Hub : Genes

NUCKS1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.1050 0.0320 1.7e-05 0.103 NA 0.035 NA 0.075 8.8e-09 NA 7.4e-04 NA 9.4e-07
2 GTEx Adrenal Gland 0.1687 0.0678 7.5e-03 0.005 NA 0.019 NA 0.010 2.1e-01 NA 6.7e-02 NA 1.4e-01
3 GTEx Artery Aorta 0.1420 0.0470 3.9e-04 0.107 NA 0.069 NA 0.080 1.6e-06 NA 1.2e-04 NA 3.7e-05
4 GTEx Artery Tibial 0.1308 0.0439 2.5e-04 0.027 NA 0.004 NA 0.011 3.3e-03 NA 1.5e-01 NA 4.0e-02
5 GTEx Brain Caudate basal ganglia 0.2520 0.0970 6.5e-03 0.235 NA 0.131 NA 0.250 2.3e-07 NA 1.4e-04 NA 8.1e-08
6 GTEx Brain Cerebellum 0.2220 0.0760 1.4e-03 0.128 NA 0.050 NA 0.082 1.3e-04 NA 1.4e-02 NA 2.0e-03
7 GTEx Brain Hippocampus 0.5709 0.1353 2.0e-03 0.030 NA 0.093 NA 0.110 6.7e-02 NA 3.4e-03 NA 1.6e-03
8 GTEx Brain Putamen basal ganglia 0.4040 0.1180 1.4e-03 0.260 NA 0.251 NA 0.274 7.1e-07 NA 1.1e-06 NA 3.2e-07
9 GTEx Breast Mammary Tissue 0.1450 0.0520 6.0e-04 0.053 NA 0.079 NA 0.089 1.0e-03 NA 7.4e-05 NA 2.5e-05
10 GTEx Colon Sigmoid 0.3440 0.1090 1.5e-04 0.220 NA 0.206 NA 0.196 2.6e-08 NA 8.3e-08 NA 1.7e-07
11 GTEx Esophagus Mucosa 0.1210 0.0390 1.1e-04 0.106 NA 0.060 NA 0.034 1.4e-07 NA 7.2e-05 NA 2.3e-03
12 GTEx Esophagus Muscularis 0.2110 0.0520 7.3e-08 0.219 NA 0.189 NA 0.198 2.1e-13 NA 1.2e-11 NA 3.6e-12
13 GTEx Heart Atrial Appendage 0.1210 0.0500 6.0e-03 0.137 NA 0.081 NA 0.026 1.0e-06 NA 1.7e-04 NA 2.4e-02
14 GTEx Heart Left Ventricle 0.1041 0.0437 5.2e-03 0.045 NA 0.011 NA 0.048 2.1e-03 NA 7.8e-02 NA 1.4e-03
15 GTEx Lung 0.0943 0.0311 2.9e-04 0.069 NA 0.019 NA 0.044 5.3e-06 NA 1.3e-02 NA 2.6e-04
16 GTEx Nerve Tibial 0.2457 0.0480 7.8e-12 0.212 NA 0.224 NA 0.216 5.7e-15 NA 7.3e-16 NA 2.9e-15
17 GTEx Pancreas 0.1570 0.0650 6.7e-03 -0.001 NA -0.004 NA -0.003 3.7e-01 NA 5.1e-01 NA 4.5e-01
18 GTEx Pituitary 0.2630 0.1070 4.2e-03 0.193 NA 0.136 NA 0.204 1.4e-05 NA 2.8e-04 NA 7.6e-06
19 GTEx Prostate 0.3780 0.1000 2.1e-04 0.226 NA 0.153 NA 0.322 2.3e-06 NA 1.1e-04 NA 7.5e-09
20 GTEx Skin Not Sun Exposed Suprapubic 0.1990 0.0620 6.3e-05 0.135 NA 0.093 NA 0.126 7.3e-08 NA 8.9e-06 NA 2.0e-07
21 GTEx Skin Sun Exposed Lower leg 0.2020 0.0380 2.4e-15 0.264 NA 0.235 NA 0.260 7.3e-22 NA 2.5e-19 NA 1.5e-21
22 GTEx Spleen 0.2380 0.1040 7.4e-03 0.038 NA 0.099 NA 0.083 3.9e-02 NA 1.6e-03 NA 3.8e-03
23 GTEx Stomach 0.2080 0.0600 1.8e-05 0.110 NA 0.141 NA 0.150 6.3e-06 NA 3.1e-07 NA 1.2e-07
24 GTEx Testis 0.1570 0.0490 1.4e-04 0.162 NA 0.161 NA 0.157 1.1e-07 NA 1.3e-07 NA 1.7e-07
25 GTEx Thyroid 0.2590 0.0520 1.5e-11 0.160 NA 0.185 NA 0.190 3.0e-12 NA 4.1e-14 NA 1.8e-14
26 METSIM Adipose 0.0490 0.0202 1.9e-03 0.024 0.007 0.012 0.008 0.013 1.4e-04 2.5e-02 5.7e-03 2.2e-02 4.3e-03
27 YFS Blood 0.1484 0.0223 0.0e+00 0.235 0.217 0.243 0.240 0.249 9.4e-76 2.3e-69 1.1e-78 1.6e-77 1.4e-80
28 TCGA Breast Invasive Carcinoma 0.0272 0.0150 9.4e-04 0.001 0.010 0.008 NA 0.006 2.0e-01 3.5e-03 7.1e-03 NA 1.6e-02
29 TCGA Prostate Adenocarcinoma 0.0377 0.0203 6.8e-04 0.053 0.024 0.025 NA 0.034 2.9e-06 1.2e-03 9.8e-04 NA 1.5e-04
30 TCGA Thyroid Carcinoma 0.0680 0.0260 6.7e-07 0.073 0.073 0.072 NA 0.069 1.3e-07 1.3e-07 1.6e-07 NA 2.9e-07
31 TCGA Uterine Corpus Endometrial Carcinoma 0.1140 0.0610 3.7e-03 0.017 0.088 0.044 NA 0.033 1.1e-01 1.9e-03 2.3e-02 NA 4.1e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31
Bipolar Disorder (2018) 1.9 3.0 6.7 -1.6 -1.9 -2.1 -1.8 2.2 -1.5 -2.2 -1.7 -1.8 -2.6 -1.5 -1.9 -2.0 -1.8 -1.9 -2.0 -1.3 -1.9 1.1 -1.8 -1.8 0.6 -1.2 -1.2 -2.0 -1.5 -2.0 0.4 -1.8 -1.0 -1.6
Bipolar Disorder or Schizophrenia 1.4 3.5 7.3 -2.0 -2.7 -1.9 -2.0 1.3 -1.8 -2.6 -2.0 -1.9 -2.7 -0.9 -2.2 -1.5 -2.5 -2.5 -2.2 -1.5 -2.3 0.8 -2.1 -2.1 -0.1 -1.3 -1.4 -1.9 -1.6 -1.9 -0.2 -1.8 -1.3 -1.2
Depressed Affect (Nagel 2018) 3.1 6.5 12.5 -2.8 -3.1 -2.6 -3.1 1.8 -2.8 -3.3 -2.8 -2.5 -3.5 -1.8 -2.9 -2.2 -2.8 -2.9 -3.1 -2.1 -2.9 1.4 -2.9 -2.8 -1.6 -2.1 -2.5 -2.7 -2.1 -2.6 -1.2 -2.5 -2.0 -1.5
Depression (Nagel 2018) 0.6 0.8 3.3 0.7 -0.2 0.8 -0.6 -1.4 0.2 -1.3 0.6 1.3 -0.1 1.6 0.8 1.4 0.5 0.6 0.5 1.1 0.8 -0.9 0.7 0.6 0.4 1.3 0.4 0.8 0.9 1.0 0.6 0.7 0.4 1.8
Intelligence (Savage-Jansen 2018) 1.0 3.1 9.9 1.1 2.3 2.0 2.0 -2.4 1.8 3.1 1.1 0.5 1.5 2.2 1.8 2.4 1.5 1.5 1.9 2.2 1.5 -0.9 1.3 1.2 2.1 1.6 1.5 2.1 2.0 1.8 1.3 1.1 0.6 1.6
Neuroticism (Nagel 2018) 2.9 6.7 11.2 -2.7 -2.7 -2.8 -3.0 1.8 -2.7 -3.3 -2.8 -2.5 -3.1 -2.2 -3.0 -2.5 -2.6 -2.9 -3.1 -2.6 -3.1 1.8 -2.9 -2.7 -1.5 -2.5 -2.6 -2.8 -2.6 -2.7 -1.4 -2.4 -1.5 -2.2
Schizophrenia (2018) 0.6 1.2 3.6 -1.3 -1.9 -0.7 -1.1 -0.2 -1.1 -1.6 -1.2 -1.0 -1.4 0.1 -1.3 -0.3 -1.8 -1.6 -1.2 -0.9 -1.4 0.2 -1.3 -1.3 -0.7 -0.7 -0.8 -0.9 -0.8 -0.9 -0.6 -0.9 -0.9 -0.2
Schizophrenia vs Biploar Disorder 0.7 0.9 2.0 0.9 0.3 1.1 1.2 -1.3 0.6 -0.6 1.0 1.2 0.8 1.1 0.9 1.2 1.0 1.0 0.7 0.9 1.0 -0.9 1.0 1.1 -0.9 0.9 0.6 1.1 0.8 1.1 -0.4 1.4 1.0 0.7
Worry (Nagel 2018) 3.9 8.2 11.9 -2.8 -2.4 -3.3 -3.2 2.4 -3.0 -3.5 -2.8 -2.6 -3.0 -2.6 -3.3 -3.0 -3.2 -2.9 -3.3 -3.4 -3.4 1.6 -3.0 -2.9 -1.4 -3.0 -2.9 -3.3 -3.0 -3.0 -2.3 -2.9 -1.2 -2.8
Alzheimer’s Disease (in mother) 0.3 0.3 0.7 -0.7 -0.3 -0.7 -0.5 0.2 -0.8 0.3 -0.7 -0.8 -0.5 -0.3 -0.7 -0.4 0.1 -0.5 -0.3 -0.6 -0.7 0.8 -0.8 -0.6 -0.7 -0.6 -0.3 -0.6 -0.5 -0.7 -0.4 -0.5 -0.8 -0.8
Alzheimer’s Disease (in father) 4.4 4.8 10.2 -2.5 -2.7 -1.6 -2.1 1.4 -2.4 -1.6 -2.4 -2.7 -3.2 -1.4 -2.1 -1.5 -2.6 -2.6 -2.2 -1.0 -2.4 1.4 -2.5 -2.5 -2.8 -1.7 -2.5 -2.0 -2.3 -2.2 -0.2 -2.0 -2.7 -1.8
Alzheimer’s Disease (including proxy) 1.4 2.0 4.4 -1.7 -1.4 -1.1 -1.5 0.8 -1.8 -0.7 -1.8 -2.1 -1.9 -0.8 -1.2 -0.9 -1.2 -1.8 -1.2 -0.6 -1.4 1.2 -1.7 -1.6 -1.6 -1.0 -1.5 -1.2 -1.5 -1.5 0.2 -1.4 -1.8 -1.8
Crohns Disease (2017) 2.0 4.4 6.7 -2.0 -1.3 -2.4 -1.9 2.3 -2.0 -1.9 -2.0 -1.8 -1.8 -2.2 -2.4 -2.4 -2.4 -2.2 -2.3 -2.6 -2.5 1.5 -2.2 -2.1 -1.5 -2.6 -1.8 -2.3 -2.0 -2.2 -1.7 -2.3 -1.5 -2.1
Irritable Bowel Disease (IBD) 4.1 9.7 16.2 -3.0 -2.7 -3.3 -2.8 3.8 -3.0 -2.8 -2.8 -2.8 -2.4 -3.9 -3.4 -4.0 -3.1 -2.9 -3.2 -3.7 -3.4 3.0 -3.1 -3.0 -1.7 -3.6 -2.9 -3.5 -3.2 -3.5 -1.2 -2.9 -2.4 -3.6
Ulcerative Colitis (UC) 5.6 10.5 19.5 -3.2 -2.9 -3.3 -2.9 4.1 -3.2 -2.6 -2.9 -3.1 -2.2 -4.4 -3.2 -4.4 -2.7 -3.0 -3.2 -3.7 -3.2 3.6 -3.2 -3.1 -1.3 -3.5 -3.3 -3.8 -3.5 -3.7 -0.5 -2.8 -2.7 -4.0
Major Depression (MDD) 1.5 1.8 4.0 -1.8 -1.2 -1.1 -1.3 0.5 -1.3 -1.1 -1.8 -1.3 -1.2 -0.9 -1.4 -0.9 -1.8 0.0 -1.3 -1.1 -1.3 1.5 -1.7 -1.8 -0.7 -1.0 -1.5 -1.3 -1.3 -1.4 -1.6 -1.7 -2.0 -0.0
Reaction Time 8.4 16.1 29.1 -4.0 -3.0 -4.2 -4.8 3.9 -4.5 -3.6 -4.1 -3.8 -3.2 -4.1 -4.2 -4.0 -3.6 -3.9 -4.0 -3.9 -4.0 5.4 -4.2 -4.0 -2.3 -4.2 -4.4 -4.4 -4.3 -4.4 -3.2 -4.0 -3.9 -4.0
Verbal and Numeric Reasoning (VNR) 1.2 2.8 5.6 1.2 1.9 2.2 1.8 -2.1 1.6 2.4 1.2 0.7 0.9 2.2 1.9 2.3 1.5 1.1 1.9 2.2 1.7 -1.4 1.4 1.1 1.5 1.9 1.5 2.1 2.1 1.8 1.7 0.7 0.5 1.7
Breast Cancer 1.1 2.6 4.8 -1.6 -1.8 -1.6 -1.0 2.1 -1.3 -0.8 -1.6 -2.2 -1.6 -1.7 -1.6 -1.8 -1.7 -1.5 -1.5 -1.7 -1.7 1.7 -1.7 -1.7 0.4 -1.6 -1.6 -1.7 -1.3 -1.7 0.5 -2.1 -2.0 -1.6
Ovarian Cancer 0.5 0.7 2.5 -0.8 -0.2 -0.8 -0.5 0.4 -0.3 -0.9 -0.8 -0.3 -1.2 -0.5 -1.0 -0.4 -0.9 -1.1 -0.8 -0.8 -0.9 0.9 -0.9 -0.9 0.3 -0.9 -1.0 -0.6 -0.4 -0.6 -1.6 -1.0 -1.1 -0.1
Prostate Cancer 14.5 20.3 28.4 4.9 3.2 4.3 4.9 -4.1 5.0 3.3 4.7 4.5 3.6 4.3 4.6 4.1 5.3 4.6 4.7 4.9 4.3 -4.4 4.8 5.0 4.6 4.6 4.7 4.8 4.7 4.9 3.9 4.9 4.7 3.8
Age at First Birth 0.1 0.2 1.5 0.1 -1.2 0.1 -0.3 0.5 -0.3 0.8 0.2 0.0 -0.5 -0.8 -0.2 -0.8 -0.2 0.2 -0.0 -0.3 0.0 0.9 -0.0 0.0 0.7 -0.1 0.0 -0.5 -0.6 -0.1 -0.1 -0.1 -0.5 -0.1
Bipolar Disorder (2011) 3.3 3.2 6.2 -1.9 -1.6 -2.3 -2.1 0.0 -1.7 -1.5 -2.0 -2.4 -1.8 -1.7 -2.2 -2.1 -2.2 0.0 -2.2 -2.5 -2.2 1.7 -2.0 -2.0 -0.3 -1.7 -1.4 -2.1 -1.9 -2.1 -0.4 0.0 -1.0 -1.7
Body Mass Index (BMI) (2010) 6.8 9.3 15.2 3.1 2.2 3.2 3.5 -2.2 3.6 2.3 3.2 3.1 3.1 2.7 3.3 2.7 3.5 2.6 3.4 3.3 3.2 -3.3 3.2 3.3 2.3 3.1 3.1 3.3 2.7 3.0 2.3 3.9 3.5 2.4
Coronary Artery Disease (CAD) 1.5 1.8 4.2 1.3 1.5 1.3 1.7 -0.7 1.6 1.6 1.3 1.6 1.4 1.1 1.2 1.1 1.5 0.0 1.6 1.0 1.3 -1.8 1.3 1.2 1.3 1.2 1.8 1.3 1.6 1.3 -0.3 1.3 1.1 2.0
Crohns Disease (2012) 3.9 6.3 10.3 -2.6 -1.3 -3.0 -1.8 3.2 -2.1 -2.0 -2.6 -2.4 -2.1 -2.9 -2.8 -3.0 -3.2 0.0 -2.7 -3.1 -2.8 2.1 -2.7 -2.7 -1.2 -3.0 -2.4 -2.7 -2.6 -2.9 -1.9 -2.8 -2.3 -2.4
Mean Putamen Volume 0.8 0.9 2.4 -1.0 -0.6 -0.8 -1.4 0.3 -1.0 -0.2 -1.1 -0.9 -1.4 -0.2 -1.0 -0.2 -1.5 -0.8 -0.9 -0.5 -1.2 0.6 -1.1 -1.1 -0.3 -1.2 -1.1 -0.7 -0.8 -0.7 -0.8 -1.3 -1.0 -0.6
