Best TWAS P=2.63e-10 · Best GWAS P=5.69e-14 conditioned to 0.605
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | STAU2 | 0.10 | 0.02 | lasso | 3 | 0.01 | 0.0574 | -5.4 | -6.3 | 2.6e-10 | 0.83 | 0.08 | 0.87 | TRUE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | UBE2W | 0.01 | 0.01 | blup | 43 | 0.01 | 0.0083 | -5.3 | -5.2 | 2.3e-07 | 0.40 | 0.04 | 0.05 | TRUE |