[Hub]/) : Traits : Impedance of leg (left) : ← →

chr1:204,982,713-206,329,620

Best TWAS P=2.41e-08 · Best GWAS P=3.4e-07 conditioned to 0.982

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Stomach	NUCKS1	0.21	0.11	lasso	8	0.15	1.1e-07	5.1	-5.6	2.4e-08	-0.92	0.01	0.99	TRUE
6	GTEx	Pancreas	NUCKS1	0.16	0.00	lasso	4	0.00	4.5e-01	-4.8	-5.3	1.0e-07	-0.85	0.02	0.78	FALSE
5	GTEx	Nerve Tibial	SLC41A1	0.12	0.02	lasso	4	0.05	2.5e-04	4.7	5.3	1.2e-07	0.81	0.02	0.97	FALSE
1	GTEx	Esophagus Mucosa	NUCKS1	0.12	0.11	enet	6	0.06	7.2e-05	-4.9	-5.3	1.3e-07	-0.77	0.01	0.98	FALSE
2	GTEx	Esophagus Muscularis	NUCKS1	0.21	0.22	lasso	5	0.20	3.6e-12	5.1	-5.3	1.3e-07	-0.98	0.01	0.99	FALSE
7	GTEx	Pituitary	NUCKS1	0.26	0.19	lasso	2	0.20	7.6e-06	5.1	-5.2	1.6e-07	-1.00	0.01	0.97	FALSE
10	GTEx	Thyroid	NUCKS1	0.26	0.16	lasso	6	0.19	1.8e-14	4.8	-5.2	1.6e-07	-0.92	0.01	0.98	FALSE
3	GTEx	Heart Atrial Appendage	NUCKS1	0.12	0.14	enet	4	0.08	1.7e-04	-4.9	-5.2	1.7e-07	-0.80	0.01	0.96	FALSE
9	GTEx	Testis	NUCKS1	0.16	0.16	enet	15	0.16	1.3e-07	4.7	-5.2	1.7e-07	-0.89	0.01	0.98	FALSE
11	METSIM	Adipose	NUCKS1	0.05	0.02	lasso	6	0.01	4.3e-03	4.7	-5.2	1.7e-07	-0.88	0.01	0.97	FALSE
14	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RAB7L1	0.09	0.04	blup	46	0.04	1.2e-02	-4.8	5.2	2.0e-07	0.80	0.01	0.88	FALSE
12	YFS	Blood	RAB7L1	0.06	0.07	lasso	6	0.06	1.1e-19	-4.8	5.2	2.1e-07	0.79	0.01	0.98	FALSE
4	GTEx	Nerve Tibial	RAB7L1	0.35	0.14	enet	68	0.22	1.8e-15	-4.1	5.1	2.8e-07	0.58	0.07	0.90	FALSE
15	The Cancer Genome Atlas	Thyroid Carcinoma	RAB7L1	0.13	0.17	enet	15	0.21	3.6e-20	-4.9	5.1	2.9e-07	0.83	0.01	0.99	FALSE
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RAB7L1	0.09	0.08	enet	11	0.08	1.7e-09	-4.8	5.1	3.0e-07	0.74	0.01	0.98	FALSE