Fasting Glucose 2.2 2.7 5.9 1.5 0.1 2.2 0.8 -1.1 1.3 -0.6 1.6 1.9 1.5 2.0 1.9 1.8 1.1 1.3 1.6 1.3 2.0 -1.8 1.7 1.6 -0.2 2.3 2.3 1.7 2.0 1.6 2.1 1.7 0.5 2.4
HbA1C 4.5 5.0 10.6 2.4 2.9 1.9 2.4 -1.7 2.7 1.5 2.1 2.8 2.7 1.9 2.2 2.1 2.9 2.0 2.2 2.1 2.4 -1.6 2.4 2.5 -0.1 2.1 2.0 2.3 2.1 2.2 0.7 3.3 2.5 2.2
HDL Cholesterol 5.9 9.8 14.0 -3.1 -1.2 -3.4 -2.8 2.6 -3.2 -3.6 -3.1 -2.8 -2.6 -3.3 -3.5 -3.2 -2.9 -3.1 -3.4 -3.3 -3.6 3.3 -3.3 -3.1 -2.1 -3.7 -3.1 -3.4 -3.4 -3.1 -2.4 -3.6 -3.3 -3.5
LDL Cholesterol 0.2 0.3 0.8 0.4 0.1 0.4 0.8 -0.2 0.8 -0.2 0.3 0.3 0.6 0.4 0.3 0.2 0.8 0.4 0.4 0.4 0.2 -0.3 0.3 0.5 0.9 0.5 0.7 0.6 0.9 0.4 0.6 0.7 0.1 0.7
Lupus 3.3 5.0 7.5 -2.3 -1.6 -2.1 -1.4 2.3 -2.1 -2.2 -2.1 -2.7 -2.0 -2.4 -2.4 -2.3 -2.6 -2.2 -2.2 -2.1 -2.4 1.9 -2.3 -2.3 -1.8 -2.5 -2.7 -2.4 -2.5 -2.4 -1.5 -2.0 -2.2 -2.5
Neuroticism (2016) 0.2 0.2 1.6 -0.1 -0.1 0.1 -1.2 -0.0 -0.7 -1.3 0.0 0.4 -0.5 -0.6 0.1 -0.4 0.0 -0.2 -0.3 0.0 0.2 0.5 -0.0 -0.0 -0.5 0.1 -0.9 -0.4 -0.6 -0.2 -0.3 0.2 0.1 -0.3
Primary Biliary Cirrhosis 3.0 4.3 9.5 2.6 1.8 1.7 2.3 -0.9 2.1 1.2 2.6 3.1 2.5 1.1 2.1 1.2 1.9 2.9 1.8 1.1 2.4 -2.2 2.6 2.6 1.7 1.8 1.7 1.8 2.0 2.1 0.4 2.4 2.9 1.6
Rheumatoid Arthritis 1.7 2.4 4.1 -1.5 -0.8 -1.9 -1.0 1.4 -1.5 -0.8 -1.5 -1.2 -1.8 -1.7 -2.0 -1.8 -1.7 -1.6 -1.7 -1.5 -2.0 1.0 -1.7 -1.6 -1.0 -1.9 -1.6 -1.8 -1.7 -1.7 -1.0 -1.5 -1.0 -1.7
Schizophrenia (2014) 0.7 1.6 6.8 -1.3 -1.8 -0.9 -1.6 0.6 -1.5 -2.6 -1.2 -1.1 -2.0 -0.3 -1.4 -0.7 -1.9 -1.6 -1.5 -1.0 -1.6 0.4 -1.4 -1.4 -0.0 -0.9 -1.0 -1.2 -0.8 -1.1 -0.3 -1.1 -0.8 -0.6
Triglycerides 1.0 1.7 3.7 1.0 1.1 1.7 0.4 -1.7 1.0 1.3 1.0 1.3 1.7 1.8 1.4 1.8 1.2 1.2 1.5 1.2 1.4 -0.6 1.1 1.0 1.4 1.6 0.9 1.5 1.3 1.3 -0.1 1.5 0.7 1.9
Type 2 Diabetes (T2D) (2012) 3.0 3.5 6.4 2.2 1.7 2.1 1.4 -0.8 1.5 1.3 2.5 2.3 1.4 1.3 2.2 1.3 2.4 2.5 1.7 1.9 2.4 -1.9 2.4 2.2 1.0 2.3 1.3 1.5 1.5 1.9 2.0 1.7 2.4 0.1
Ulcerative Colitis 3.0 4.4 8.1 -2.1 -2.0 -1.9 -1.9 2.6 -2.0 -1.7 -2.0 -1.9 -1.2 -2.8 -2.0 -2.8 -1.7 -1.8 -2.0 -2.3 -2.1 2.5 -2.2 -2.1 -0.8 -2.2 -2.3 -2.3 -2.4 -2.4 0.1 -1.9 -2.1 -2.7
Blood Eosinophil Count 0.9 7.2 17.1 2.4 1.4 2.8 2.0 -2.0 2.7 -0.2 2.4 2.4 1.1 2.8 3.1 2.2 2.0 2.4 2.6 3.6 2.9 -3.1 2.6 2.5 2.6 3.8 3.3 2.7 3.2 2.5 4.1 3.0 3.2 2.6
Blood Platelet Count 0.2 2.9 13.0 0.2 3.2 -0.3 1.2 -3.6 1.3 1.3 -0.5 0.6 -0.3 2.9 1.0 2.5 0.1 -0.0 -0.3 1.3 1.0 -1.9 0.7 0.2 2.5 2.0 2.8 1.6 1.8 1.3 -0.8 1.1 1.7 2.7
Blood Red Count 0.1 0.9 5.0 0.9 1.0 1.8 0.8 -0.5 0.3 2.2 1.3 0.7 1.1 0.2 0.9 0.7 0.9 0.4 2.0 0.6 1.1 0.5 1.0 0.9 -1.0 0.2 -0.5 0.6 0.5 0.8 -1.0 0.3 0.5 0.1
Blood White Count 0.1 1.0 5.6 0.0 -0.8 0.6 -0.9 -1.5 -0.2 -1.1 0.0 1.0 -1.4 1.4 0.4 0.7 -0.6 0.2 0.0 1.2 0.6 -1.4 0.2 0.0 -2.0 1.8 1.2 0.2 1.2 0.5 0.5 0.6 0.4 2.4
Heel T-Score 0.3 2.1 3.9 1.8 1.4 1.7 1.1 -1.1 1.1 0.9 1.9 1.3 1.7 1.1 1.4 1.3 1.8 2.0 1.8 1.0 1.4 -1.1 1.7 1.7 2.0 1.0 1.2 1.4 1.3 1.7 0.0 1.5 0.8 1.6
BMI 2.2 13.0 20.2 3.5 1.9 4.0 4.2 -3.0 4.1 2.1 3.6 3.4 3.2 3.7 3.7 3.5 3.6 3.4 3.9 3.5 3.6 -4.5 3.7 3.7 2.1 3.9 3.7 4.0 4.1 3.9 2.6 4.2 3.1 4.3
Height 5.5 105.5 163.8 10.7 9.9 11.3 8.9 -12.7 9.9 8.1 10.1 10.3 10.6 12.1 10.9 12.8 10.7 10.4 10.9 10.8 10.7 -7.3 10.5 10.6 6.4 10.3 10.6 11.9 10.3 11.7 4.5 9.8 8.2 9.9
Waist Hip Ratio (WHR) 0.0 0.2 1.3 0.2 -0.3 0.6 -0.2 -1.2 -0.1 -1.0 0.3 0.2 -0.2 0.5 0.0 0.4 0.1 0.4 0.3 0.1 0.0 -0.4 0.1 0.1 -0.7 0.3 0.8 0.2 0.2 0.3 0.0 -0.3 -0.0 0.6
Systolic Blood Pressure 0.5 2.7 5.9 -1.5 -1.8 -1.5 -1.4 1.7 -1.4 -1.5 -1.3 -1.8 -1.7 -1.6 -2.0 -1.8 -1.7 -1.5 -1.3 -2.2 -2.1 0.8 -1.7 -1.5 -2.4 -2.0 -1.7 -1.9 -1.3 -1.7 -0.6 -1.6 -1.2 -1.5
Smoking Status 2.5 5.9 9.0 -2.4 -2.6 -2.3 -1.7 2.5 -2.0 -2.1 -2.3 -2.5 -2.1 -2.6 -2.8 -2.7 -3.0 -2.5 -2.4 -2.3 -3.0 1.9 -2.7 -2.4 -2.3 -2.9 -2.5 -2.4 -2.5 -2.5 -1.2 -2.3 -2.5 -2.4
Allergy or Eczema 0.7 1.7 9.2 1.6 1.8 1.3 1.5 -0.8 1.5 0.6 1.7 1.5 1.0 0.7 0.9 0.8 1.3 1.3 1.5 1.5 1.0 -0.3 1.3 1.5 3.0 0.7 1.5 1.2 1.0 1.4 0.3 1.1 0.4 1.3
Cardiovascular Disease 2.9 9.6 25.3 -3.4 -5.0 -2.9 -3.1 2.7 -3.1 -3.0 -3.2 -3.3 -3.6 -2.7 -3.2 -3.0 -3.6 -3.2 -3.3 -3.3 -3.0 1.8 -3.2 -3.4 -2.9 -2.7 -2.7 -3.3 -2.5 -3.2 -2.1 -3.4 -2.7 -2.0
Hypothyroidism (self reported) 0.5 1.1 4.8 -1.1 -0.5 -1.0 -0.3 0.7 -0.4 -0.3 -1.0 -1.1 -0.6 -0.8 -1.3 -0.7 -0.6 -1.1 -0.8 -1.0 -1.2 1.8 -1.2 -0.9 1.5 -1.4 -1.1 -0.8 -1.1 -0.9 -2.2 -0.4 -0.8 -0.7
Respiratory disease 0.3 0.6 1.1 0.6 -0.1 0.9 1.0 -0.9 0.9 1.1 0.5 0.1 0.3 1.0 0.8 1.0 0.8 0.7 0.6 1.1 0.8 -0.4 0.7 0.6 0.3 1.0 1.0 0.9 0.5 0.8 0.9 0.2 0.4 0.6
Type 2 Diabetes (T2D) (2018) 3.0 5.7 11.1 2.6 1.2 2.9 2.2 -2.7 2.5 1.8 2.7 2.6 2.1 2.8 1.9 2.7 2.6 2.6 2.6 2.3 1.9 -2.3 2.2 2.6 1.2 1.9 2.8 2.7 2.6 2.8 1.0 2.3 1.3 3.3
Lung FEV1/FVC ratio 6.9 35.1 71.6 5.2 5.0 6.4 5.2 -7.2 5.4 4.1 5.1 5.3 3.3 7.3 6.2 7.0 5.8 5.6 6.0 8.5 5.7 -6.9 5.5 5.5 3.5 6.9 6.3 6.7 6.6 6.2 4.4 6.5 4.5 6.3
Lung FVC 4.1 20.9 34.9 -4.5 -4.8 -5.7 -2.6 5.9 -3.1 -2.3 -4.5 -4.7 -3.3 -5.8 -4.8 -5.8 -4.9 -4.8 -5.0 -5.7 -4.6 3.7 -4.4 -4.6 -0.0 -5.1 -4.5 -5.1 -5.5 -5.2 -2.5 -4.7 -2.0 -5.6
Neuroticism 4.2 10.2 15.1 -3.0 -3.2 -3.5 -3.7 3.0 -3.4 -3.5 -2.9 -2.7 -3.9 -3.2 -3.9 -3.6 -3.2 -3.1 -3.7 -3.6 -3.8 1.8 -3.3 -3.0 -2.6 -3.3 -3.1 -3.8 -3.4 -3.3 -1.7 -2.8 -2.1 -2.7
Chronotype (morning person) 0.3 0.8 2.4 1.2 0.5 0.9 1.1 -0.2 1.0 0.3 1.4 1.0 0.9 0.2 0.6 0.2 1.5 1.5 0.7 0.4 0.7 -0.8 1.1 1.2 1.3 0.4 0.6 0.7 0.3 0.9 0.6 1.0 1.2 0.1
Hair Pigment 1.3 36.3 53.7 -6.1 -7.3 -7.3 -4.8 7.0 -5.7 -5.1 -6.4 -5.9 -6.3 -6.2 -6.3 -6.3 -6.5 -5.9 -7.2 -5.6 -6.3 4.9 -6.1 -6.0 -4.7 -6.2 -6.4 -6.3 -5.8 -6.4 -3.6 -5.8 -4.7 -6.2
Tanning 0.0 0.2 1.8 -0.4 1.3 -0.4 -0.2 -0.3 -0.3 -0.6 -0.5 -0.5 -0.1 -0.2 0.0 -0.2 0.2 -1.0 -0.2 0.3 0.2 0.7 -0.2 -0.3 0.5 0.3 0.5 -0.2 -0.0 -0.4 0.4 0.4 -0.5 0.3
Hand grip strength (left) 17.9 47.1 58.7 7.4 6.7 7.4 7.5 -6.4 7.2 6.2 7.4 6.7 6.5 7.0 7.1 7.0 7.2 7.0 7.5 6.8 6.8 -6.0 7.2 7.5 3.2 6.7 7.7 7.6 7.4 7.6 4.5 7.2 5.7 6.5
Number of treatments/medications taken 7.8 14.1 18.5 -4.0 -4.3 -4.2 -3.5 3.7 -3.6 -3.3 -4.0 -3.7 -3.8 -3.6 -4.0 -3.7 -4.2 -4.1 -4.2 -4.2 -3.7 3.4 -3.9 -4.0 -2.1 -3.6 -3.6 -4.1 -3.5 -4.0 -3.0 -4.1 -3.2 -2.7
Average weekly spirits intake 0.7 0.9 4.4 1.1 -0.8 0.1 1.2 0.5 1.1 0.1 1.0 0.8 0.8 0.3 0.6 -0.2 0.7 0.8 0.5 0.0 0.5 -2.1 1.0 1.1 0.3 0.8 1.3 0.5 1.0 0.6 2.0 1.1 1.4 0.6
Sensitivity / hurt feelings 1.3 2.2 3.9 -1.4 -1.1 -1.6 -1.4 1.4 -1.2 -0.0 -1.5 -1.5 -1.6 -1.8 -1.6 -1.8 -1.4 -1.6 -1.2 -1.7 -1.7 1.7 -1.6 -1.4 -2.0 -1.7 -1.9 -1.8 -1.4 -1.6 -0.6 -0.9 -0.8 -1.3
Frequency of depressed mood in last 2 weeks 0.2 0.3 3.2 -0.1 -0.1 -0.3 -1.5 0.5 -0.8 -1.8 -0.2 0.4 -0.5 -0.1 -0.2 -0.2 -0.9 -0.3 -0.5 -0.3 -0.2 0.5 -0.2 -0.3 -0.4 -0.0 -0.8 -0.5 -0.1 -0.2 0.4 -0.6 -0.5 0.2
Hearing difficulty/problems: Yes 5.2 8.0 12.5 3.2 2.8 3.2 1.9 -3.2 2.4 1.8 3.2 3.3 3.5 2.8 3.0 3.1 3.4 3.2 3.1 2.5 3.0 -2.9 3.1 3.2 0.6 2.6 2.4 3.0 2.3 3.2 1.1 3.3 2.9 2.3
Relative age of first facial hair 2.3 4.7 11.2 -2.5 -3.3 -2.2 -2.1 1.8 -2.1 -1.4 -2.4 -2.3 -1.7 -2.1 -1.9 -2.0 -2.4 -2.6 -2.2 -2.2 -2.1 1.4 -2.3 -2.4 -2.1 -2.2 -2.1 -2.0 -2.1 -2.3 -1.0 -2.4 -1.7 -2.7
Other serious medical condition/disability diagnosed by doctor 6.1 7.9 14.8 -2.5 -2.2 -3.3 -2.7 3.8 -2.3 -1.5 -2.5 -2.3 -1.6 -3.9 -2.8 -3.6 -3.0 -2.6 -2.7 -3.6 -2.3 3.2 -2.4 -2.6 -1.1 -3.0 -3.2 -3.4 -3.6 -3.2 -2.5 -2.4 -1.1 -3.3
Ever used hormone-replacement therapy (HRT) 0.2 0.2 1.3 0.2 -0.6 -0.3 0.2 0.7 -0.0 1.0 0.2 0.4 -0.3 -0.6 0.1 -0.6 0.2 0.1 0.1 -0.1 0.2 0.1 0.3 0.1 -0.2 -0.0 -0.7 -0.3 0.2 -0.1 0.3 -0.4 1.1 -0.9
Ever had hysterectomy (womb removed) 0.1 0.1 1.1 -0.2 0.4 -0.3 -0.3 0.1 -0.3 0.1 -0.2 -0.7 0.3 -0.2 0.2 -0.1 0.2 -0.3 -0.2 -0.1 0.4 0.2 0.0 -0.2 1.0 0.2 -0.4 -0.2 -0.1 -0.2 -0.4 -0.4 -0.0 -0.1
Systolic blood pressure, automated reading 0.4 1.2 6.1 -0.7 -1.0 -0.8 -1.5 1.4 -1.1 -1.6 -0.5 -0.5 -1.2 -1.1 -1.1 -1.3 -0.9 -0.7 -0.6 -1.4 -0.9 0.8 -0.8 -0.8 -2.5 -0.9 -1.1 -1.4 -0.9 -1.0 -0.9 -0.8 -0.9 -0.4
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 1.6 -0.2 0.4 0.3 0.2 -1.3 0.0 -0.6 -0.2 -0.5 0.1 0.9 -0.5 0.8 0.2 0.1 -0.1 0.1 -0.6 0.1 -0.4 -0.2 -1.1 -0.4 0.0 0.3 0.4 0.3 -0.8 -0.2 -1.0 1.1
Angina 0.4 0.5 2.3 -0.0 -0.8 -0.7 -1.2 1.3 -0.4 -1.2 -0.0 0.4 0.1 -1.1 -0.6 -1.2 -0.6 -0.2 -0.6 -1.5 -0.2 0.5 -0.1 -0.2 -0.7 -0.5 -0.3 -1.0 -1.0 -0.6 -0.6 -0.6 0.4 0.0
