Best TWAS P=6.71e-10 · Best GWAS P=1.37e-12 conditioned to 2.37e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | LOXL1-AS1 | 0.28 | 0.09 | lasso | 6 | 0.17 | 1.7e-12 | 3.6 | 5.7 | 9.9e-09 | -0.64 | 0.96 | 0.04 | FALSE |
2 | GTEx | Testis | LOXL1-AS1 | 0.36 | 0.15 | lasso | 10 | 0.13 | 2.4e-06 | -6.1 | -6.2 | 6.7e-10 | 0.60 | 0.30 | 0.45 | TRUE |