TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Impedance of leg (left)
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chr9:18,355,044-19,844,265
Best TWAS P=8.75e-11 · Best GWAS P=1.27e-11 conditioned to 0.0248
18.4M
18.6M
18.8M
19M
19.2M
19.4M
19.6M
19.8M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Cells Transformed fibroblasts
PLIN2
0.08
0.02
lasso
4
0.03
1.5e-03
6.26
6.5
8.7e-11
0.88
0.04
0.90
TRUE
1
GTEx
Breast Mammary Tissue (Female)
HAUS6
0.13
0.01
lasso
1
0.00
4.2e-01
-0.41
-5.7
1.2e-08
-0.62
0.06
0.25
FALSE
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
FAM154A
0.08
0.04
blup
174
0.04
4.6e-05
5.32
-5.5
4.0e-08
-0.80
0.05
0.92
FALSE
3
GTEx
Esophagus Muscularis
HAUS6
0.22
0.09
lasso
4
0.11
4.6e-07
4.23
-5.3
1.2e-07
-0.37
0.79
0.05
FALSE