Medication for hormone replacement therapy 0.8 0.9 1.9 -1.0 -0.4 -1.1 -0.7 0.9 -0.8 -0.3 -1.1 -1.4 -0.8 -1.2 -0.7 -1.0 -1.0 -1.2 -1.0 -1.1 -0.6 0.8 -0.8 -1.0 -0.9 -0.9 -1.3 -1.0 -0.8 -1.1 -0.7 -0.9 -0.6 -1.1
Vitamin and mineral supplements 8.8 11.9 16.6 4.1 2.9 3.5 3.0 -2.8 3.2 3.7 4.0 4.0 3.6 3.0 3.7 3.1 4.0 4.0 3.5 2.8 3.8 -2.9 4.0 4.0 2.4 3.5 3.4 3.5 3.5 3.9 2.2 3.9 3.0 3.2
Supplements: Zinc 0.2 0.2 1.6 0.3 0.6 0.2 0.7 0.3 0.5 0.7 0.4 0.3 0.4 -0.1 0.3 -0.1 0.5 0.4 0.6 0.1 0.3 -0.3 0.3 0.3 1.3 0.1 0.5 0.2 -0.2 0.1 1.1 0.4 0.6 -0.4
Medication: Co-codamol 1.1 1.3 3.7 -0.8 -1.9 -0.8 -1.9 1.0 -1.2 -1.9 -0.8 -0.5 -0.8 -1.2 -1.0 -1.1 -1.1 -0.8 -1.0 -1.3 -0.9 1.3 -0.9 -0.9 -1.0 -1.0 -0.9 -1.3 -1.6 -1.1 -0.4 -1.1 -0.8 -1.2
Medication: Metformin 2.4 3.4 5.9 1.9 1.2 2.3 1.3 -2.2 1.7 1.4 2.0 2.0 2.4 2.1 1.7 2.4 2.4 1.9 2.0 1.4 1.8 -1.3 1.8 1.9 0.6 1.5 1.8 2.1 1.9 2.2 0.2 1.9 1.2 2.4
Diabetes (father) 0.2 0.3 1.4 0.6 1.1 0.6 -0.2 -1.2 -0.3 -0.1 0.6 0.4 0.3 0.8 0.1 0.9 0.8 1.2 0.3 0.2 0.0 0.2 0.4 0.5 0.0 -0.1 -0.1 0.4 0.3 0.8 -0.3 -0.1 0.2 -0.3
Diabetes (mother) 0.4 0.6 1.4 1.0 0.2 1.1 0.7 -0.4 0.8 -0.8 1.1 0.9 0.5 0.5 0.4 0.4 1.0 1.2 1.1 0.8 0.4 -0.1 0.7 1.0 -0.0 0.6 0.6 0.6 0.5 0.8 0.4 1.1 0.5 1.1
Severe depression (siblings) 5.2 5.8 8.9 -2.6 -2.1 -2.6 -3.0 2.2 -2.6 -2.6 -2.6 -2.1 -2.4 -2.3 -2.5 -2.4 -2.3 -2.7 -2.6 -2.3 -2.4 2.3 -2.6 -2.6 -1.6 -2.2 -2.4 -2.7 -2.5 -2.8 -1.5 -2.4 -2.0 -2.2
Pack years adult smoking proportion 0.7 1.0 5.2 1.0 -0.1 0.9 -0.3 -0.9 0.6 -0.7 1.0 1.1 1.1 1.1 0.9 1.0 0.6 1.3 0.4 0.1 1.0 -0.8 1.0 1.0 -2.3 1.0 1.1 0.8 0.9 1.1 0.0 1.3 0.9 1.5
Impedance of leg (right) 5.2 25.2 36.2 -5.1 -2.7 -5.4 -4.6 5.0 -5.1 -3.3 -4.9 -4.9 -4.5 -5.7 -5.7 -5.6 -4.6 -5.0 -5.2 -5.7 -5.7 4.5 -5.3 -5.1 -2.6 -6.0 -5.7 -5.6 -5.7 -5.5 -3.7 -5.2 -4.5 -5.4
Leg fat-free mass (left) 9.7 51.4 69.9 7.2 5.3 8.2 6.7 -7.8 7.1 4.8 7.1 6.8 6.7 8.3 8.0 8.4 7.0 7.1 7.7 8.0 7.8 -6.2 7.4 7.3 3.2 8.1 7.6 8.3 8.1 8.0 4.8 7.2 5.5 7.5
Trunk fat percentage 0.1 0.6 2.3 0.4 -1.0 1.0 0.3 -0.7 0.6 0.2 0.6 1.0 0.4 1.1 0.8 0.9 0.5 0.4 0.6 0.5 1.0 -1.3 0.7 0.5 0.1 1.3 0.5 0.7 0.9 0.8 0.1 0.6 0.5 1.5
Hand grip strength (right) 20.3 55.3 69.4 8.2 7.5 8.2 7.9 -6.8 8.0 6.5 8.2 7.1 7.3 7.3 7.6 7.5 8.1 7.8 8.3 7.4 7.3 -6.5 7.9 8.2 3.9 6.8 8.0 8.3 7.8 8.3 4.6 8.0 6.2 6.8
Townsend deprivation index at recruitment 2.7 3.8 6.6 -2.3 -2.0 -1.8 -2.4 1.4 -2.6 -1.3 -2.3 -1.6 -1.4 -1.9 -1.8 -1.6 -2.3 -2.5 -2.2 -1.7 -1.8 1.6 -2.1 -2.2 -1.1 -1.8 -2.1 -2.1 -2.1 -2.1 -1.5 -1.7 -2.5 -1.3
Current tobacco smoking 0.9 1.5 4.5 -0.4 -1.1 -1.2 -0.7 1.8 -0.8 -2.1 -0.2 -0.9 -0.9 -2.0 -1.5 -1.9 -1.3 -0.2 -1.1 -1.4 -1.6 0.4 -0.8 -0.5 -1.3 -2.0 -1.3 -1.3 -1.3 -0.9 -1.1 -0.7 -0.7 -1.6
Average weekly fortified wine intake 5.4 6.3 9.2 -3.0 -2.4 -2.7 -1.9 2.1 -2.4 -2.8 -3.0 -2.9 -2.5 -2.4 -2.4 -2.3 -2.6 -2.8 -2.7 -2.2 -2.5 1.8 -2.8 -2.9 -1.2 -2.6 -2.9 -2.5 -1.7 -2.8 -2.4 -3.0 -1.9 -2.7
Maternal smoking around birth 0.5 0.7 3.5 -0.9 -0.9 -0.0 -1.9 0.2 -1.4 -1.1 -0.8 -1.1 -0.2 -0.2 -0.2 -0.2 -1.3 -1.0 -0.6 -0.5 -0.2 1.1 -0.7 -0.9 0.2 0.1 -0.9 -0.7 -0.2 -0.7 0.1 -0.9 -1.2 -0.2
Fed-up feelings 1.1 1.9 3.8 -1.4 -1.4 -1.6 -1.5 1.0 -1.2 -1.9 -1.5 -1.4 -1.8 -1.1 -1.6 -1.3 -1.9 -1.7 -1.7 -1.4 -1.4 0.8 -1.4 -1.5 -1.2 -1.0 -1.5 -1.5 -1.2 -1.4 -0.7 -1.3 -1.0 -0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 0.5 0.6 1.5 1.0 -0.8 0.8 -0.2 -0.7 0.4 -0.6 0.9 1.2 0.0 0.8 0.8 0.8 0.3 0.9 0.6 0.9 0.8 -0.9 1.0 0.8 -1.0 0.9 0.1 0.6 0.7 0.9 1.2 0.6 0.9 0.6
Relative age voice broke 0.4 0.7 5.3 -1.0 -2.3 -0.4 -1.0 0.0 -0.8 -0.5 -0.9 -0.9 -0.9 -0.0 -0.4 -0.1 -1.2 -1.0 -0.7 -0.5 -0.5 -0.2 -0.8 -1.0 -1.3 -0.2 -0.4 -0.5 -0.4 -0.7 0.1 -1.2 -0.9 -0.3
Taking other prescription medications 1.8 2.7 4.5 -1.8 -2.0 -1.6 -2.0 1.3 -1.7 -1.7 -1.7 -1.6 -1.9 -1.0 -2.0 -1.2 -1.8 -2.1 -1.8 -1.6 -1.9 1.7 -1.8 -1.8 0.6 -1.6 -1.4 -1.7 -1.4 -1.6 -1.4 -1.6 -1.6 -1.1
Age when periods started (menarche) 6.1 14.6 21.1 -4.0 -3.8 -4.4 -3.7 3.1 -4.1 -1.9 -4.0 -4.4 -3.7 -3.5 -4.5 -3.8 -4.2 -4.0 -4.3 -4.6 -4.6 2.8 -4.2 -4.0 -1.1 -4.3 -3.8 -4.3 -4.0 -4.0 -2.6 -4.1 -3.3 -3.3
Bilateral oophorectomy (both ovaries removed) 0.4 0.5 1.9 0.8 0.2 0.4 0.4 -0.2 0.5 0.3 0.7 0.5 0.3 0.4 0.9 0.4 0.7 0.6 0.4 0.7 0.9 -1.4 0.9 0.7 0.3 1.0 0.3 0.5 0.8 0.7 1.1 0.3 1.1 0.4
Heel bone mineral density (BMD) T-score, automated (left) 1.8 4.1 11.8 1.6 1.5 2.4 0.8 -3.4 1.1 1.0 1.5 1.3 2.0 3.2 2.2 3.1 1.7 1.9 1.6 2.0 2.1 -1.3 1.7 1.7 0.9 2.7 2.2 2.4 2.6 2.4 1.2 1.5 0.6 2.9
Tinnitus: Yes, but not now, but have in the past 0.4 0.4 1.4 0.6 -0.4 0.9 0.9 -0.6 0.6 -0.0 0.7 0.1 -0.2 0.7 0.7 0.7 0.5 0.6 0.6 0.9 0.5 -0.7 0.7 0.6 0.8 0.8 0.1 0.7 0.7 0.8 1.2 0.3 0.9 -0.0
Qualifications: CSEs or equivalent 0.8 1.0 2.3 -0.7 0.8 -1.1 -1.3 1.5 -0.9 -1.5 -0.8 -0.6 -1.3 -1.4 -1.1 -1.4 -0.6 -0.9 -1.0 -0.3 -1.2 0.9 -0.9 -0.8 -0.4 -1.2 -1.4 -1.2 -1.1 -1.0 0.2 -0.6 -0.7 -1.0
Serious illness, injury or assault to yourself 1.2 1.5 3.7 -0.5 -1.9 -1.2 -1.6 1.9 -0.8 -0.3 -0.4 0.0 -0.7 -1.5 -1.2 -1.4 -1.1 -0.5 -1.0 -1.9 -0.7 0.8 -0.6 -0.7 -1.9 -1.2 -1.1 -1.4 -1.9 -1.1 -1.7 -0.9 0.3 -1.0
High blood pressure 2.6 7.1 16.4 -2.6 -4.0 -2.8 -2.4 3.1 -2.2 -2.7 -2.4 -2.4 -3.3 -2.9 -3.1 -3.2 -2.6 -2.4 -2.8 -3.1 -2.9 1.8 -2.7 -2.6 -2.0 -2.7 -2.2 -3.0 -2.5 -2.9 -1.5 -2.6 -1.7 -2.1
Hayfever, allergic rhinitis or eczema 0.7 1.6 5.0 1.6 2.2 1.6 1.0 -0.8 1.2 0.4 1.6 1.5 0.9 0.7 1.1 0.9 1.3 1.1 1.6 1.8 1.2 0.2 1.3 1.4 2.2 1.0 1.4 1.2 0.9 1.3 0.7 1.0 0.2 1.1
Multivitamins +/- minerals 13.4 17.1 22.4 -4.7 -3.3 -4.5 -3.8 3.5 -3.9 -3.2 -4.7 -4.4 -4.2 -3.8 -4.4 -3.8 -4.5 -4.7 -4.3 -3.8 -4.4 3.8 -4.6 -4.6 -4.1 -4.3 -4.2 -4.2 -4.1 -4.6 -3.3 -4.5 -3.1 -4.2
Stomach or abdominal pain in last month 1.9 2.4 5.2 -1.4 -0.7 -1.8 -1.8 2.3 -1.5 -1.7 -1.4 -1.8 -1.2 -1.7 -1.6 -2.0 -2.0 -1.9 -1.7 -1.6 -1.8 0.3 -1.5 -1.4 -1.1 -1.6 -1.0 -1.9 -1.3 -1.7 0.2 -1.2 -1.1 -1.3
Supplements: Glucosamine 3.3 4.3 9.1 -2.4 -2.5 -1.8 -2.6 1.1 -2.1 -3.0 -2.4 -2.5 -2.1 -1.2 -2.1 -1.3 -2.3 -2.6 -2.0 -1.5 -2.2 2.3 -2.4 -2.4 -1.1 -1.8 -2.0 -1.9 -1.8 -2.1 -1.5 -2.4 -2.0 -1.6
Diverticular disease/diverticulitis (self-reported) 2.5 2.9 6.9 -2.1 -0.4 -1.6 -2.1 0.8 -2.3 -1.6 -2.2 -2.2 -2.1 -0.7 -1.5 -0.9 -2.4 -2.1 -2.0 -1.3 -1.7 1.3 -2.0 -2.2 -0.1 -1.1 -1.3 -1.7 -1.0 -1.7 0.5 -2.6 -2.6 -1.0
Medication: Atenolol 2.6 3.2 6.9 -1.5 -1.3 -2.0 -1.4 2.3 -1.7 -2.6 -1.5 -1.2 -1.9 -2.3 -1.9 -2.4 -1.9 -1.3 -2.1 -1.9 -1.9 1.5 -1.7 -1.6 -0.8 -1.9 -1.8 -2.1 -1.7 -1.9 -0.9 -1.8 -1.2 -1.9
Medication: Levothyroxine sodium 2.2 3.8 8.5 -2.6 -1.4 -2.0 -1.5 1.1 -1.5 0.2 -2.7 -2.5 -1.6 -1.3 -2.0 -1.2 -1.8 -2.6 -2.0 -1.6 -2.0 2.9 -2.5 -2.5 0.3 -1.8 -2.2 -1.7 -2.1 -2.2 -2.1 -1.9 -2.0 -1.8
Sitting height 11.9 84.7 108.2 9.8 8.6 10.1 9.2 -9.4 9.6 6.4 9.4 9.2 8.6 9.9 9.9 10.1 9.4 9.5 9.9 10.1 9.5 -7.7 9.7 9.7 5.0 9.4 9.6 10.4 9.9 10.3 6.2 9.4 7.5 9.1
Chronic bronchitis/emphysema (father) 0.1 0.1 1.1 0.3 0.0 -0.4 0.2 0.5 0.5 0.1 0.2 0.6 0.4 -0.3 -0.1 -0.4 0.5 -0.1 0.1 -0.3 0.0 -0.7 0.2 0.3 1.1 -0.0 0.0 -0.1 0.1 0.0 0.2 0.5 0.7 0.4
High blood pressure (mother) 1.9 2.7 6.6 -1.9 -0.4 -1.5 -1.7 1.2 -1.9 -2.6 -1.9 -1.4 -1.9 -1.3 -1.7 -1.4 -1.9 -1.8 -2.2 -1.2 -1.8 1.2 -1.9 -1.9 -1.2 -1.3 -1.6 -1.6 -1.3 -1.7 -0.8 -1.6 -2.3 -0.9
Body mass index (BMI) 1.0 4.4 8.8 1.8 -0.4 2.6 1.8 -1.9 2.0 1.1 1.9 1.9 1.6 2.5 2.4 2.3 1.7 1.7 2.1 2.1 2.5 -2.6 2.1 1.9 1.0 3.0 2.1 2.2 2.6 2.2 1.9 2.2 1.5 3.0
Impedance of leg (left) 4.5 21.8 31.1 -4.7 -2.5 -5.1 -4.5 4.8 -4.8 -3.4 -4.5 -4.3 -4.1 -5.3 -5.3 -5.2 -4.3 -4.5 -4.9 -5.3 -5.2 4.2 -4.9 -4.7 -2.8 -5.6 -5.2 -5.2 -5.2 -5.1 -3.4 -4.9 -4.1 -5.1
Leg predicted mass (left) 9.7 51.5 69.4 7.2 5.3 8.2 6.7 -7.7 7.2 4.8 7.1 6.8 6.8 8.3 8.0 8.3 7.0 7.1 7.7 8.0 7.8 -6.2 7.5 7.3 3.2 8.1 7.6 8.3 8.1 8.0 4.9 7.2 5.5 7.5
Trunk fat mass 1.9 8.0 13.2 2.7 1.1 3.4 2.4 -3.0 2.8 1.6 2.8 3.1 2.7 3.4 3.2 3.3 2.7 2.6 3.0 2.8 3.3 -2.9 3.0 2.8 1.1 3.5 2.8 3.2 3.2 3.2 1.4 2.9 2.1 3.6
Waist circumference 1.6 6.0 9.9 2.3 1.0 3.1 2.1 -2.6 2.5 1.4 2.5 2.5 2.4 2.8 2.8 2.8 2.0 2.3 2.8 2.3 2.9 -2.3 2.6 2.4 1.0 3.1 2.5 2.7 2.7 2.7 1.6 2.5 1.9 3.0
Number of incorrect matches in round 8.4 13.9 20.8 -3.7 -3.6 -4.5 -4.2 4.0 -4.1 -2.4 -3.8 -3.3 -3.3 -4.3 -4.2 -4.6 -3.4 -3.5 -4.1 -4.2 -4.2 2.6 -3.9 -3.6 -2.5 -4.0 -3.5 -4.4 -4.0 -4.2 -2.3 -3.1 -2.7 -3.5
Past tobacco smoking 2.8 5.2 7.5 2.7 2.0 2.7 1.3 -2.6 1.8 1.0 2.7 2.5 2.0 2.4 2.4 2.6 2.7 2.7 2.4 2.0 2.5 -1.7 2.6 2.6 0.5 2.3 2.5 2.3 2.3 2.7 0.5 2.4 1.9 2.7
