[Hub]/) : Traits : Impedance of leg (left) :

chr12:53,075,660-54,766,391

Best TWAS P=3e-10 · Best GWAS P=7.65e-10 conditioned to 0.00239

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PRR13 0.13 0.10 lasso 7 0.09 9.2e-08 -5.3 5.5 4.7e-08 -0.60 0.14 0.86 FALSE
2 GTEx Adipose Visceral Omentum PRR13 0.09 0.09 lasso 2 0.06 4.2e-04 -5.2 5.3 1.3e-07 -0.60 0.03 0.90 FALSE
3 GTEx Artery Aorta PRR13 0.23 0.28 enet 39 0.30 4.3e-17 -5.3 5.3 9.4e-08 -0.49 0.06 0.94 FALSE
4 GTEx Artery Tibial PRR13 0.15 0.18 enet 21 0.22 5.4e-17 -5.3 5.2 1.7e-07 -0.49 0.05 0.95 FALSE
5 GTEx Brain Cerebellum PRR13 0.19 0.02 enet 5 0.03 4.6e-02 -5.6 -5.5 2.9e-08 0.62 0.04 0.67 FALSE
6 GTEx Brain Putamen basal ganglia ATP5G2 0.26 0.26 lasso 6 0.21 1.0e-05 -5.9 -5.9 3.6e-09 0.98 0.01 0.98 FALSE
7 GTEx Esophagus Gastroesophageal Junction PRR13 0.22 0.16 lasso 4 0.18 3.2e-07 -5.3 5.6 2.5e-08 -0.46 0.03 0.89 FALSE
8 GTEx Esophagus Muscularis PRR13 0.13 0.15 lasso 2 0.14 9.2e-09 -5.3 5.5 4.2e-08 -0.55 0.05 0.95 FALSE
9 GTEx Nerve Tibial PRR13 0.17 0.21 lasso 3 0.20 2.7e-14 -5.3 5.2 2.0e-07 -0.56 0.05 0.95 FALSE
10 GTEx Ovary ATP5G2 0.41 0.29 lasso 12 0.28 1.7e-07 -4.6 -5.2 2.2e-07 0.93 0.01 0.98 FALSE
11 GTEx Skin Not Sun Exposed Suprapubic PRR13 0.17 0.09 lasso 4 0.09 1.6e-05 -5.2 5.4 8.2e-08 -0.60 0.04 0.96 FALSE
12 GTEx Thyroid SP1 0.11 0.05 lasso 7 0.04 8.2e-04 -5.5 -5.4 6.9e-08 0.63 0.05 0.93 FALSE
13 The Cancer Genome Atlas Bladder Urothelial Carcinoma PRR13 0.13 0.04 blup 28 0.07 3.3e-06 -4.1 5.3 9.3e-08 -0.44 0.03 0.72 FALSE
14 The Cancer Genome Atlas Colon Adenocarcinoma ATP5G2 0.07 0.06 lasso 2 0.06 4.0e-04 -5.9 -6.1 1.3e-09 0.94 0.00 0.99 FALSE
15 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PRR13 0.05 0.03 blup 28 0.04 4.1e-03 -5.3 5.8 8.6e-09 -0.65 0.01 0.67 FALSE
16 The Cancer Genome Atlas Brain Lower Grade Glioma PRR13 0.07 0.04 blup 28 0.05 4.7e-06 -5.3 5.9 4.0e-09 -0.61 0.01 0.97 FALSE
17 The Cancer Genome Atlas Rectum Adenocarcinoma PCBP2 0.25 0.04 blup 36 0.10 2.3e-03 4.6 6.1 8.6e-10 -0.69 0.01 0.25 FALSE
18 The Cancer Genome Atlas Thyroid Carcinoma PCBP2 0.04 0.01 enet 6 0.02 4.8e-03 -4.6 6.3 3.0e-10 -0.59 0.01 0.22 TRUE