[Hub]/) : Traits : Impedance of leg (left) : ← →

chr1:112,312,154-114,196,883

Best TWAS P=5.8e-13 · Best GWAS P=2.22e-10 conditioned to 0.326

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex WNT2B 0.43 0.46 enet 44 0.47 7.4e-64 -6.1 -6.0 2.3e-09 0.93 0.01 0.99 FALSE
2 GTEx Brain Cortex WNT2B 0.36 0.19 lasso 5 0.23 5.5e-07 -5.9 -5.7 9.5e-09 0.89 0.02 0.97 FALSE
3 GTEx Brain Frontal Cortex BA9 WNT2B 0.29 0.28 lasso 3 0.29 2.6e-08 -6.3 -6.0 2.6e-09 0.93 0.01 0.99 FALSE
4 GTEx Pituitary ST7L 0.31 0.18 lasso 7 0.18 3.0e-05 -5.3 -5.3 9.1e-08 0.81 0.02 0.97 FALSE
5 GTEx Skin Not Sun Exposed Suprapubic SLC16A1 0.12 0.00 lasso 5 0.04 5.0e-03 -5.9 7.2 5.8e-13 -0.80 0.02 0.88 TRUE
6 GTEx Skin Sun Exposed Lower leg MOV10 0.05 0.02 lasso 5 0.02 1.1e-02 -5.9 -5.6 1.7e-08 0.80 0.03 0.92 FALSE
7 ROSMAP Brain Pre-frontal Cortex WNT2B 0.34 0.40 enet 30 0.42 1.5e-59 -5.9 -5.7 1.3e-08 0.93 0.03 0.97 FALSE
8 The Cancer Genome Atlas Thyroid Carcinoma MOV10 0.06 0.06 lasso 7 0.05 9.4e-06 -5.2 -5.9 4.1e-09 0.94 0.01 0.99 FALSE