Best TWAS P=1.42e-08 · Best GWAS P=6.91e-09 conditioned to 0.015
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Female) | HAGH | 0.13 | 0.00 | enet | 11 | 0.01 | 2.0e-01 | 4.6 | 5.2 | 2.2e-07 | -0.35 | 0.10 | 0.20 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | IFT140 | 0.11 | 0.02 | bslmm | 498 | 0.07 | 5.9e-09 | 1.3 | 5.7 | 1.4e-08 | -0.73 | 0.18 | 0.81 | TRUE |
| 3 | YFS | Blood | CRAMP1L | 0.02 | 0.01 | lasso | 5 | 0.01 | 1.6e-04 | -4.3 | -5.4 | 5.4e-08 | 0.77 | 0.41 | 0.56 | FALSE |
| 4 | YFS | Blood | FAHD1 | 0.04 | 0.04 | lasso | 6 | 0.04 | 1.3e-13 | 4.8 | 5.3 | 1.1e-07 | -0.27 | 0.51 | 0.48 | FALSE |
| 5 | The Cancer Genome Atlas | Esophageal Carcinoma | CRAMP1L | 0.11 | 0.08 | blup | 60 | 0.07 | 2.2e-03 | -4.3 | -5.2 | 1.6e-07 | 0.87 | 0.02 | 0.84 | FALSE |