Alcohol usually taken with meals 1.9 3.1 6.3 -1.8 -0.7 -1.6 -1.7 1.6 -1.9 -0.4 -1.7 -1.5 -1.3 -2.1 -1.7 -1.9 -1.8 -1.8 -1.4 -1.8 -1.6 2.5 -1.8 -1.8 -1.3 -1.9 -2.0 -1.9 -2.3 -2.0 -1.1 -1.8 -1.8 -2.4
Nervous feelings 3.8 7.0 11.7 -2.5 -1.6 -3.1 -3.0 2.2 -2.6 -2.7 -2.6 -2.6 -2.8 -2.7 -2.9 -2.7 -2.6 -2.4 -2.9 -2.7 -2.9 2.2 -2.6 -2.6 -1.2 -3.0 -3.2 -3.1 -3.1 -2.8 -2.3 -2.5 -0.7 -3.4
Frequency of tenseness / restlessness in last 2 weeks 2.5 3.8 5.9 -1.8 -2.0 -2.4 -2.0 2.4 -1.6 -2.0 -1.8 -1.3 -2.0 -2.1 -2.2 -2.3 -2.4 -2.1 -2.2 -2.4 -2.1 1.2 -1.9 -1.9 -0.1 -2.0 -2.2 -2.3 -2.2 -2.1 -1.3 -1.8 -0.6 -1.8
Hearing difficulty/problems with background noise 16.5 26.3 35.3 5.3 4.5 5.7 4.3 -5.7 4.9 2.8 5.3 5.5 5.5 5.8 5.3 5.8 5.5 5.2 5.7 5.1 5.1 -4.8 5.2 5.4 2.0 5.2 5.4 5.6 5.2 5.7 2.7 5.9 4.5 5.8
Hair/balding pattern: Pattern 2 1.2 1.5 4.6 1.2 0.7 1.0 1.6 -1.7 1.5 2.1 1.2 0.9 1.6 1.2 0.8 1.3 0.9 1.5 1.0 0.6 0.7 -0.9 1.1 1.2 2.0 0.4 1.5 1.2 0.8 1.4 0.2 1.3 1.4 0.8
Had menopause 0.4 0.5 1.6 -0.3 -0.2 -0.7 -0.8 1.2 -0.3 -0.2 -0.2 0.8 -0.2 -1.3 -0.6 -1.1 0.4 -0.3 -0.3 -0.8 -0.3 0.5 -0.3 -0.3 -0.5 -0.8 -0.9 -0.8 -1.1 -0.7 -1.3 -0.4 0.6 -1.1
Had other major operations 0.1 0.2 1.4 0.3 0.1 -0.3 0.1 -0.2 0.4 -0.0 0.2 0.2 0.5 -0.2 0.2 -0.1 0.9 0.5 -0.1 -0.4 0.2 -0.0 0.4 0.3 0.2 -0.2 0.1 0.1 0.3 0.2 -0.9 0.2 1.2 -0.3
Forced vital capacity (FVC) 0.3 1.1 5.1 1.0 0.9 0.3 2.2 -0.4 1.9 1.3 0.7 0.4 1.4 0.4 0.9 0.5 0.9 0.7 0.7 0.4 0.7 -0.9 1.0 0.9 1.8 0.5 1.3 1.1 0.5 0.8 0.6 0.9 1.7 0.0
Heel bone mineral density (BMD) T-score, automated (right) 2.8 6.3 10.5 2.4 2.2 2.7 1.7 -3.1 2.0 1.1 2.2 2.0 2.6 3.0 2.9 2.9 2.7 2.5 2.4 2.6 2.8 -2.0 2.5 2.5 1.6 3.2 3.0 2.8 2.9 2.8 2.4 2.4 1.4 3.1
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 2.2 -0.9 -0.9 -0.6 -0.4 0.6 -0.4 0.4 -0.9 -1.2 -0.5 -0.3 -0.7 -0.5 -1.5 -0.9 -0.7 -0.8 -0.7 0.4 -0.8 -0.9 -0.1 -0.3 -0.8 -0.7 -0.3 -0.8 0.4 -0.6 -0.6 -0.3
Qualifications: None of the above 1.6 3.5 11.0 -1.3 -3.3 -2.0 -2.2 2.6 -2.0 -1.9 -1.2 -1.4 -1.5 -2.2 -2.0 -2.6 -1.4 -1.5 -1.9 -2.9 -1.9 0.6 -1.4 -1.4 -0.7 -1.6 -2.0 -2.4 -1.9 -1.9 0.2 -1.4 -0.3 -2.0
Financial difficulties in last 2 years 0.1 0.1 2.1 -0.2 0.3 -0.5 0.1 0.1 -0.0 0.7 -0.2 0.1 0.3 -0.3 -0.2 -0.2 -0.0 -0.4 0.0 -0.6 -0.0 0.4 -0.1 -0.2 -0.1 -0.3 -0.2 -0.1 0.2 -0.2 -1.5 -0.0 0.2 -0.0
Mouth/teeth dental problems 1.7 2.6 8.0 1.2 2.0 1.3 2.8 -2.5 2.0 0.8 1.0 1.1 0.6 2.2 1.3 2.1 1.2 1.5 1.3 2.4 1.0 -2.0 1.2 1.3 0.7 1.2 1.9 2.0 1.9 1.7 0.9 1.2 1.3 1.3
Heart attack 0.9 1.1 4.7 -1.0 -2.2 -1.2 -1.5 0.7 -1.1 -1.3 -1.0 -0.9 -0.9 -0.7 -1.0 -1.1 -0.9 -1.2 -1.5 -1.6 -0.9 0.5 -1.0 -1.0 -0.6 -0.4 0.1 -1.1 -1.0 -1.1 0.5 -0.9 -0.5 -0.5
Allergy 1.0 2.2 4.1 -1.6 -1.8 -1.8 -1.1 1.5 -1.5 -0.6 -1.6 -1.4 -1.4 -1.4 -1.7 -1.6 -1.5 -1.2 -1.7 -2.0 -1.8 0.4 -1.6 -1.6 -1.8 -1.7 -1.6 -1.6 -1.3 -1.6 -0.9 -1.3 -1.0 -1.4
Pain all over the body in last month 1.2 1.3 2.8 1.3 1.4 1.1 0.9 -1.7 1.4 0.9 1.2 1.6 0.9 1.1 1.0 1.3 1.1 1.1 1.4 1.3 0.9 -0.2 1.1 1.3 -0.2 0.5 1.0 1.3 1.1 1.3 -0.2 1.5 1.5 0.8
Diabetes (self-reported) 1.6 2.5 4.6 1.9 1.7 1.8 1.2 -1.4 1.5 1.1 2.0 1.9 1.6 1.6 1.3 1.6 2.1 2.0 1.8 1.2 1.5 -1.1 1.7 1.8 1.4 1.2 1.8 1.6 1.8 1.8 -0.0 1.3 1.1 2.1
Hayfever/allergic rhinitis (self-reported) 0.8 1.0 2.5 1.1 0.3 1.1 1.0 -1.2 0.9 1.2 1.0 0.3 0.4 1.3 1.0 1.2 0.8 1.1 0.8 1.6 0.6 -0.6 1.0 1.1 1.4 0.8 0.7 1.3 1.0 1.1 1.3 0.8 1.2 -0.5
Medication: Ramipril 2.8 3.6 7.8 -2.0 -1.6 -2.3 -1.6 2.2 -1.6 -1.7 -1.9 -1.8 -1.6 -2.3 -2.1 -2.4 -2.2 -2.1 -2.1 -2.8 -1.8 0.8 -1.9 -2.1 -1.0 -1.8 -1.1 -2.3 -2.0 -2.2 -1.4 -2.0 -1.1 -1.2
Medication: Simvastatin 1.9 2.7 6.9 -2.0 -2.6 -1.6 -1.1 1.0 -1.4 -1.3 -2.0 -1.2 -1.1 -1.2 -1.6 -1.1 -1.9 -2.1 -1.9 -2.2 -1.4 1.8 -1.8 -2.0 -1.1 -1.4 -1.5 -1.6 -1.6 -1.7 -2.3 -2.0 -1.2 -0.9
Fluid intelligence score 1.1 2.3 7.5 1.1 1.7 1.7 2.0 -2.1 1.6 2.7 1.1 0.7 1.1 2.0 1.5 2.1 1.6 1.1 1.6 1.6 1.2 -1.4 1.2 1.1 1.0 1.3 1.2 1.9 1.9 1.7 0.6 0.8 0.8 1.2
Illnesses of siblings 0.1 0.2 2.0 -0.1 0.7 0.0 0.5 -0.2 0.0 1.4 -0.2 -0.2 -0.3 0.2 0.2 0.3 -0.2 -0.0 0.2 0.4 0.1 0.5 -0.0 -0.1 -0.2 0.0 0.0 0.2 0.4 0.0 0.4 -0.1 -0.7 0.3
Neuroticism score 5.5 11.6 17.0 -3.3 -2.6 -3.8 -3.7 3.3 -3.4 -3.4 -3.2 -2.8 -3.5 -3.5 -3.9 -3.8 -3.8 -3.5 -3.8 -4.1 -3.8 2.5 -3.5 -3.4 -3.1 -3.5 -3.6 -4.0 -3.6 -3.6 -2.4 -3.1 -2.0 -2.9
Weight 5.9 29.1 39.9 5.4 3.6 6.3 5.1 -5.6 5.4 3.7 5.3 5.3 5.2 6.2 6.1 6.2 5.1 5.2 5.9 5.8 6.0 -4.8 5.6 5.4 2.5 6.3 5.6 6.1 6.1 6.0 3.7 5.4 4.1 5.9
Impedance of arm (right) 4.1 19.2 26.5 -4.6 -2.7 -5.2 -4.4 4.0 -4.3 -3.5 -4.7 -4.0 -4.6 -4.5 -5.0 -4.5 -4.0 -4.5 -5.0 -4.7 -4.8 4.0 -4.7 -4.6 -2.5 -4.8 -4.8 -4.9 -4.9 -4.8 -3.5 -4.4 -3.4 -4.3
Arm fat percentage (right) 0.1 0.6 3.4 0.1 -1.5 0.8 0.2 -0.6 0.5 -0.2 0.2 0.6 -0.0 1.1 0.7 0.8 0.2 0.1 0.3 0.5 0.9 -1.4 0.4 0.2 0.3 1.5 0.4 0.5 0.8 0.5 0.6 0.6 0.2 1.8
Trunk fat-free mass 10.2 58.3 78.7 7.9 6.8 8.9 7.2 -8.2 7.6 5.4 7.7 7.2 7.5 8.5 8.4 8.8 7.4 7.7 8.5 8.5 8.2 -5.8 7.9 7.9 3.8 8.3 8.0 8.8 8.4 8.6 5.1 7.6 5.4 7.8
Hip circumference 2.2 9.7 15.1 2.7 1.6 3.8 2.9 -3.5 3.1 2.4 2.7 2.8 2.8 3.9 3.5 3.9 2.6 2.7 3.4 3.7 3.5 -2.9 3.0 2.8 1.9 3.9 3.1 3.6 3.6 3.4 2.0 3.1 1.7 3.9
Time employed in main current job 0.3 0.4 1.3 -0.6 -0.6 -0.3 -0.6 0.4 -0.4 -1.1 -0.5 -0.1 -0.8 -0.3 -0.8 -0.4 -0.7 -0.7 -0.3 -0.7 -0.6 0.5 -0.6 -0.7 0.8 -0.2 -0.6 -0.7 -0.9 -0.6 -0.9 -0.7 -0.2 -0.1
Alcohol intake versus 10 years previously 0.2 0.2 1.7 0.5 1.1 0.1 0.1 0.2 0.3 0.4 0.5 0.5 0.3 -0.1 0.3 -0.2 0.7 0.4 0.2 0.3 0.1 -0.7 0.5 0.7 -0.1 0.2 0.2 0.3 0.2 0.4 1.3 0.9 0.7 -0.1
Father’s age at death 0.3 0.3 2.0 -0.4 0.3 -0.6 -0.1 0.5 -0.5 -0.8 -0.3 -0.6 -0.3 -0.8 -0.7 -0.7 -0.3 -0.6 -0.2 -0.3 -0.7 0.6 -0.5 -0.3 -0.3 -1.0 -0.5 -0.6 -0.6 -0.5 -1.4 -0.1 -0.5 -0.5
Worrier / anxious feelings 2.9 5.4 11.4 -2.1 -2.4 -2.7 -2.8 2.2 -2.3 -2.2 -2.1 -1.5 -2.3 -2.4 -2.6 -2.6 -2.9 -2.4 -2.7 -3.4 -2.3 1.6 -2.2 -2.2 -2.5 -2.2 -2.2 -2.8 -2.3 -2.4 -2.1 -2.0 -0.9 -1.4
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.1 2.9 1.1 0.0 0.9 0.4 -1.2 1.1 -0.0 1.0 0.9 -0.1 1.5 0.8 1.1 1.0 1.1 0.9 1.1 0.6 -1.2 0.9 1.0 -0.0 1.1 0.9 1.1 1.7 1.2 1.6 1.1 0.9 1.5
Falls in the last year 4.3 5.9 9.1 2.9 2.0 2.5 2.5 -2.0 2.8 1.7 2.9 2.6 2.3 2.2 2.5 2.2 2.7 3.0 2.7 2.4 2.4 -2.1 2.8 2.8 1.1 2.1 2.5 2.6 2.3 2.6 1.1 2.5 3.0 2.1
Hair/balding pattern: Pattern 3 2.1 3.1 8.1 -1.9 -2.8 -1.4 -2.8 0.9 -2.3 -2.8 -1.8 -1.6 -2.2 -0.9 -1.8 -1.1 -1.6 -2.0 -1.9 -1.6 -1.8 1.3 -1.9 -1.9 -1.1 -1.2 -1.3 -1.7 -1.6 -1.7 -0.8 -1.8 -2.1 -0.8
Number of live births 2.4 3.4 5.8 -2.2 -2.1 -1.6 -2.1 1.2 -1.8 -1.1 -2.1 -2.4 -1.4 -1.5 -2.0 -1.6 -1.8 -2.2 -2.0 -2.0 -2.3 1.1 -2.2 -2.1 -1.4 -2.0 -2.1 -1.7 -1.6 -1.9 -0.6 -1.9 -1.8 -1.8
Forced expiratory volume in 1-second (FEV1) 2.0 6.8 13.5 2.3 2.3 2.2 3.7 -2.4 3.3 2.2 2.0 1.8 2.2 2.6 2.7 2.5 2.8 2.1 2.4 2.8 2.5 -2.9 2.5 2.4 2.9 2.8 3.2 3.0 2.6 2.5 2.1 2.7 2.7 2.2
Pulse rate 0.4 0.7 3.7 0.2 0.4 0.2 1.5 -1.1 1.3 1.6 0.0 0.3 0.6 0.9 0.4 0.7 0.2 -0.2 0.7 0.9 0.0 -1.9 0.3 0.2 1.3 0.3 0.7 0.9 1.1 0.5 0.9 0.4 0.5 0.4
Happiness 0.1 0.2 0.5 -0.2 -0.2 0.4 -0.5 -0.6 -0.6 -0.3 -0.2 -0.3 -0.3 0.7 0.2 0.7 -0.5 -0.4 -0.0 0.5 0.1 0.2 -0.1 -0.3 -0.1 0.5 -0.6 0.1 0.5 0.1 0.2 -0.7 -0.6 0.1
Noisy workplace 0.4 0.5 2.4 -0.1 -1.1 -0.7 -1.0 0.8 -0.8 -1.3 -0.1 0.3 -0.1 -0.9 -0.7 -0.8 -0.1 -0.3 -0.6 -0.9 -0.7 -0.2 -0.3 -0.1 -1.5 -1.0 -0.6 -0.7 -0.8 -0.4 -0.8 0.2 0.1 -0.6
Qualifications: A levels/AS levels or equivalent 1.2 2.8 11.2 1.7 3.3 1.3 1.6 -1.7 1.7 1.2 1.5 1.6 1.6 1.6 1.7 1.7 1.3 1.9 1.6 2.2 1.8 -0.9 1.6 1.6 1.1 1.5 2.3 1.8 1.5 1.7 0.5 1.2 1.0 1.6
Serious illness, injury or assault of a close relative in last 2 years 0.8 0.9 3.5 -1.2 -0.1 -0.7 -0.9 0.5 -0.9 -0.4 -1.2 -1.1 -0.3 -0.8 -0.6 -0.7 -0.9 -1.2 -0.8 -1.1 -0.4 1.9 -1.0 -1.3 -0.4 -0.5 -0.7 -0.9 -1.3 -1.1 -0.7 -1.7 -1.0 -0.9
Mouth/teeth dental problems: Dentures 0.2 0.3 3.5 0.1 -1.9 0.1 -1.2 0.6 -0.4 0.1 0.2 0.2 0.4 -0.4 0.1 -0.3 0.1 -0.1 0.1 -0.9 0.3 -0.1 0.2 0.1 -0.5 0.2 -0.6 -0.4 -0.0 -0.1 -0.0 0.7 0.4 0.3
Asthma 0.2 0.4 2.6 -0.7 -1.0 -0.2 -0.3 0.1 -0.2 0.0 -0.8 -0.9 -0.6 0.1 -0.2 -0.0 -0.4 -0.8 -0.6 0.0 -0.1 0.8 -0.6 -0.7 -0.9 0.3 0.0 -0.2 -0.3 -0.5 1.6 -0.8 -0.8 -0.3
Medication: Ibuprofen (e.g. Nurofen) 1.7 2.1 4.3 -1.3 -1.3 -1.6 -1.3 1.6 -1.4 -0.7 -1.1 -1.5 -1.1 -2.1 -1.6 -2.0 -1.1 -1.0 -1.5 -1.5 -1.5 1.7 -1.4 -1.2 -0.1 -1.8 -1.8 -1.6 -1.7 -1.5 -1.3 -1.3 -1.2 -1.8
