[Hub]/) : Traits : Impedance of leg (left) :

chr14:90,643,934-94,495,324

Best TWAS P=5.99e-28 · Best GWAS P=6.64e-28 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex BTBD7 0.04 0.04 lasso 2 0.03 1.8e-04 5.9 -5.9 3.0e-09 -0.05 0.70 0.25 FALSE
2 GTEx Cells Transformed fibroblasts BTBD7 0.16 0.01 lasso 8 0.04 3.6e-04 6.6 -5.7 1.4e-08 -0.02 0.06 0.92 FALSE
3 GTEx Cells Transformed fibroblasts RPS6KA5 0.08 0.07 lasso 2 0.06 5.3e-05 7.6 -7.9 3.8e-15 0.00 0.01 0.98 TRUE
4 GTEx Colon Sigmoid RIN3 0.24 0.17 lasso 6 0.11 9.3e-05 -10.9 11.0 6.0e-28 -1.00 0.00 1.00 TRUE
5 GTEx Colon Sigmoid RPS6KA5 0.16 0.09 lasso 5 0.08 7.1e-04 7.7 7.7 1.5e-14 -0.02 0.04 0.91 FALSE
6 GTEx Esophagus Muscularis RIN3 0.17 0.05 lasso 6 0.06 1.6e-04 -8.5 7.8 5.4e-15 -0.47 0.04 0.83 FALSE
7 GTEx Heart Atrial Appendage C14orf159 0.18 0.10 lasso 4 0.06 1.6e-03 5.3 5.8 5.1e-09 -0.03 0.11 0.69 FALSE
8 GTEx Heart Left Ventricle RPS6KA5 0.13 0.00 enet 38 0.02 2.2e-02 5.4 6.3 2.9e-10 -0.06 0.04 0.67 FALSE
9 GTEx Spleen C14orf159 0.30 0.21 lasso 5 0.21 3.6e-06 6.5 -7.8 5.3e-15 0.03 0.10 0.25 FALSE
10 GTEx Testis BTBD7 0.19 0.00 enet 45 0.01 9.5e-02 5.4 -5.3 1.3e-07 -0.03 0.14 0.63 FALSE
11 METSIM Adipose C14orf159 0.04 0.00 blup 464 0.01 4.0e-03 5.6 -6.7 1.9e-11 0.01 0.06 0.79 FALSE
12 NTR Blood BTBD7 0.02 0.03 lasso 2 0.02 6.1e-08 5.9 -6.0 1.8e-09 -0.03 0.87 0.13 TRUE
13 YFS Blood RPS6KA5 0.11 0.03 enet 59 0.07 4.0e-21 5.4 5.4 8.4e-08 -0.03 0.95 0.05 FALSE
14 The Cancer Genome Atlas Lung Adenocarcinoma RIN3 0.05 0.00 blup 163 0.01 6.0e-02 3.6 5.8 7.9e-09 -0.12 0.03 0.04 TRUE
15 The Cancer Genome Atlas Lung Squamous Cell Carcinoma BTBD7 0.02 0.01 blup 72 0.02 6.8e-03 6.8 -6.2 6.5e-10 0.01 0.01 0.91 TRUE
16 The Cancer Genome Atlas Testicular Germ Cell Tumors BTBD7 0.11 0.03 blup 72 0.02 8.0e-02 6.6 -6.1 1.4e-09 -0.04 0.04 0.49 FALSE