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Impedance of leg (left)
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chr8:88,801,153-89,582,625
Best TWAS P=1.06e-29 · Best GWAS P=5.53e-29 conditioned to 8.56e-06
88.8M
88.9M
89M
89.1M
89.2M
89.3M
89.4M
89.5M
89.6M
0
5
10
15
20
25
30
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Thyroid Carcinoma
MMP16
0.10
0.09
lasso
4
0.08
2.9e-08
11.2
11.3
1.1e-29
0.93
0.00
1.00
TRUE
1
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
MMP16
0.12
0.07
lasso
4
0.08
4.3e-09
11.2
7.0
2.4e-12
0.88
0.00
1.00
TRUE
2
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
MMP16
0.10
0.08
blup
131
0.05
1.3e-03
11.1
8.7
2.6e-18
0.84
0.00
0.99
FALSE
3
The Cancer Genome Atlas
Lung Adenocarcinoma
MMP16
0.04
0.02
lasso
3
0.03
6.3e-05
7.9
6.4
1.8e-10
0.72
0.02
0.92
FALSE