Medication: Cholesterol lowering 1.6 2.5 8.7 -1.6 -3.0 -1.6 -1.5 1.7 -1.6 -1.6 -1.4 -1.4 -0.7 -1.6 -1.6 -1.6 -1.3 -1.6 -1.8 -2.6 -1.3 1.1 -1.4 -1.5 -1.8 -1.5 -1.2 -1.7 -1.5 -1.6 -1.5 -1.5 -1.0 -1.0
Depression (self-reported) 2.1 2.5 5.2 -1.5 0.2 -1.6 -2.2 1.6 -1.8 -2.3 -1.5 -1.5 -1.4 -1.5 -1.7 -1.4 -1.2 -1.5 -1.4 -1.8 -1.6 1.9 -1.6 -1.6 -1.0 -1.8 -1.6 -1.7 -1.6 -1.7 -1.2 -1.6 -1.8 -1.0
Medication: Lansoprazole 0.4 0.4 4.5 0.1 -0.4 -0.5 -0.2 0.1 0.2 0.8 0.2 0.4 0.9 -0.6 -0.4 -0.5 0.5 -0.2 -0.0 -1.4 -0.2 0.2 0.1 0.1 -0.6 -0.8 -0.3 -0.4 -0.3 -0.1 -2.1 0.2 1.2 -0.5
Prospective memory result 0.5 0.7 4.4 -1.0 -2.1 -0.4 -1.1 -0.0 -1.0 -0.8 -0.9 -0.4 -1.3 -0.3 -0.5 -0.4 -0.8 -0.9 -0.8 -0.4 -0.5 0.3 -0.8 -0.9 -1.1 -0.3 -1.0 -0.7 -0.7 -0.7 -0.4 -0.6 -0.4 -0.4
Lung cancer (father) 0.5 0.6 1.5 0.8 -0.6 0.4 0.4 -0.4 0.8 0.4 0.7 1.2 0.2 0.7 0.6 0.3 0.9 0.9 0.7 0.3 0.7 -1.1 0.7 0.7 -0.8 1.1 0.8 0.5 0.9 0.6 0.9 0.8 1.1 1.2
Illnesses of mother 1.1 1.4 2.4 1.4 0.6 1.1 1.2 -1.1 1.3 1.6 1.4 1.1 1.5 1.1 1.1 1.2 1.1 1.4 1.1 0.7 1.1 -1.1 1.3 1.4 0.8 0.7 1.5 1.4 1.2 1.4 0.8 1.2 1.1 1.2
Forced expiratory volume in 1-second (FEV1), Best measure 1.0 3.1 6.6 1.5 1.2 1.2 2.6 -1.6 2.3 1.7 1.3 1.2 1.7 1.8 1.8 1.6 1.9 1.5 1.4 1.5 1.6 -2.1 1.7 1.6 2.0 1.9 2.4 2.0 1.5 1.6 1.9 2.1 2.2 1.2
Pulse wave Arterial Stiffness index 1.2 1.4 7.3 -1.4 -2.7 -0.5 -1.6 -1.2 -1.6 0.5 -1.3 -1.2 -1.6 0.6 -1.2 0.5 -1.2 -1.5 -1.1 -0.7 -1.2 0.5 -1.3 -1.3 -1.1 -0.6 -0.9 -0.6 -0.5 -0.6 -1.6 -1.3 -1.4 -0.2
Impedance of arm (left) 3.1 14.3 20.2 -3.9 -1.8 -4.5 -3.8 3.6 -3.7 -2.9 -4.0 -3.3 -4.0 -4.0 -4.2 -4.0 -3.6 -3.8 -4.2 -3.9 -4.1 3.5 -4.0 -4.0 -1.6 -4.2 -4.1 -4.2 -4.3 -4.2 -3.0 -3.9 -2.8 -4.0
Arm fat mass (right) 2.3 9.4 17.0 2.8 1.2 3.7 2.6 -3.1 3.0 1.8 2.9 3.0 2.7 3.6 3.5 3.5 2.7 2.7 3.2 3.2 3.6 -3.1 3.1 2.9 1.6 4.0 3.1 3.4 3.6 3.3 2.3 3.2 2.1 4.1
Trunk predicted mass 10.4 59.6 80.1 8.0 6.8 8.9 7.3 -8.2 7.7 5.5 7.8 7.3 7.6 8.6 8.5 8.8 7.5 7.8 8.6 8.6 8.3 -5.9 8.0 8.0 3.9 8.4 8.1 8.9 8.4 8.7 5.3 7.7 5.5 7.8
Standing height 6.4 63.6 84.3 8.4 9.0 9.0 7.5 -8.8 8.0 6.0 8.2 8.0 8.2 8.6 8.7 9.2 8.1 8.2 8.8 8.8 8.4 -5.6 8.4 8.4 3.8 8.0 8.0 9.2 8.3 9.0 4.3 7.8 6.0 7.1
Length of working week for main job 0.2 0.3 2.1 0.0 -0.2 -0.2 0.9 0.4 0.5 0.8 0.1 -0.5 -0.6 -0.4 -0.3 -0.5 -0.2 0.1 -0.1 -0.1 -0.4 -0.3 -0.1 -0.1 1.4 -0.2 -0.1 -0.2 -0.8 -0.1 0.8 -0.4 0.3 -0.8
Exposure to tobacco smoke at home 0.3 0.4 2.6 -0.8 -0.3 -0.0 -0.4 -0.0 -0.9 0.7 -0.8 -0.2 0.2 -0.2 -0.0 -0.0 -0.5 -0.9 -0.4 -0.8 0.1 0.3 -0.5 -0.8 -1.6 0.3 -0.4 -0.5 -0.5 -0.5 -1.0 -0.5 -0.9 0.2
Breastfed as a baby 6.0 7.5 11.5 -2.6 -1.5 -2.9 -2.3 3.1 -2.5 -2.1 -2.5 -2.6 -2.3 -3.3 -2.9 -3.1 -2.8 -2.8 -2.9 -2.8 -2.7 3.1 -2.7 -2.8 -0.7 -3.1 -2.8 -3.1 -3.2 -3.0 -2.4 -3.1 -1.9 -3.4
Tense / ‘highly strung’ 10.6 17.5 23.2 -4.5 -2.7 -4.2 -4.5 3.7 -4.5 -3.9 -4.4 -4.0 -4.0 -4.1 -4.4 -3.9 -4.7 -4.4 -4.5 -4.0 -4.3 4.1 -4.5 -4.6 -2.2 -4.4 -4.8 -4.5 -4.6 -4.5 -3.6 -4.4 -3.6 -4.2
Seen doctor (GP) for nerves, anxiety, tension or depression 6.6 10.1 13.8 -3.3 -2.0 -3.5 -3.7 2.6 -3.4 -3.5 -3.3 -3.0 -3.1 -2.8 -3.5 -2.9 -3.6 -3.3 -3.6 -3.5 -3.5 2.8 -3.4 -3.4 -1.8 -3.2 -3.2 -3.6 -3.3 -3.3 -2.5 -3.5 -2.4 -2.8
Hair/balding pattern: Pattern 4 0.4 0.9 2.4 0.7 1.6 0.4 1.2 -0.5 0.9 1.3 0.6 0.7 1.4 0.5 1.2 0.6 0.7 0.7 0.9 0.6 1.5 -1.0 1.1 0.7 0.5 1.4 0.7 0.7 0.7 0.6 -0.2 1.1 1.3 1.0
Birth weight of first child 3.8 6.9 9.9 2.9 2.0 2.9 2.4 -2.6 2.5 2.9 3.0 3.1 3.0 2.5 2.9 2.8 2.6 2.6 3.0 2.3 3.1 -1.9 3.0 2.9 1.1 2.6 2.3 2.9 2.6 2.9 0.2 2.7 2.8 2.4
Peak expiratory flow (PEF) 17.9 41.5 68.7 6.4 5.8 6.3 7.9 -5.2 7.5 5.1 6.3 6.3 4.1 5.9 6.8 5.8 7.0 6.2 6.9 8.3 6.7 -6.7 6.6 6.5 5.8 7.1 7.0 6.9 6.7 6.5 4.4 7.0 6.4 5.9
Pulse wave reflection index 5.7 7.0 11.4 -3.1 -3.0 -2.4 -2.9 1.1 -3.4 -1.1 -3.0 -2.7 -2.6 -1.9 -2.6 -1.7 -2.6 -3.0 -2.9 -2.7 -2.3 3.0 -2.9 -3.0 -2.9 -2.3 -2.5 -2.6 -2.7 -2.6 -3.2 -2.7 -3.0 -1.7
Ever highly irritable/argumentative for 2 days 0.7 0.8 3.7 -0.7 -1.9 -1.0 -0.5 1.1 -0.3 0.6 -0.6 -1.0 -0.5 -0.9 -0.9 -1.1 -1.2 -0.8 -0.9 -1.6 -0.9 -0.4 -0.6 -0.6 -1.5 -0.8 -1.1 -0.9 -0.6 -0.8 -0.3 -0.3 0.6 -0.8
Loud music exposure frequency 1.0 1.1 2.6 1.0 -0.2 1.0 1.2 -1.4 1.0 1.2 1.0 0.8 0.9 1.6 0.8 1.5 1.1 1.1 1.0 1.1 0.6 -1.0 0.9 1.1 0.3 0.7 1.3 1.4 1.2 1.3 0.8 1.0 1.0 0.6
Qualifications: O levels/GCSEs or equivalent 3.8 6.0 20.8 2.6 4.6 2.3 2.4 -2.1 2.4 2.0 2.4 2.3 2.3 2.0 2.9 2.3 2.0 3.0 2.5 3.1 2.9 -1.4 2.6 2.5 1.8 2.5 2.7 2.6 2.4 2.5 1.6 1.8 1.5 1.9
Mouth/teeth dental problems: Bleeding gums 0.7 0.9 3.1 -0.8 -0.7 -0.8 -0.8 1.7 -1.0 -0.1 -0.7 -0.6 -0.4 -1.3 -0.9 -1.2 -0.4 -1.1 -0.6 -1.2 -0.8 1.8 -0.9 -0.8 -0.7 -0.8 -1.0 -1.0 -1.1 -1.0 -0.1 -0.9 -1.5 -0.6
Blood clot in the leg (DVT) 1.6 2.1 7.2 1.4 1.5 1.4 0.8 -1.5 1.2 0.8 1.4 1.0 1.9 1.2 1.8 1.5 1.3 1.4 1.7 1.6 1.9 -1.1 1.6 1.5 2.7 1.6 0.9 1.4 1.2 1.4 0.2 1.6 1.7 0.8
Medication: Paracetamol 3.1 5.1 9.7 -2.2 -1.7 -2.7 -2.6 2.8 -2.2 -1.0 -2.1 -2.2 -2.1 -2.7 -2.4 -2.8 -2.4 -2.0 -2.5 -3.1 -2.2 1.3 -2.2 -2.2 -1.4 -2.4 -2.2 -2.7 -2.4 -2.5 -1.7 -2.3 -1.3 -2.3
Headache pain in last month 3.0 5.1 7.9 -2.1 -2.1 -2.6 -2.4 2.2 -2.2 -1.0 -2.0 -2.4 -1.9 -2.5 -2.6 -2.5 -2.1 -2.0 -2.5 -2.8 -2.5 2.5 -2.3 -2.1 -0.7 -2.6 -2.5 -2.5 -2.5 -2.3 -1.9 -2.2 -1.6 -2.4
Medication for cholesterol, blood pressure or diabetes 1.8 3.0 11.8 1.7 3.4 1.8 1.7 -1.7 1.7 1.6 1.6 1.2 1.3 1.5 1.8 1.7 1.8 1.7 2.0 2.7 1.6 -0.7 1.6 1.8 1.9 1.6 1.1 1.9 1.5 1.7 1.9 1.6 1.1 0.5
Glaucoma (self-reported) 1.0 1.1 4.1 -1.1 -0.2 -1.3 -1.5 1.6 -1.1 -2.0 -1.1 -0.6 -1.1 -1.0 -1.1 -1.5 -0.8 -1.1 -1.4 -1.3 -1.0 0.0 -1.1 -1.1 -0.4 -0.5 -0.6 -1.3 -0.9 -1.3 0.4 -0.9 -0.5 -0.7
Gout (self-reported) 2.3 3.1 6.2 2.4 0.6 1.8 1.9 -1.4 1.8 1.5 2.5 2.5 2.3 1.3 1.5 1.5 2.2 2.4 1.6 0.6 1.6 -1.4 2.2 2.4 0.1 1.2 1.7 1.7 1.0 2.1 0.3 2.0 2.2 1.3
Hypothyroidism/myxoedema (self-reported) 0.8 1.7 4.2 -1.5 -1.4 -1.4 -0.7 0.8 -0.7 0.1 -1.5 -1.4 -0.7 -1.1 -1.6 -1.0 -1.0 -1.5 -1.1 -1.3 -1.5 2.0 -1.6 -1.4 0.6 -1.6 -1.3 -1.1 -1.6 -1.4 -2.1 -0.9 -1.1 -1.2
Medication: Amlodipine 1.2 1.7 4.6 -1.4 -1.5 -1.2 -0.7 1.2 -0.9 -1.0 -1.3 -1.1 -0.8 -1.4 -1.3 -1.2 -1.2 -1.6 -1.1 -1.5 -1.1 1.6 -1.3 -1.4 -1.5 -1.4 -1.1 -1.2 -1.4 -1.4 -2.1 -1.4 -1.2 -0.7
Medication: Ventolin 100micrograms inhaler 0.2 0.3 1.4 -0.4 -0.9 -0.5 0.2 1.2 0.0 -0.6 -0.3 -0.2 -0.4 -0.9 -0.3 -0.8 -0.3 -0.6 -0.4 -0.3 -0.2 0.5 -0.3 -0.4 0.2 -0.5 -0.5 -0.5 -0.4 -0.6 -0.7 -0.4 0.4 -0.5
Birth weight 9.6 20.8 32.0 4.8 5.7 4.9 4.6 -5.0 4.5 4.0 4.6 4.9 4.8 4.9 4.9 5.3 5.0 4.2 4.9 4.8 4.9 -3.1 4.8 4.8 2.3 4.4 4.0 5.2 4.7 5.1 1.6 4.5 3.5 4.3
Chronic bronchitis/emphysema (mother) 0.3 0.3 1.9 0.3 -0.1 0.4 -0.5 0.2 -0.0 -0.4 0.3 0.3 0.3 0.4 0.8 0.1 0.3 0.1 0.4 0.8 1.0 -0.1 0.5 0.3 1.1 1.4 0.3 0.1 0.5 0.1 1.3 0.4 0.8 0.4
High blood pressure (siblings) 0.3 0.4 6.7 -0.3 -1.5 -0.1 -1.0 0.2 -0.5 -2.6 -0.3 -0.2 -0.6 0.1 -0.5 -0.3 0.1 -0.5 -0.4 -0.4 -0.6 -0.5 -0.5 -0.4 0.2 0.1 -0.2 -0.5 -0.1 -0.3 0.7 -0.2 -0.1 0.2
Forced vital capacity (FVC), Best measure 0.1 0.3 1.8 0.2 0.1 -0.3 1.4 -0.1 1.0 0.9 -0.0 -0.2 0.9 0.1 0.2 0.1 0.1 0.1 -0.0 -0.4 0.1 -0.5 0.3 0.2 1.1 -0.0 0.8 0.4 -0.3 0.1 0.3 0.3 1.2 -0.6
Body fat percentage 0.1 0.4 2.0 0.1 -1.4 0.8 0.1 -0.4 0.3 -0.1 0.2 0.7 0.2 0.8 0.6 0.7 0.2 0.1 0.3 0.2 0.7 -1.2 0.4 0.2 0.0 1.1 0.2 0.4 0.6 0.5 0.2 0.4 0.2 1.4
Leg fat percentage (right) 0.2 0.6 5.8 -1.0 -2.4 -0.3 -0.6 0.6 -0.6 -0.9 -0.8 -0.6 -0.7 -0.4 -0.6 -0.5 -0.9 -1.0 -0.8 -0.9 -0.5 -0.2 -0.7 -0.9 -0.3 -0.2 -0.9 -0.7 -0.5 -0.7 -0.4 -0.6 -0.6 0.1
Arm fat-free mass (right) 11.1 57.0 77.1 7.9 6.4 8.8 7.2 -7.8 7.6 5.7 7.8 7.2 7.7 8.2 8.3 8.4 7.5 7.7 8.5 8.2 8.1 -6.0 7.9 7.9 3.6 8.0 7.8 8.6 8.3 8.5 5.1 7.6 5.7 7.4
Exposure to tobacco smoke outside home 0.5 0.6 2.1 -1.0 -0.7 -0.7 -0.6 0.5 -1.0 0.1 -0.9 -1.1 -0.1 -0.6 -0.5 -0.5 -1.1 -1.1 -0.9 -0.9 -0.5 0.7 -0.7 -0.9 -1.0 -0.7 -1.0 -0.7 -0.4 -0.7 -1.4 -0.7 -0.7 -0.3
Comparative body size at age 10 9.6 26.5 35.4 5.4 3.3 5.3 5.8 -4.2 6.0 2.7 5.4 5.4 4.0 5.1 5.2 4.7 5.5 5.4 5.5 5.2 5.1 -6.0 5.4 5.4 4.5 5.5 5.7 5.4 5.3 5.4 4.1 5.6 5.5 5.0
Number of full brothers 0.3 0.3 2.3 0.5 0.9 0.1 0.3 -0.5 0.9 -0.4 0.4 0.5 0.4 0.4 0.3 0.4 1.0 0.4 0.2 0.6 0.2 -0.2 0.4 0.6 -0.1 0.3 0.1 0.5 0.2 0.5 0.3 1.2 1.5 0.3
