Best TWAS P=3.52e-08 · Best GWAS P=5.98e-06 conditioned to 0.268
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | MANEA | 0.28 | 0.15 | enet | 28 | 0.29 | 9.4e-22 | 3.9 | -5.2 | 2.4e-07 | -0.78 | 0.02 | 0.83 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | MANEA | 0.04 | 0.02 | blup | 58 | 0.03 | 4.9e-06 | 3.9 | -5.3 | 1.0e-07 | -0.62 | 0.02 | 0.55 | FALSE |
| 3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | MANEA | 0.19 | 0.03 | blup | 58 | 0.12 | 1.3e-05 | -3.9 | -5.5 | 3.5e-08 | -0.67 | 0.02 | 0.41 | TRUE |