Best TWAS P=1.06e-29 · Best GWAS P=5.53e-29 conditioned to 8.56e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | MMP16 | 0.12 | 0.07 | lasso | 4 | 0.08 | 4.3e-09 | 11.2 | 7.0 | 2.4e-12 | 0.88 | 0.00 | 1.00 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | MMP16 | 0.10 | 0.08 | blup | 131 | 0.05 | 1.3e-03 | 11.1 | 8.7 | 2.6e-18 | 0.84 | 0.00 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | MMP16 | 0.04 | 0.02 | lasso | 3 | 0.03 | 6.3e-05 | 7.9 | 6.4 | 1.8e-10 | 0.72 | 0.02 | 0.92 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | MMP16 | 0.10 | 0.09 | lasso | 4 | 0.08 | 2.9e-08 | 11.2 | 11.3 | 1.1e-29 | 0.93 | 0.00 | 1.00 | TRUE |