Worry too long after embarrassment 0.2 0.4 1.2 -0.2 1.0 -0.5 -0.6 0.5 -0.6 -0.1 -0.1 0.3 0.3 -1.0 -0.4 -0.9 -0.3 0.0 -0.4 -1.1 -0.2 0.9 -0.2 -0.2 -1.1 -0.5 -0.4 -0.7 -0.8 -0.5 -0.9 -0.3 -0.1 -0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 10.5 13.6 19.0 -3.8 -3.0 -3.8 -4.4 3.6 -4.0 -3.7 -3.9 -3.9 -3.6 -3.6 -3.7 -3.8 -4.2 -4.1 -3.9 -3.7 -3.5 4.1 -3.8 -3.9 -1.4 -3.2 -3.9 -4.2 -4.0 -4.1 -1.5 -3.7 -3.4 -3.2
Wheeze or whistling in the chest in last year 0.2 0.4 3.4 0.4 -1.9 0.3 0.0 -0.0 0.7 0.3 0.4 0.5 0.6 0.2 0.5 0.2 0.4 0.2 0.2 0.5 0.4 -0.9 0.4 0.5 -1.7 0.3 0.3 0.5 0.4 0.3 1.0 0.6 1.3 -0.3
Number of children fathered 4.7 5.3 10.2 -2.7 -2.4 -2.7 -1.4 1.9 -1.7 -1.7 -2.7 -2.4 -1.5 -2.3 -2.5 -2.2 -2.3 -3.0 -2.8 -2.8 -2.6 2.1 -2.5 -2.5 -1.3 -2.8 -2.4 -2.1 -2.5 -2.5 -1.5 -2.0 -0.9 -3.2
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.4 3.9 -0.1 -2.0 -0.4 0.0 0.3 0.2 1.0 -0.0 0.1 -0.7 -0.2 -0.3 -0.5 0.2 -0.2 -0.0 -0.7 -0.4 -0.8 -0.1 -0.1 -1.8 -0.2 -0.0 -0.3 -0.2 -0.2 0.5 -0.0 1.0 -0.1
Age at first live birth 0.2 0.4 2.9 0.4 0.5 0.3 1.5 -0.4 0.9 1.7 0.5 0.3 0.2 0.2 0.3 0.2 0.3 0.3 0.7 0.6 0.4 -0.0 0.4 0.5 0.9 0.2 1.3 0.6 0.3 0.4 0.2 0.4 -0.2 0.5
Pulse wave peak to peak time 2.2 2.6 11.3 2.0 3.4 1.1 2.1 0.5 2.1 -0.1 1.9 1.7 2.2 0.0 1.8 0.2 1.8 2.0 1.6 1.3 1.8 -0.8 1.9 1.9 1.4 1.1 1.4 1.3 1.0 1.2 1.8 1.8 1.9 0.6
Health satisfaction 0.6 0.7 4.1 -0.2 -2.0 -1.1 -0.1 1.7 -0.3 -1.8 -0.1 0.1 -0.5 -1.0 -0.8 -1.4 -0.6 -0.2 -0.8 -1.3 -0.6 -0.6 -0.2 -0.3 0.4 -0.5 -0.7 -1.1 -0.5 -0.7 -0.4 -0.5 1.1 -0.6
Shortness of breath walking on level ground 0.2 0.3 1.8 0.2 -1.3 0.2 0.5 0.1 0.3 0.1 0.3 -0.1 0.7 0.3 0.5 0.1 0.4 0.1 0.2 -0.2 0.6 -0.2 0.5 0.4 -0.5 0.6 0.3 0.2 0.3 0.1 0.9 0.3 1.3 -0.5
Qualifications: College or University degree 0.5 1.4 6.0 0.7 1.4 1.1 1.7 -2.4 1.2 1.0 0.6 0.9 0.7 1.6 0.9 2.0 0.7 0.6 0.9 1.7 0.8 -0.8 0.7 0.8 0.7 0.5 1.7 1.7 1.1 1.3 -0.7 1.1 -0.3 1.6
Eye problems/disorders: None of the above 1.7 1.9 4.3 1.5 1.9 1.2 1.5 -0.3 1.8 1.4 1.4 1.3 2.1 0.6 1.6 0.6 1.4 1.4 1.6 0.8 1.6 -0.7 1.5 1.4 1.3 1.4 1.3 1.3 1.3 1.1 1.7 1.7 1.6 0.9
Mouth/teeth dental problems: Loose teeth 0.1 0.1 0.9 0.2 -0.2 0.0 -0.6 0.2 -0.3 -1.0 0.3 0.3 -0.6 -0.2 -0.2 -0.3 -0.3 0.1 -0.0 -0.3 -0.1 -0.1 0.1 0.0 0.6 0.2 0.1 -0.4 -0.1 0.0 -0.5 -0.2 -0.2 0.4
Emphysema/chronic bronchitis 0.2 0.3 2.3 0.6 -0.0 0.4 0.4 0.1 0.8 0.4 0.6 0.6 0.7 0.0 0.5 0.1 0.7 0.4 0.6 0.0 0.5 0.4 0.6 0.6 -0.6 0.2 -0.0 0.4 -0.0 0.3 -0.1 0.7 1.5 -0.1
Medication for pain relief, constipation, heartburn 6.7 11.4 19.2 3.2 3.1 4.3 3.5 -3.8 3.4 1.7 3.2 3.0 2.7 4.0 3.7 3.8 3.6 3.0 3.9 4.4 3.2 -2.7 3.2 3.3 1.7 3.8 3.5 4.0 3.4 3.6 3.6 3.5 1.9 3.1
Neck or shoulder pain in last month 1.4 1.9 6.5 1.4 -0.0 1.2 1.5 -0.6 1.6 1.5 1.4 1.0 0.4 1.6 1.1 1.0 0.9 1.5 1.3 1.3 1.0 -2.6 1.3 1.3 -0.1 1.6 1.9 1.3 1.7 1.4 2.2 1.1 1.4 1.6
Medication: Blood pressure 2.0 3.6 10.3 -1.9 -3.2 -2.1 -1.9 1.9 -1.9 -2.1 -1.9 -1.2 -2.0 -1.6 -2.0 -1.9 -2.4 -2.0 -2.2 -2.5 -1.7 1.0 -1.9 -2.0 -1.8 -1.4 -1.2 -2.1 -1.7 -1.9 -1.4 -2.0 -1.4 -0.4
Angina (self-reported) 0.7 0.9 3.6 -0.3 -1.2 -1.0 -1.3 1.8 -0.6 -1.3 -0.2 0.2 -0.3 -1.4 -1.0 -1.6 -0.9 -0.5 -0.9 -1.9 -0.6 0.6 -0.4 -0.5 -0.7 -0.7 -0.6 -1.4 -1.3 -0.9 -0.6 -0.8 0.4 -0.3
Migraine (self-reported) 0.3 0.4 2.2 -0.3 -0.2 -0.8 -0.1 1.0 -0.2 1.1 -0.3 -0.4 -0.8 -0.7 -0.8 -1.0 0.1 -0.2 -0.6 -0.7 -0.8 -0.1 -0.5 -0.2 1.5 -0.5 -0.1 -0.6 0.1 -0.4 0.5 -0.2 -0.4 -0.1
Medication: Ibuprofen 2.1 2.5 4.8 -1.4 -1.5 -1.8 -1.4 1.8 -1.6 -0.9 -1.3 -1.7 -1.6 -2.2 -1.7 -2.1 -1.6 -1.1 -1.7 -1.5 -1.6 1.9 -1.5 -1.4 -0.5 -1.9 -1.9 -1.8 -1.6 -1.6 -1.3 -1.5 -1.1 -2.0
Medication: Allopurinol 0.8 1.1 2.7 1.6 0.4 1.0 1.2 -0.8 1.2 1.5 1.6 1.4 1.5 0.7 0.7 0.8 0.7 1.6 0.9 -0.0 0.8 -0.6 1.3 1.4 -0.1 0.5 0.8 0.9 0.5 1.3 -0.0 0.9 1.3 0.7
Medication: Omeprazole 0.2 0.3 1.2 0.2 0.8 0.3 0.1 -0.9 0.2 0.6 -0.1 0.2 0.2 0.9 0.6 0.9 0.4 0.0 0.1 0.5 0.9 0.1 0.4 0.0 1.1 1.1 0.2 0.4 0.2 0.3 0.2 -0.1 0.1 0.6
Medication: Seretide 50 evohaler 0.2 0.2 1.2 -0.3 -1.1 -0.1 0.1 -0.3 -0.2 0.7 -0.3 -0.6 0.1 0.1 0.1 0.4 -0.2 -0.8 -0.1 0.1 0.1 0.7 -0.2 -0.2 0.3 -0.3 -0.6 0.1 -0.3 -0.1 -0.1 -0.5 -0.0 -0.9
Mean time to correctly identify matches 11.5 21.9 39.8 -4.9 -3.5 -4.7 -5.8 4.4 -5.2 -4.1 -4.9 -4.3 -3.7 -4.6 -4.7 -4.4 -4.6 -4.7 -4.5 -4.3 -4.4 6.3 -5.0 -5.0 -2.6 -4.5 -5.2 -5.1 -5.2 -5.2 -3.8 -4.9 -4.7 -4.6
Heart disease (mother) 1.1 1.3 2.9 -1.4 -0.9 -1.1 -0.8 0.9 -1.0 -1.7 -1.4 -1.1 -1.1 -1.1 -1.1 -1.0 -1.2 -1.4 -1.3 -0.8 -1.0 0.8 -1.3 -1.4 0.1 -1.0 -1.3 -1.2 -1.4 -1.3 -1.2 -1.3 -0.6 -1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 2.3 -0.9 -0.1 -0.6 -0.3 0.9 -0.3 -0.0 -0.9 -0.7 -0.3 -1.0 -1.1 -0.9 -0.5 -1.0 -0.4 -1.1 -1.2 1.0 -1.1 -0.8 0.1 -1.5 -0.8 -0.7 -1.0 -1.0 -0.5 -0.5 -1.2 -0.4
Whole body fat mass 2.1 8.7 14.9 2.8 1.0 3.6 2.6 -3.0 2.9 1.8 2.9 3.1 2.8 3.5 3.3 3.4 2.7 2.7 3.1 3.0 3.4 -3.1 3.1 2.9 1.2 3.7 2.9 3.3 3.4 3.3 1.8 3.1 2.2 3.9
Leg fat mass (right) 1.6 6.3 10.9 2.2 0.3 3.2 2.3 -2.7 2.5 1.6 2.4 2.4 2.3 3.1 2.9 3.0 2.2 2.2 2.6 2.5 2.9 -2.7 2.5 2.4 0.9 3.2 2.4 2.9 3.0 2.8 1.5 2.6 1.9 3.3
Arm predicted mass (right) 10.9 55.9 75.0 7.8 6.3 8.7 7.2 -7.6 7.5 5.6 7.8 7.2 7.6 8.0 8.3 8.3 7.4 7.7 8.4 8.1 8.1 -6.1 7.9 7.8 3.5 8.0 7.8 8.5 8.2 8.4 5.0 7.5 5.6 7.4
Pulse rate, automated reading 3.8 12.4 17.5 3.5 3.4 3.8 4.2 -3.6 3.9 3.2 3.5 3.5 3.6 3.3 3.6 3.7 3.5 3.5 4.0 3.8 3.5 -3.7 3.6 3.6 1.9 3.1 3.6 4.0 3.6 3.9 1.6 3.9 2.9 3.6
Alcohol intake frequency. 0.5 1.1 3.3 1.1 0.6 0.9 0.1 -1.0 0.8 0.1 1.0 0.7 0.5 1.2 1.1 1.0 0.9 1.5 0.8 1.1 1.0 -0.9 1.1 1.0 0.9 1.3 0.7 0.9 1.3 1.1 1.8 1.1 1.6 1.2
Comparative height size at age 10 11.2 61.6 78.1 8.6 8.8 8.7 7.3 -8.1 7.8 5.8 8.3 8.3 8.1 8.2 8.6 8.7 7.7 8.2 8.7 8.7 8.4 -5.8 8.5 8.4 4.9 7.8 7.7 8.7 8.1 8.8 4.7 7.4 6.4 6.6
Number of full sisters 0.4 0.5 3.8 0.6 0.6 -0.3 0.4 0.8 0.4 -2.0 0.6 0.3 0.5 -0.6 -0.0 -0.8 0.7 0.7 -0.2 -0.2 -0.0 -0.9 0.5 0.7 1.3 -0.0 0.3 -0.1 -0.2 0.1 0.2 1.0 1.2 -0.4
Suffer from ‘nerves’ 0.6 0.9 3.2 -0.4 -0.3 -0.9 -1.3 1.4 -0.9 -1.7 -0.3 -0.5 -0.7 -1.3 -0.5 -1.3 -1.0 -0.5 -0.8 -1.0 -0.5 -0.2 -0.3 -0.5 -1.0 -0.7 -1.3 -1.2 -0.9 -0.9 -0.0 -0.4 1.1 -1.8
Overall health rating 0.3 0.7 3.3 -0.4 -1.7 -0.9 -1.7 1.0 -0.7 -1.8 -0.4 -0.0 -0.4 -0.7 -0.8 -0.9 -0.9 -0.5 -1.1 -1.3 -0.7 0.5 -0.5 -0.5 0.1 -0.5 -1.0 -1.0 -0.8 -0.6 0.0 -0.2 0.4 -0.3
Chest pain or discomfort 0.4 0.6 2.1 1.1 -0.6 0.8 -0.2 -0.6 0.7 -0.3 1.2 1.0 0.2 0.6 0.6 0.5 0.2 1.2 0.6 1.0 0.5 -0.9 0.9 1.1 -0.4 0.5 1.1 0.7 0.9 0.9 1.4 0.9 0.8 0.6
Had major operations 0.8 0.9 3.0 -0.5 -0.1 -1.1 -0.8 1.0 -0.9 0.1 -0.5 -0.9 -0.7 -1.3 -0.8 -1.1 -1.6 -0.7 -0.9 -1.1 -0.5 1.0 -0.4 -0.7 1.1 -0.8 -1.4 -1.2 -1.2 -0.8 -1.7 -1.1 0.2 -1.3
Age at last live birth 0.4 0.5 3.7 0.5 0.8 0.6 1.1 -0.8 1.0 1.2 0.5 -0.0 0.5 0.6 0.3 0.4 -0.1 0.2 0.7 0.7 0.1 0.1 0.3 0.4 1.9 0.3 1.4 0.7 0.5 0.6 1.1 0.2 -0.4 0.6
Family relationship satisfaction 0.3 0.4 4.6 -0.0 -1.1 0.3 -0.3 -0.9 -0.3 -0.4 -0.0 -0.2 -0.9 1.0 -0.0 0.7 0.2 -0.2 -0.1 1.1 -0.1 -0.6 -0.0 -0.0 2.1 0.7 0.3 0.2 0.6 0.3 0.3 -0.1 -0.1 0.5
Leg pain on walking 0.4 0.5 1.8 0.7 -1.2 0.1 -0.2 -0.2 0.5 -1.1 0.6 0.6 0.1 0.6 0.4 0.2 0.3 0.1 -0.0 0.0 0.6 -0.9 0.7 0.6 0.7 1.3 0.9 0.2 0.4 0.5 1.2 0.9 1.3 0.8
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.5 1.8 0.6 -0.4 0.6 0.1 0.8 0.3 0.9 0.8 0.7 0.6 -0.3 0.7 -0.3 1.1 0.7 0.9 0.3 0.7 -0.2 0.7 0.7 -1.3 0.6 0.0 0.1 0.4 0.2 1.1 0.9 0.8 0.0
Commuting to job workplace: Car/motor vehicle 0.4 0.4 4.1 0.2 -0.4 0.1 1.4 -0.8 1.0 2.0 0.2 0.3 0.6 0.9 0.2 0.7 0.7 -0.0 0.3 -0.4 0.2 -0.7 0.3 0.3 0.3 0.4 0.2 0.7 0.3 0.6 -0.3 0.2 1.0 0.5
Illness, injury, bereavement, stress in last 2 years 0.2 0.3 1.8 0.1 0.3 0.2 0.6 -0.2 0.3 -0.9 0.0 -0.1 -0.6 0.5 0.2 0.4 0.1 0.3 -0.0 0.9 0.0 -1.2 0.1 0.1 1.4 0.3 0.4 0.3 0.6 0.3 0.9 0.0 -0.3 0.5
Medication: Aspirin 3.6 4.7 8.6 -2.0 -2.4 -2.9 -1.9 2.5 -1.9 -1.8 -2.0 -1.4 -1.7 -2.6 -2.5 -2.6 -2.2 -1.9 -2.4 -2.9 -2.1 1.8 -2.0 -2.1 -1.6 -2.4 -1.8 -2.6 -2.1 -2.4 -2.8 -2.1 -0.9 -1.6
Supplements: Vitamin C 0.9 1.0 2.3 -1.1 -1.5 -0.9 -0.5 0.8 -0.9 -1.2 -1.0 -1.4 -1.3 -0.7 -1.2 -1.0 -1.4 -0.8 -0.9 -0.7 -1.4 -0.7 -1.1 -1.1 0.5 -1.0 -0.5 -1.0 -1.0 -1.1 -0.3 -1.2 -0.7 -1.0
Knee pain experienced in last month 1.3 2.0 11.1 -1.4 -3.3 -1.4 -1.2 1.3 -1.1 -1.6 -1.4 -1.4 -1.9 -1.1 -1.6 -1.5 -1.4 -1.6 -1.7 -1.2 -1.6 0.0 -1.4 -1.4 -0.8 -0.9 -1.0 -1.6 -1.3 -1.4 -0.3 -1.0 -0.3 -1.1
