Best TWAS P=1.92e-21 · Best GWAS P=3.37e-23 conditioned to 1.23e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | JAZF1 | 0.04 | 0.02 | blup | 224 | 0.03 | 3.8e-06 | 5.0 | 6.2 | 6.0e-10 | 0.49 | 0.55 | 0.29 | TRUE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | JAZF1 | 0.12 | 0.09 | lasso | 4 | 0.09 | 2.1e-09 | 8.8 | 9.5 | 1.9e-21 | 0.84 | 0.02 | 0.98 | TRUE |