[Hub]/) : Traits : Impedance of leg (left) : ← →

chr14:103,161,201-104,892,153

Best TWAS P=3.28e-10 · Best GWAS P=6.53e-10 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
32	The Cancer Genome Atlas	Prostate Adenocarcinoma	MARK3	0.07	0.06	enet	7	0.08	1.0e-08	6.2	6.3	3.3e-10	0.95	0.00	1.00	TRUE
8	GTEx	Breast Mammary Tissue (Male)	MARK3	0.08	0.00	enet	9	-0.01	7.2e-01	5.3	6.2	4.3e-10	0.66	0.03	0.38	FALSE
19	GTEx	Skin Not Sun Exposed Suprapubic	CKB	0.28	0.26	lasso	4	0.25	6.4e-14	6.1	6.2	7.3e-10	0.98	0.00	1.00	FALSE
25	YFS	Blood	KLC1	0.01	0.01	blup	389	0.01	1.0e-03	4.5	-6.1	1.1e-09	-0.61	0.26	0.32	FALSE
21	GTEx	Skin Sun Exposed Lower leg	CKB	0.43	0.32	enet	16	0.34	5.9e-29	6.1	6.1	1.3e-09	0.96	0.00	1.00	FALSE
26	The Cancer Genome Atlas	Breast Invasive Carcinoma	CKB	0.06	0.03	lasso	3	0.03	2.5e-06	6.2	6.0	1.6e-09	0.98	0.00	1.00	FALSE
3	GTEx	Adrenal Gland	KLC1	0.15	0.03	lasso	3	0.06	4.6e-03	-4.8	-5.9	3.2e-09	-0.52	0.12	0.25	FALSE
5	GTEx	Artery Tibial	TRMT61A	0.07	0.07	lasso	3	0.06	2.4e-05	5.1	5.9	4.3e-09	0.84	0.02	0.98	FALSE
14	GTEx	Lung	MARK3	0.06	0.02	lasso	3	0.01	6.6e-02	5.3	5.8	6.8e-09	0.77	0.04	0.90	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	MARK3	0.10	0.03	blup	61	0.03	4.0e-04	6.1	5.7	9.2e-09	0.74	0.01	0.76	FALSE
15	GTEx	Lung	CKB	0.07	0.01	lasso	2	0.01	3.4e-02	5.0	5.6	2.1e-08	0.71	0.07	0.80	FALSE
31	The Cancer Genome Atlas	Prostate Adenocarcinoma	C14orf153	0.09	0.08	blup	38	0.09	6.2e-10	4.9	5.6	2.2e-08	0.64	0.02	0.98	FALSE
2	GTEx	Adipose Visceral Omentum	KLC1	0.06	0.02	lasso	2	0.00	2.2e-01	5.0	-5.5	2.9e-08	-0.57	0.15	0.08	FALSE
10	GTEx	Cells Transformed fibroblasts	APOPT1	0.14	0.12	lasso	3	0.10	6.4e-08	4.9	5.5	3.0e-08	0.57	0.63	0.37	FALSE
28	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MARK3	0.07	0.03	blup	64	0.06	5.5e-07	6.1	5.5	3.3e-08	0.85	0.00	0.99	FALSE
16	GTEx	Pituitary	MARK3	0.21	0.27	enet	8	0.25	4.9e-07	5.3	5.5	3.4e-08	0.70	0.13	0.79	FALSE
4	GTEx	Artery Aorta	KLC1	0.10	0.14	lasso	3	0.14	6.1e-08	5.0	-5.5	3.8e-08	-0.59	0.57	0.42	FALSE
13	GTEx	Esophagus Muscularis	KLC1	0.07	0.01	enet	10	0.02	2.6e-02	5.0	-5.4	5.5e-08	-0.58	0.10	0.53	FALSE
18	GTEx	Skin Not Sun Exposed Suprapubic	MARK3	0.16	0.10	lasso	3	0.10	6.7e-06	5.3	5.4	5.8e-08	0.67	0.16	0.83	FALSE
20	GTEx	Skin Sun Exposed Lower leg	MARK3	0.10	0.09	enet	13	0.08	7.5e-07	5.2	5.4	7.9e-08	0.76	0.16	0.84	FALSE
11	GTEx	Esophagus Mucosa	KLC1	0.17	0.09	lasso	5	0.12	1.6e-08	-4.8	-5.3	8.9e-08	-0.42	0.84	0.14	FALSE
23	GTEx	Stomach	TRMT61A	0.12	0.11	lasso	5	0.08	1.2e-04	5.3	5.3	8.9e-08	0.69	0.12	0.78	FALSE
6	GTEx	Breast Mammary Tissue	MARK3	0.12	0.11	lasso	2	0.08	3.9e-05	5.3	5.3	9.2e-08	0.69	0.14	0.79	FALSE
24	GTEx	Thyroid	MARK3	0.38	0.48	lasso	4	0.48	2.8e-41	5.3	5.3	1.0e-07	0.69	0.20	0.80	FALSE
22	GTEx	Stomach	MARK3	0.10	0.09	lasso	2	0.04	4.5e-03	5.3	5.3	1.2e-07	0.68	0.16	0.53	FALSE
30	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	BAG5	0.08	0.09	lasso	2	0.08	3.7e-04	5.3	5.3	1.2e-07	0.69	0.00	0.96	FALSE
29	The Cancer Genome Atlas	Lung Adenocarcinoma	C14orf153	0.06	0.02	blup	38	0.04	2.4e-05	4.8	5.3	1.4e-07	0.54	0.03	0.86	FALSE
27	The Cancer Genome Atlas	Glioblastoma Multiforme	C14orf153	0.14	0.01	blup	40	0.03	3.5e-02	4.8	5.2	1.8e-07	0.73	0.00	0.45	FALSE
17	GTEx	Prostate	MARK3	0.18	0.22	enet	11	0.20	8.0e-06	5.3	5.2	2.0e-07	0.69	0.18	0.63	FALSE
7	GTEx	Breast Mammary Tissue	KLC1	0.12	0.02	enet	26	0.07	2.9e-04	-4.5	-5.2	2.1e-07	-0.41	0.84	0.05	FALSE
12	GTEx	Esophagus Muscularis	ZFYVE21	0.11	0.06	lasso	5	0.05	5.7e-04	4.8	-5.2	2.3e-07	-0.61	0.41	0.34	FALSE
1	GTEx	Adipose Subcutaneous	MARK3	0.12	0.05	lasso	3	0.06	2.5e-05	5.2	5.1	2.7e-07	0.69	0.16	0.81	FALSE
9	GTEx	Cells Transformed fibroblasts	ZFYVE21	0.10	0.03	lasso	4	0.11	1.1e-08	5.1	-5.1	2.7e-07	-0.56	0.29	0.49	FALSE