Hypertension (Self-reported) 2.2 6.1 16.2 -2.3 -4.0 -2.5 -2.1 2.8 -2.0 -2.5 -2.1 -2.1 -3.1 -2.8 -2.9 -3.0 -2.5 -2.1 -2.6 -3.0 -2.6 1.7 -2.4 -2.4 -1.9 -2.4 -2.0 -2.8 -2.3 -2.6 -1.3 -2.5 -1.5 -2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.0 1.2 2.0 -1.1 -0.2 -1.3 -1.0 0.6 -1.1 -0.9 -1.2 -1.3 -0.7 -1.0 -1.1 -0.7 -1.3 -1.3 -1.2 -1.1 -1.1 1.3 -1.1 -1.1 0.3 -1.4 -1.4 -1.1 -1.0 -1.1 -1.4 -1.1 -1.0 -1.1
Illnesses of father: Heart disease 4.2 5.9 9.0 -2.7 -1.9 -2.3 -2.7 2.3 -2.5 -1.5 -2.6 -2.7 -2.8 -2.4 -2.3 -2.3 -2.8 -2.6 -2.5 -2.0 -2.1 2.4 -2.5 -2.7 -1.0 -2.2 -2.9 -2.5 -3.0 -2.7 -1.7 -2.5 -2.0 -2.7
Illnesses of siblings: Diabetes 1.9 2.3 4.6 1.8 1.6 1.4 1.3 -1.1 2.1 1.8 1.8 2.1 1.9 1.2 1.4 1.3 1.7 2.0 1.5 1.0 1.6 -1.3 1.7 1.7 0.7 1.2 1.6 1.6 0.9 1.6 -0.4 1.6 2.1 0.9
Smoking status: Previous 1.8 2.7 5.1 -2.0 -1.5 -1.8 -1.1 2.0 -1.2 -0.8 -2.1 -1.7 -1.6 -1.5 -1.6 -1.8 -1.8 -2.3 -1.5 -1.3 -1.6 1.9 -1.9 -2.0 -0.2 -1.1 -1.7 -1.7 -1.5 -2.1 0.3 -1.9 -1.3 -1.9
Forced expiratory volume in 1-second (FEV1), predicted 1.9 4.0 8.8 2.0 2.4 2.7 1.3 -2.9 1.6 2.0 2.0 1.3 2.1 2.8 2.0 3.0 1.9 2.1 2.3 2.3 1.7 -1.1 1.8 2.0 1.3 1.8 1.8 2.5 2.1 2.4 1.4 1.7 0.9 1.2
Whole body fat-free mass 10.7 61.1 81.5 8.0 6.4 9.0 7.3 -8.4 7.7 5.5 7.8 7.3 7.6 8.9 8.7 9.0 7.6 7.8 8.6 8.7 8.4 -6.4 8.1 8.0 3.7 8.6 8.2 9.0 8.7 8.8 5.3 7.8 5.8 8.0
Leg fat-free mass (right) 10.6 56.8 75.7 7.6 5.7 8.5 6.9 -8.0 7.5 5.0 7.5 7.2 7.1 8.7 8.4 8.7 7.3 7.6 8.1 8.4 8.2 -6.4 7.8 7.7 3.2 8.5 8.1 8.7 8.5 8.4 5.2 7.6 5.9 7.8
Arm fat percentage (left) 0.2 0.9 3.6 0.4 -1.2 1.0 0.5 -0.7 0.8 0.2 0.5 0.9 0.2 1.2 1.0 0.9 0.4 0.5 0.6 0.8 1.2 -1.6 0.8 0.5 0.6 1.7 0.7 0.8 1.1 0.8 0.9 0.9 0.5 1.9
Average weekly red wine intake 2.0 2.9 6.2 -1.8 -2.0 -2.0 -1.4 1.5 -1.5 -0.4 -1.8 -1.3 -1.7 -1.5 -1.9 -1.6 -2.1 -1.7 -1.7 -2.1 -1.6 1.4 -1.8 -2.0 -0.7 -1.6 -1.5 -2.0 -1.8 -1.9 -2.5 -2.1 -0.6 -1.3
Handedness (chirality/laterality): Left-handed 1.6 2.0 7.0 -1.8 -1.4 -1.7 -0.5 0.9 -1.1 -1.4 -1.9 -1.9 -2.6 -0.8 -1.6 -1.3 -1.2 -1.8 -1.6 -0.5 -1.7 0.5 -1.8 -1.8 0.7 -0.9 -1.4 -1.4 -1.0 -1.6 -0.6 -1.7 -1.0 -0.9
Mood swings 9.8 17.7 24.4 -4.5 -3.9 -4.4 -4.6 3.8 -4.5 -4.4 -4.5 -4.0 -4.9 -3.7 -4.8 -4.1 -4.7 -4.9 -4.8 -4.2 -4.7 3.1 -4.6 -4.5 -2.5 -3.9 -4.4 -4.7 -4.0 -4.5 -2.5 -4.0 -3.5 -3.0
Loneliness, isolation 1.1 1.5 7.0 -1.2 -1.5 -1.1 -1.8 1.0 -1.3 -2.6 -1.1 -1.1 -1.5 -0.8 -1.3 -1.2 -1.5 -1.5 -1.4 -1.1 -1.3 0.6 -1.2 -1.2 -0.7 -0.7 -1.0 -1.3 -0.9 -1.2 0.3 -1.0 -0.9 -0.7
Long-standing illness, disability or infirmity 1.5 2.4 6.5 -1.4 -1.8 -1.9 -1.7 1.5 -1.0 -0.6 -1.5 -1.3 -0.5 -1.4 -2.0 -1.4 -1.9 -1.6 -1.6 -2.5 -1.8 1.5 -1.6 -1.5 -0.7 -1.9 -1.2 -1.6 -1.9 -1.5 -1.6 -1.2 -1.3 -0.6
Ever had bowel cancer screening 0.2 0.2 1.6 0.5 0.8 0.1 -0.4 0.1 0.1 -0.3 0.5 0.5 1.2 -0.1 0.2 -0.1 -0.1 0.2 0.2 -0.8 0.5 0.5 0.5 0.4 -0.0 0.1 0.3 -0.0 -0.2 0.1 -0.3 0.2 0.6 -0.1
Diabetes diagnosed by doctor 2.6 4.3 7.9 2.4 1.9 2.3 1.8 -2.0 2.0 2.0 2.4 2.3 2.2 2.1 1.8 2.3 2.5 2.4 2.3 1.8 2.1 -1.4 2.2 2.3 1.0 1.7 2.1 2.1 2.2 2.4 0.1 1.9 1.4 2.8
Ever had stillbirth, spontaneous miscarriage or termination 2.0 2.1 4.5 -1.2 -1.2 -1.5 -0.1 1.7 -1.0 -0.8 -1.0 -1.7 -1.5 -1.9 -1.8 -1.9 -1.8 -1.1 -1.5 -1.4 -1.9 1.6 -1.4 -1.2 0.2 -2.1 -1.4 -1.5 -1.4 -1.4 -0.9 -1.5 -1.6 -1.9
Friendships satisfaction 0.4 0.5 1.9 0.4 -0.6 0.3 -0.2 -1.0 -0.0 -0.7 0.3 0.3 -0.4 1.3 0.6 0.9 0.7 0.4 0.2 1.1 0.7 -0.7 0.5 0.3 0.3 1.4 0.3 0.4 1.0 0.5 0.1 0.3 1.0 0.7
Qualifications: nursing, teaching 0.3 0.4 4.5 -0.6 0.9 -0.5 0.3 -0.0 -0.0 0.8 -0.8 -0.7 -0.4 -0.5 -0.3 -0.2 0.0 -0.7 -0.3 0.4 -0.2 2.1 -0.6 -0.5 0.6 -0.6 0.1 -0.1 -0.7 -0.6 -1.0 -0.5 -1.1 -0.4
Commuting to job workplace: Walk 0.5 0.6 3.7 0.1 1.9 1.0 -0.5 -1.5 -0.4 -0.7 0.2 0.7 0.1 0.9 0.5 1.3 0.3 0.4 0.4 1.2 0.4 -0.2 0.2 0.2 -0.2 0.3 0.1 0.6 0.8 0.6 -1.0 0.4 -0.8 1.0
Eye problems/disorders: Cataract 0.8 1.0 4.7 -0.8 -1.4 -0.5 -1.2 -0.5 -1.3 -1.5 -0.8 -0.8 -1.5 -0.1 -0.8 0.1 -1.3 -1.0 -0.9 0.2 -0.8 0.5 -0.8 -0.8 -1.1 -0.8 -0.8 -0.6 -1.1 -0.5 -2.2 -1.1 -0.9 -0.6
Mouth/teeth dental problems: Mouth ulcers 0.7 1.1 3.3 -0.7 -0.8 -0.9 -1.2 1.8 -1.1 -0.2 -0.7 -0.6 -0.3 -1.5 -0.8 -1.4 -1.1 -0.8 -0.8 -1.7 -0.7 1.1 -0.7 -0.9 0.3 -1.0 -1.3 -1.3 -1.2 -1.2 -0.3 -1.2 -0.6 -1.5
Medication for cholesterol 1.6 2.4 7.0 1.8 2.6 1.5 1.1 -1.2 1.3 0.9 1.8 2.0 1.8 1.0 1.5 1.2 1.8 1.6 1.7 1.8 1.4 -0.9 1.6 1.9 1.7 1.1 1.8 1.5 1.1 1.6 0.7 2.1 0.8 1.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.3 1.9 -0.0 0.5 0.3 -0.4 -0.3 -0.3 1.1 -0.0 0.2 0.7 0.2 0.3 0.5 -0.6 -0.4 0.6 0.1 0.5 0.8 0.1 -0.2 1.2 0.2 -0.5 -0.0 0.0 0.1 -1.4 -0.5 -0.2 0.3
Back pain experienced in last month 2.1 3.1 8.1 1.7 0.7 1.1 2.0 -0.8 2.1 1.6 1.6 1.1 1.0 1.5 1.6 1.0 1.7 1.7 1.6 1.6 1.5 -2.9 1.7 1.7 2.8 2.0 2.0 1.6 2.0 1.6 2.0 2.0 2.3 1.7
Mineral and other dietary supplements 7.7 10.4 14.5 3.4 3.3 3.4 2.6 -3.2 2.8 2.6 3.4 3.3 3.0 3.4 3.5 3.4 3.1 3.5 3.1 2.8 3.6 -3.5 3.5 3.4 0.9 3.6 3.3 3.3 3.8 3.6 1.9 3.5 2.7 3.8
Breast cancer (self-reported) 0.5 0.5 2.5 0.6 1.0 0.3 0.9 0.7 0.9 1.6 0.6 0.7 1.2 -0.6 0.8 -0.2 1.3 0.6 0.6 0.3 1.0 -0.1 0.8 0.7 0.4 0.2 0.1 0.5 -0.4 0.1 0.7 0.9 0.9 -0.7
Asthma (self-reported) 0.2 0.3 2.4 -0.5 -0.9 -0.1 -0.2 0.1 -0.2 -0.1 -0.6 -0.7 -0.4 0.1 -0.1 -0.0 -0.3 -0.6 -0.5 0.1 -0.1 0.8 -0.5 -0.5 -1.2 0.3 0.0 -0.1 -0.2 -0.4 1.5 -0.8 -0.7 -0.3
Osteoporosis (self-reported) 0.3 0.3 2.7 0.3 0.9 -0.1 -0.3 -0.3 -0.2 -0.1 0.2 0.3 0.2 -0.3 -0.6 0.2 0.3 0.2 -0.2 0.0 -0.6 0.7 -0.1 0.2 0.9 -1.2 -0.7 -0.1 -1.0 0.2 -1.6 -0.2 -0.5 -0.6
Osteoarthritis (self-reported) 4.3 5.5 16.3 -2.8 -4.0 -2.5 -1.9 1.4 -2.0 -2.2 -3.0 -3.2 -3.1 -1.4 -2.5 -1.7 -2.6 -2.7 -2.6 -1.9 -2.7 2.0 -2.8 -2.8 -1.0 -2.0 -1.9 -2.2 -1.6 -2.4 -0.4 -2.6 -2.0 -1.5
Medication: Aspirin 4.2 5.5 9.5 -2.3 -2.7 -3.1 -2.2 2.8 -2.0 -2.3 -2.3 -1.6 -2.1 -2.8 -2.6 -2.9 -2.5 -2.3 -2.7 -2.9 -2.2 1.7 -2.2 -2.4 -1.2 -2.3 -1.9 -2.8 -2.4 -2.6 -2.3 -2.3 -1.0 -1.7
Medication: Gliclazide 0.2 0.2 1.0 -0.4 -0.9 -0.2 -0.1 -0.4 -0.3 0.1 -0.4 -0.4 0.1 0.5 -0.5 0.4 0.4 -0.2 -0.5 -0.5 -0.5 -1.0 -0.4 -0.3 0.3 -0.2 -0.0 0.0 0.1 -0.0 -0.9 -0.2 -0.2 0.3
Illnesses of father: None of the above (group 1) 9.3 11.5 19.4 3.6 3.4 3.4 3.8 -2.1 3.7 2.8 3.6 3.6 4.4 2.6 3.7 2.7 3.8 3.6 3.8 2.7 3.8 -3.1 3.7 3.7 1.1 3.3 3.7 3.5 3.5 3.4 2.4 3.9 3.2 3.5
Smoking status: Current 0.9 1.4 4.2 -0.4 -0.8 -1.2 -0.5 1.8 -0.7 -1.8 -0.3 -0.9 -0.7 -2.0 -1.5 -1.9 -1.3 -0.3 -1.1 -1.4 -1.6 0.2 -0.8 -0.5 -0.7 -2.0 -1.2 -1.2 -1.3 -0.9 -1.1 -0.7 -0.8 -1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 2.2 -0.5 -0.6 -1.2 0.9 0.7 0.6 0.9 -0.6 -0.6 -0.6 -0.9 -0.7 -0.9 -0.2 -0.5 -0.6 -0.8 -0.8 -0.4 -0.5 -0.5 1.5 -0.9 0.2 -0.4 -0.7 -0.6 -0.9 -0.1 0.8 -0.7
Whole body water mass 10.5 60.0 79.7 7.9 6.4 8.9 7.3 -8.2 7.7 5.5 7.8 7.3 7.6 8.7 8.6 8.9 7.5 7.8 8.5 8.6 8.3 -6.3 8.1 8.0 3.7 8.5 8.2 8.9 8.6 8.7 5.3 7.8 5.7 7.9
Leg predicted mass (right) 10.6 56.4 75.0 7.6 5.7 8.5 6.9 -8.0 7.5 4.9 7.5 7.2 7.1 8.6 8.4 8.7 7.3 7.6 8.0 8.3 8.2 -6.4 7.8 7.7 3.2 8.5 8.0 8.6 8.5 8.4 5.3 7.6 5.9 7.8
Arm fat mass (left) 2.4 9.8 16.2 2.9 1.3 3.7 2.8 -3.1 3.2 2.1 3.0 3.2 2.8 3.6 3.6 3.5 2.8 2.9 3.3 3.3 3.7 -3.2 3.3 3.0 1.6 4.0 3.2 3.5 3.6 3.4 2.2 3.2 2.4 4.0
Number of self-reported non-cancer illnesses 2.6 4.6 11.9 -2.2 -3.5 -2.4 -2.2 1.6 -2.0 -1.6 -2.3 -2.1 -2.0 -1.8 -2.5 -1.9 -2.0 -2.3 -2.5 -2.9 -2.3 1.9 -2.2 -2.2 -1.4 -2.2 -1.9 -2.3 -2.1 -2.2 -1.7 -2.0 -1.2 -1.9
Average weekly champagne plus white wine intake 0.4 0.5 3.3 -0.9 -1.0 -0.6 -0.1 -0.6 -0.4 -0.7 -0.9 -0.7 -0.3 0.0 -0.3 0.2 -1.1 -1.0 -0.8 -0.4 -0.2 1.3 -0.7 -0.7 -0.8 -0.2 -0.5 -0.1 -0.5 -0.4 -1.8 -0.4 -0.6 0.2
Miserableness 1.2 2.1 5.7 -1.7 -1.2 -1.6 -1.2 0.2 -1.3 -1.6 -1.8 -1.2 -1.9 -0.6 -1.7 -0.6 -2.0 -1.8 -1.9 -1.1 -1.6 1.1 -1.7 -1.7 -0.7 -1.2 -1.6 -1.3 -1.2 -1.3 -2.4 -1.6 -1.1 -0.4
Guilty feelings 0.6 0.9 2.4 -0.6 -0.0 -0.9 -1.6 0.5 -1.0 -0.7 -0.7 -1.0 -1.0 -0.8 -1.2 -0.9 -0.8 -0.7 -1.1 -1.2 -1.3 1.0 -0.9 -0.7 -1.0 -1.1 -1.5 -1.1 -1.1 -0.8 -0.3 -0.7 -0.2 -1.3
Wears glasses or contact lenses 0.2 0.2 1.6 -0.4 -0.5 -0.4 -0.2 0.2 -0.0 -0.2 -0.4 -0.3 0.2 -0.5 -0.4 -0.4 -0.5 -0.9 -0.2 -0.8 -0.1 0.2 -0.3 -0.5 0.2 -0.3 -0.2 -0.5 -0.8 -0.5 -1.2 -0.5 0.3 -0.2
Ever taken oral contraceptive pill 1.8 2.0 4.3 -1.2 -0.9 -1.6 -1.3 2.1 -1.4 -1.4 -1.2 -0.9 -1.1 -1.9 -1.3 -1.8 -1.6 -1.2 -1.6 -1.2 -1.1 1.3 -1.2 -1.2 -1.9 -1.3 -1.2 -1.5 -1.5 -1.5 -0.9 -1.5 -1.7 -1.0
