Best TWAS P=8.75e-11 · Best GWAS P=1.27e-11 conditioned to 0.0248
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Female) | HAUS6 | 0.13 | 0.01 | lasso | 1 | 0.00 | 4.2e-01 | -0.41 | -5.7 | 1.2e-08 | -0.62 | 0.06 | 0.25 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | PLIN2 | 0.08 | 0.02 | lasso | 4 | 0.03 | 1.5e-03 | 6.26 | 6.5 | 8.7e-11 | 0.88 | 0.04 | 0.90 | TRUE |
| 3 | GTEx | Esophagus Muscularis | HAUS6 | 0.22 | 0.09 | lasso | 4 | 0.11 | 4.6e-07 | 4.23 | -5.3 | 1.2e-07 | -0.37 | 0.79 | 0.05 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FAM154A | 0.08 | 0.04 | blup | 174 | 0.04 | 4.6e-05 | 5.32 | -5.5 | 4.0e-08 | -0.80 | 0.05 | 0.92 | FALSE |