[Hub]/) : Traits : Impedance of leg (left) : ← →

chr1:112,312,154-114,196,883

Best TWAS P=5.8e-13 · Best GWAS P=2.22e-10 conditioned to 0.326

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Skin Not Sun Exposed Suprapubic	SLC16A1	0.12	0.00	lasso	5	0.04	5.0e-03	-5.9	7.2	5.8e-13	-0.80	0.02	0.88	TRUE
1	CommonMind	Brain Pre-frontal Cortex	WNT2B	0.43	0.46	enet	44	0.47	7.4e-64	-6.1	-6.0	2.3e-09	0.93	0.01	0.99	FALSE
3	GTEx	Brain Frontal Cortex BA9	WNT2B	0.29	0.28	lasso	3	0.29	2.6e-08	-6.3	-6.0	2.6e-09	0.93	0.01	0.99	FALSE
8	The Cancer Genome Atlas	Thyroid Carcinoma	MOV10	0.06	0.06	lasso	7	0.05	9.4e-06	-5.2	-5.9	4.1e-09	0.94	0.01	0.99	FALSE
2	GTEx	Brain Cortex	WNT2B	0.36	0.19	lasso	5	0.23	5.5e-07	-5.9	-5.7	9.5e-09	0.89	0.02	0.97	FALSE
7	ROSMAP	Brain Pre-frontal Cortex	WNT2B	0.34	0.40	enet	30	0.42	1.5e-59	-5.9	-5.7	1.3e-08	0.93	0.03	0.97	FALSE
6	GTEx	Skin Sun Exposed Lower leg	MOV10	0.05	0.02	lasso	5	0.02	1.1e-02	-5.9	-5.6	1.7e-08	0.80	0.03	0.92	FALSE
4	GTEx	Pituitary	ST7L	0.31	0.18	lasso	7	0.18	3.0e-05	-5.3	-5.3	9.1e-08	0.81	0.02	0.97	FALSE