cancer Genome Atlas	Stomach Adenocarcinoma	MED20	0.03	0.05	lasso	2	0.04	1.2e-03	7.8	-8.0	1.5e-15	-0.96	0.01	0.89	FALSE
27	The Cancer Genome Atlas	Thyroid Carcinoma	BYSL	0.05	0.06	enet	7	0.06	4.3e-06	-5.7	5.6	1.9e-08	0.56	0.85	0.06	FALSE