TWAS
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About
Usage
Models
Genes
Traits
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Traits
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Impedance of leg (right)
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chr6:95,334,164-96,753,452
Best TWAS P=3.52e-08 · Best GWAS P=5.98e-06 conditioned to 0.268
95.4M
95.6M
95.8M
96M
96.2M
96.4M
96.6M
96.8M
0
1
2
3
4
5
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Pancreatic Adenocarcinoma
MANEA
0.19
0.03
blup
58
0.12
1.3e-05
-3.9
-5.5
3.5e-08
-0.67
0.02
0.41
TRUE
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
MANEA
0.04
0.02
blup
58
0.03
4.9e-06
3.9
-5.3
1.0e-07
-0.62
0.02
0.55
FALSE
1
GTEx
Cells Transformed fibroblasts
MANEA
0.28
0.15
enet
28
0.29
9.4e-22
3.9
-5.2
2.4e-07
-0.78
0.02
0.83
FALSE