TWAS
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Usage
Models
Genes
Traits
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Traits
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Impedance of leg (left)
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chr7:138,121,329-140,010,108
Best TWAS P=7.04e-10 · Best GWAS P=1.55e-10 conditioned to 1
138.5M
139M
139.5M
140M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
TTC26
0.06
0.03
lasso
4
0.03
0.0001
6.4
6.2
7e-10
0.97
0.00
1.00
TRUE
2
The Cancer Genome Atlas
Lung Adenocarcinoma
PARP12
0.02
0.01
blup
68
0.01
0.0237
-4.6
5.5
4e-08
-0.05
0.01
0.79
TRUE