[Hub]/) : Traits : Impedance of leg (left) : ← →

chr1:204,982,713-206,329,620

Best TWAS P=2.41e-08 · Best GWAS P=3.4e-07 conditioned to 0.982

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Mucosa NUCKS1 0.12 0.11 enet 6 0.06 7.2e-05 -4.9 -5.3 1.3e-07 -0.77 0.01 0.98 FALSE
2 GTEx Esophagus Muscularis NUCKS1 0.21 0.22 lasso 5 0.20 3.6e-12 5.1 -5.3 1.3e-07 -0.98 0.01 0.99 FALSE
3 GTEx Heart Atrial Appendage NUCKS1 0.12 0.14 enet 4 0.08 1.7e-04 -4.9 -5.2 1.7e-07 -0.80 0.01 0.96 FALSE
4 GTEx Nerve Tibial RAB7L1 0.35 0.14 enet 68 0.22 1.8e-15 -4.1 5.1 2.8e-07 0.58 0.07 0.90 FALSE
5 GTEx Nerve Tibial SLC41A1 0.12 0.02 lasso 4 0.05 2.5e-04 4.7 5.3 1.2e-07 0.81 0.02 0.97 FALSE
6 GTEx Pancreas NUCKS1 0.16 0.00 lasso 4 0.00 4.5e-01 -4.8 -5.3 1.0e-07 -0.85 0.02 0.78 FALSE
7 GTEx Pituitary NUCKS1 0.26 0.19 lasso 2 0.20 7.6e-06 5.1 -5.2 1.6e-07 -1.00 0.01 0.97 FALSE
8 GTEx Stomach NUCKS1 0.21 0.11 lasso 8 0.15 1.1e-07 5.1 -5.6 2.4e-08 -0.92 0.01 0.99 TRUE
9 GTEx Testis NUCKS1 0.16 0.16 enet 15 0.16 1.3e-07 4.7 -5.2 1.7e-07 -0.89 0.01 0.98 FALSE
10 GTEx Thyroid NUCKS1 0.26 0.16 lasso 6 0.19 1.8e-14 4.8 -5.2 1.6e-07 -0.92 0.01 0.98 FALSE
11 METSIM Adipose NUCKS1 0.05 0.02 lasso 6 0.01 4.3e-03 4.7 -5.2 1.7e-07 -0.88 0.01 0.97 FALSE
12 YFS Blood RAB7L1 0.06 0.07 lasso 6 0.06 1.1e-19 -4.8 5.2 2.1e-07 0.79 0.01 0.98 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RAB7L1 0.09 0.08 enet 11 0.08 1.7e-09 -4.8 5.1 3.0e-07 0.74 0.01 0.98 FALSE
14 The Cancer Genome Atlas Pancreatic Adenocarcinoma RAB7L1 0.09 0.04 blup 46 0.04 1.2e-02 -4.8 5.2 2.0e-07 0.80 0.01 0.88 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma RAB7L1 0.13 0.17 enet 15 0.21 3.6e-20 -4.9 5.1 2.9e-07 0.83 0.01 0.99 FALSE