[Hub]/) : Traits : Impedance of leg (left) : ← →

chr14:90,643,934-94,495,324

Best TWAS P=5.99e-28 · Best GWAS P=6.64e-28 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Colon Sigmoid	RIN3	0.24	0.17	lasso	6	0.11	9.3e-05	-10.9	11.0	6.0e-28	-1.00	0.00	1.00	TRUE
3	GTEx	Cells Transformed fibroblasts	RPS6KA5	0.08	0.07	lasso	2	0.06	5.3e-05	7.6	-7.9	3.8e-15	0.00	0.01	0.98	TRUE
15	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	BTBD7	0.02	0.01	blup	72	0.02	6.8e-03	6.8	-6.2	6.5e-10	0.01	0.01	0.91	TRUE
12	NTR	Blood	BTBD7	0.02	0.03	lasso	2	0.02	6.1e-08	5.9	-6.0	1.8e-09	-0.03	0.87	0.13	TRUE
14	The Cancer Genome Atlas	Lung Adenocarcinoma	RIN3	0.05	0.00	blup	163	0.01	6.0e-02	3.6	5.8	7.9e-09	-0.12	0.03	0.04	TRUE
9	GTEx	Spleen	C14orf159	0.30	0.21	lasso	5	0.21	3.6e-06	6.5	-7.8	5.3e-15	0.03	0.10	0.25	FALSE
6	GTEx	Esophagus Muscularis	RIN3	0.17	0.05	lasso	6	0.06	1.6e-04	-8.5	7.8	5.4e-15	-0.47	0.04	0.83	FALSE
5	GTEx	Colon Sigmoid	RPS6KA5	0.16	0.09	lasso	5	0.08	7.1e-04	7.7	7.7	1.5e-14	-0.02	0.04	0.91	FALSE
11	METSIM	Adipose	C14orf159	0.04	0.00	blup	464	0.01	4.0e-03	5.6	-6.7	1.9e-11	0.01	0.06	0.79	FALSE
8	GTEx	Heart Left Ventricle	RPS6KA5	0.13	0.00	enet	38	0.02	2.2e-02	5.4	6.3	2.9e-10	-0.06	0.04	0.67	FALSE
16	The Cancer Genome Atlas	Testicular Germ Cell Tumors	BTBD7	0.11	0.03	blup	72	0.02	8.0e-02	6.6	-6.1	1.4e-09	-0.04	0.04	0.49	FALSE
1	CommonMind	Brain Pre-frontal Cortex	BTBD7	0.04	0.04	lasso	2	0.03	1.8e-04	5.9	-5.9	3.0e-09	-0.05	0.70	0.25	FALSE
7	GTEx	Heart Atrial Appendage	C14orf159	0.18	0.10	lasso	4	0.06	1.6e-03	5.3	5.8	5.1e-09	-0.03	0.11	0.69	FALSE
2	GTEx	Cells Transformed fibroblasts	BTBD7	0.16	0.01	lasso	8	0.04	3.6e-04	6.6	-5.7	1.4e-08	-0.02	0.06	0.92	FALSE
13	YFS	Blood	RPS6KA5	0.11	0.03	enet	59	0.07	4.0e-21	5.4	5.4	8.4e-08	-0.03	0.95	0.05	FALSE
10	GTEx	Testis	BTBD7	0.19	0.00	enet	45	0.01	9.5e-02	5.4	-5.3	1.3e-07	-0.03	0.14	0.63	FALSE