Hearing aid user 1.3 1.5 3.6 1.4 0.1 1.4 0.9 -1.3 0.7 1.9 1.5 1.7 0.7 1.1 1.3 1.2 1.6 1.0 1.4 1.0 1.3 -0.7 1.4 1.5 -0.7 1.2 1.4 1.2 1.2 1.4 0.5 1.2 1.1 0.9
Mother’s age at death 5.2 6.5 9.3 2.5 2.1 2.7 3.0 -2.5 2.6 2.5 2.5 1.9 2.2 2.4 2.9 2.7 2.5 2.5 2.7 3.0 2.7 -2.0 2.6 2.6 3.0 2.5 2.2 3.0 2.4 2.7 1.8 3.0 2.8 1.7
Financial situation satisfaction 4.2 5.3 9.7 2.5 2.7 2.4 2.0 -2.0 2.0 1.0 2.5 2.2 2.6 2.1 2.4 2.2 2.3 2.5 2.5 2.3 2.4 -2.4 2.6 2.5 3.1 2.4 2.2 2.3 2.3 2.4 0.7 2.1 2.4 1.8
Tinnitus: Yes, now most or all of the time 3.4 3.9 7.1 2.1 0.4 2.2 1.9 -1.6 2.3 1.6 2.0 1.9 1.7 1.9 2.2 1.7 2.1 1.9 2.1 1.9 2.1 -2.1 2.1 2.1 0.3 2.3 2.3 2.1 2.1 2.0 2.7 2.2 1.8 1.9
Commuting to job workplace: Public transport 0.9 1.1 2.7 -1.3 -1.7 -0.8 -1.1 0.8 -1.3 -0.0 -1.1 -1.1 -1.1 -1.0 -0.6 -0.7 -1.6 -1.1 -0.8 -0.4 -0.3 1.3 -0.9 -1.3 -0.3 -0.7 -0.8 -1.0 -1.0 -1.2 -1.6 -1.3 -1.2 -1.0
Eye problems/disorders: Glaucoma 1.4 1.7 5.2 -1.3 -0.5 -1.7 -1.1 1.9 -0.9 -2.3 -1.3 -0.6 -1.4 -1.6 -1.4 -2.0 -1.4 -1.4 -1.6 -1.2 -1.4 0.3 -1.3 -1.3 0.2 -1.1 -0.7 -1.5 -1.3 -1.6 0.4 -1.2 -0.6 -1.3
Medication: Blood pressure 2.2 4.2 7.3 -2.2 -2.7 -2.1 -1.6 1.8 -1.8 -2.1 -2.1 -2.2 -2.5 -1.8 -2.4 -2.1 -1.8 -1.8 -2.1 -1.9 -2.5 1.7 -2.3 -2.2 -1.7 -2.0 -1.9 -2.1 -1.8 -2.2 -0.7 -2.3 -1.5 -2.2
Pain type(s) experienced in last month: Hip pain 0.4 0.5 5.6 -0.6 -2.4 -0.8 -0.4 1.1 -0.5 -0.2 -0.5 -0.6 -0.8 -0.6 -0.5 -0.9 -0.7 -0.9 -1.0 -0.8 -0.4 -0.4 -0.3 -0.4 -0.3 -0.0 -0.5 -0.7 -0.5 -0.6 -0.6 -0.0 0.6 -0.3
Supplements: Fish oil (including cod liver oil) 4.2 5.5 8.9 -2.7 -2.6 -2.3 -1.9 2.0 -2.2 -1.8 -2.7 -2.5 -2.6 -2.0 -2.5 -2.1 -2.4 -2.9 -2.3 -1.6 -2.7 2.2 -2.8 -2.7 -1.1 -2.4 -2.2 -2.3 -2.6 -2.7 -0.6 -2.8 -2.1 -3.0
High cholesterol (Self-reported) 1.4 2.5 7.8 -1.8 -2.8 -1.3 -1.7 1.5 -1.7 -1.3 -1.6 -1.6 -1.1 -1.4 -1.4 -1.3 -1.9 -1.7 -1.5 -1.8 -1.2 1.1 -1.6 -1.8 -1.5 -1.2 -1.6 -1.6 -1.3 -1.7 -1.6 -1.7 -1.3 -0.9
Medication: Bendroflumethiazide 3.4 5.2 11.9 -2.5 -3.4 -2.3 -1.7 2.0 -2.0 -1.7 -2.5 -2.3 -2.5 -2.1 -2.5 -2.1 -2.1 -2.4 -2.3 -2.6 -2.5 1.5 -2.5 -2.5 -2.3 -2.5 -2.3 -2.3 -2.2 -2.4 -1.6 -2.2 -1.6 -2.2
Medication: Paracetamol 4.8 7.5 13.8 -2.6 -2.5 -3.2 -3.1 2.8 -2.9 -1.5 -2.5 -2.6 -2.5 -3.0 -3.1 -3.0 -2.9 -2.3 -3.2 -3.7 -2.9 1.9 -2.6 -2.6 -1.7 -3.0 -2.7 -3.2 -2.9 -2.8 -2.4 -2.8 -1.7 -2.6
Medication: Lisinopril 0.2 0.3 1.7 -0.3 0.6 -0.4 0.4 0.8 0.2 -0.0 -0.3 -0.5 -0.3 -0.8 -0.3 -0.7 -0.4 0.3 -0.2 0.1 -0.3 1.3 -0.3 -0.4 0.2 -0.6 -1.1 -0.3 -0.2 -0.5 0.5 -0.6 -0.6 -0.9
Medication: Atorvastatin 0.5 0.6 2.2 1.1 -0.7 0.7 0.1 -0.3 0.2 0.8 1.2 0.8 0.7 0.7 0.5 0.6 0.5 1.4 0.6 -0.1 0.6 -1.1 1.1 1.0 -0.7 0.4 0.3 0.5 0.7 0.9 -0.5 0.4 1.5 0.2
Illnesses of father: High blood pressure 2.5 3.0 7.9 -2.2 -1.7 -1.1 -2.7 -0.9 -2.4 -0.8 -2.3 -2.5 -1.9 0.3 -1.6 0.2 -2.1 -2.2 -1.9 -0.9 -1.8 1.4 -2.1 -2.2 -0.4 -1.1 -1.6 -1.1 -0.9 -1.3 -1.7 -2.5 -2.8 -0.9
Alcohol drinker status: Never 1.3 1.6 3.8 -1.2 -1.3 -1.4 -1.2 0.6 -1.2 -1.1 -1.3 -1.6 -1.1 -1.3 -1.5 -1.1 -1.3 -1.0 -1.3 -1.0 -1.5 2.0 -1.4 -1.2 -0.1 -1.7 -1.3 -1.3 -1.3 -1.2 -1.5 -1.0 -1.2 -0.8
Ever smoked 3.1 5.4 8.3 -2.7 -2.2 -2.6 -1.3 2.2 -2.0 -0.6 -2.7 -2.6 -2.0 -2.3 -2.6 -2.4 -2.5 -2.5 -2.5 -2.1 -2.8 1.6 -2.7 -2.6 -0.9 -2.7 -2.4 -2.2 -2.5 -2.6 -1.2 -2.6 -2.2 -2.9
Basal metabolic rate 9.9 54.9 73.3 7.5 5.9 8.6 6.9 -7.9 7.3 5.1 7.4 7.0 7.2 8.4 8.2 8.5 7.1 7.4 8.1 8.2 8.0 -6.2 7.7 7.6 3.5 8.3 7.8 8.5 8.3 8.3 5.2 7.4 5.5 7.7
Leg fat percentage (left) 0.1 0.3 4.8 -0.6 -2.2 -0.1 -0.5 0.3 -0.3 -0.9 -0.4 -0.2 -0.4 -0.0 -0.3 -0.2 -0.7 -0.6 -0.5 -0.6 -0.2 -0.5 -0.4 -0.6 -0.4 0.2 -0.5 -0.4 -0.2 -0.4 -0.4 -0.3 -0.3 0.4
Arm fat-free mass (left) 9.5 48.0 65.9 7.2 5.7 8.1 6.6 -7.1 6.9 4.8 7.1 6.6 6.9 7.6 7.7 7.8 6.9 7.0 7.7 7.6 7.4 -5.5 7.2 7.2 3.2 7.5 7.3 7.9 7.6 7.8 5.0 7.0 5.0 7.0
Number of operations (self-reported) 0.4 0.6 1.8 -0.5 -0.3 -1.3 -0.4 1.0 -0.4 -0.0 -0.6 -0.7 -1.0 -1.0 -0.9 -1.0 -0.4 -0.7 -0.9 -0.9 -0.8 1.0 -0.5 -0.6 0.5 -1.0 -0.8 -0.9 -0.6 -0.7 -0.9 -0.9 0.4 -1.3
Average weekly beer plus cider intake 6.8 9.9 15.8 -3.2 -2.8 -3.2 -2.8 2.8 -2.9 -1.5 -3.1 -3.5 -2.6 -3.2 -3.7 -3.1 -2.9 -3.2 -3.4 -3.9 -3.8 2.8 -3.4 -3.2 -2.1 -4.0 -3.4 -3.2 -3.2 -3.2 -2.3 -3.4 -3.0 -3.3
Irritability 0.8 1.4 3.4 -1.2 -1.7 -1.3 -0.8 1.7 -0.9 -1.9 -1.1 -0.8 -1.4 -1.4 -1.1 -1.6 -1.1 -1.2 -1.4 -1.3 -0.9 0.5 -1.1 -1.2 -0.8 -0.6 -1.0 -1.3 -1.2 -1.4 0.0 -1.0 -0.5 -0.9
Risk taking 4.7 6.8 10.5 -3.1 -2.3 -2.6 -2.8 2.4 -2.8 -0.7 -3.0 -2.9 -2.8 -2.5 -2.5 -2.5 -3.1 -3.2 -2.7 -2.5 -2.5 1.8 -2.9 -3.0 -3.0 -2.4 -2.5 -2.7 -2.4 -2.9 -1.4 -2.8 -2.9 -1.9
Ever had prostate specific antigen (PSA) test 5.0 5.8 8.7 2.1 2.1 2.4 2.7 -2.7 2.8 2.8 2.0 2.0 2.7 2.5 2.8 2.7 1.7 2.1 2.6 2.1 3.0 -1.9 2.5 2.1 2.8 2.7 2.1 2.6 2.1 2.4 -0.3 2.5 2.9 2.2
Fractured/broken bones in last 5 years 0.6 0.7 2.4 0.9 1.6 1.2 0.4 -0.6 0.4 -0.1 0.9 0.9 0.3 0.7 1.0 0.8 0.3 0.7 0.9 1.4 0.8 -0.3 0.8 0.9 -1.2 0.8 0.4 0.8 1.1 0.9 1.2 1.0 -0.2 0.8
Age started oral contraceptive pill 0.4 0.5 3.1 -0.3 -0.2 -0.1 -1.0 0.6 -0.9 -0.5 -0.2 0.5 -0.0 -0.8 -0.2 -0.4 0.1 -0.0 -0.1 -0.3 0.2 1.8 -0.2 -0.4 -1.5 -0.5 -0.5 -0.6 -0.8 -0.5 -1.0 -1.0 -0.6 -0.9
Diastolic blood pressure, automated reading 0.1 0.4 1.6 -0.6 -1.3 -0.1 -0.9 0.0 -0.9 -1.1 -0.5 -0.3 -1.1 0.0 -0.6 0.0 -0.8 -0.7 -0.3 -0.3 -0.6 -0.0 -0.6 -0.6 -0.9 -0.5 -0.3 -0.5 -0.2 -0.3 -0.5 -0.7 -1.2 -0.1
Ever depressed for a whole week 0.2 0.2 1.0 -0.4 -0.2 -0.5 -0.3 0.6 -0.4 -0.4 -0.5 -0.3 -0.5 -0.0 -0.2 -0.3 -0.9 -0.7 -0.6 -0.1 -0.0 0.4 -0.2 -0.4 0.3 0.5 -0.7 -0.4 0.4 -0.4 1.0 -0.3 -0.1 0.2
Unable to work because of sickness or disability 0.2 0.3 1.3 0.6 -1.1 0.3 -0.8 -0.2 -0.0 -0.9 0.5 1.1 -0.4 0.3 -0.1 0.2 0.3 0.3 0.2 0.3 -0.1 -0.4 0.4 0.5 -0.3 0.2 0.3 -0.0 0.1 0.4 0.4 0.6 0.7 0.8
Commuting to job workplace: Cycle 0.5 0.6 3.5 -0.7 -0.9 -0.9 -0.4 0.7 -0.5 -1.9 -0.6 -0.7 -1.7 -0.5 -1.0 -0.8 -0.8 -0.7 -0.9 -0.1 -1.2 -0.0 -0.8 -0.6 0.7 -0.8 -0.5 -0.6 -0.2 -0.7 0.1 -0.4 -0.5 -0.5
Myopia 0.3 0.4 2.2 0.4 0.9 0.6 0.0 -1.5 0.2 0.9 0.4 0.5 0.7 0.7 0.5 0.9 0.7 0.6 0.5 0.4 0.4 -0.3 0.5 0.4 0.1 0.1 0.5 0.7 0.5 0.7 -1.1 0.3 0.4 0.2
Vascular/heart problems diagnosed by doctor 2.3 6.3 16.6 2.4 4.1 2.6 2.4 -2.9 2.1 2.8 2.2 1.9 2.9 2.6 2.8 3.0 2.5 2.2 2.8 3.2 2.5 -1.6 2.4 2.4 2.6 2.3 1.8 2.9 2.2 2.7 1.5 2.5 1.4 1.8
Cholesterol lowering medication 0.3 0.4 2.0 -0.8 -1.4 -0.3 -0.4 0.1 -0.4 -0.2 -0.7 -0.3 -0.6 -0.1 -0.6 -0.0 -1.0 -0.6 -0.5 -0.7 -0.5 0.7 -0.6 -0.9 -0.1 -0.4 -0.8 -0.5 -0.5 -0.5 -1.4 -1.1 -0.2 -0.2
Medication: Omeprazole (e.g. Zanprol) 1.1 1.3 4.2 0.8 1.1 0.9 1.1 -1.6 1.1 1.2 0.6 0.6 0.7 1.6 1.3 1.7 1.0 0.7 0.8 1.4 1.4 -1.0 1.0 0.7 2.0 1.6 0.9 1.2 1.1 1.1 0.8 0.7 1.0 1.2
Pain experienced in last month 0.2 0.3 2.4 0.1 1.5 0.7 0.3 -0.2 0.1 -0.4 0.1 0.5 0.9 0.1 0.9 0.6 -0.1 0.5 0.6 0.7 1.0 1.1 0.3 0.1 -0.4 0.5 -0.2 0.5 0.4 0.2 0.6 -0.2 -0.5 -0.0
Supplements: Calcium 1.3 1.4 2.4 -1.1 -0.4 -1.3 -1.4 1.2 -1.2 -1.5 -1.2 -1.1 -0.6 -1.4 -1.1 -1.3 -0.8 -1.4 -1.2 -1.1 -1.1 1.5 -1.1 -1.1 0.1 -1.3 -1.4 -1.3 -1.4 -1.3 -0.7 -0.7 -0.8 -1.6
Basal cell carcinoma (self-reported) 1.0 1.1 3.2 -0.6 -1.0 -1.1 -1.5 1.2 -1.0 0.2 -0.7 -0.4 -1.1 -1.2 -1.4 -1.3 -0.9 -0.7 -0.9 -1.0 -1.3 1.5 -1.1 -0.7 -1.8 -1.2 -0.6 -1.2 -1.2 -1.0 -0.0 -0.8 -1.6 -0.4
Heart attack/myocardial infarction (self-reported) 0.6 0.8 3.8 -0.8 -1.9 -1.1 -1.3 0.4 -0.8 -1.0 -0.8 -0.7 -0.6 -0.6 -0.9 -0.9 -0.7 -1.0 -1.3 -1.5 -0.8 0.3 -0.8 -0.8 -0.4 -0.3 0.2 -0.9 -0.9 -0.9 0.5 -0.6 -0.2 -0.4
Deep venous thrombosis (DVT) (self-reported) 1.8 2.3 7.9 1.4 1.5 1.4 1.0 -1.6 1.4 1.1 1.4 1.0 1.9 1.4 1.8 1.6 1.5 1.4 1.8 1.6 1.9 -1.1 1.6 1.5 2.8 1.7 1.0 1.5 1.3 1.4 0.3 1.6 1.7 1.0
Heart disease (siblings) 0.1 0.1 1.1 -0.1 -0.8 -0.0 -0.7 -0.6 -0.2 -1.0 -0.1 0.1 0.4 0.2 -0.1 0.2 -0.1 -0.2 -0.4 -0.4 -0.1 0.3 -0.1 -0.1 -0.0 0.1 -0.0 -0.1 -0.2 0.0 -0.4 -0.1 0.5 -0.2
Alcohol drinker status: Previous 0.3 0.4 2.1 0.4 -0.3 0.4 -0.8 -0.7 -0.2 0.2 0.3 0.6 0.1 1.0 0.5 0.9 -0.3 0.8 0.2 0.3 0.6 -0.5 0.4 0.2 0.1 0.9 0.6 0.3 1.1 0.6 0.5 -0.4 -0.0 1.4
Pack years of smoking 0.8 1.2 3.0 1.1 -0.2 1.1 -0.1 -1.1 0.8 -0.4 1.1 1.2 1.2 1.3 1.1 1.2 0.7 1.4 0.6 0.3 1.2 -1.1 1.2 1.2 -1.7 1.3 1.3 1.0 1.0 1.3 0.1 1.5 1.2 1.7
Impedance of whole body 3.8 19.3 26.7 -4.3 -2.2 -5.0 -4.4 4.4 -4.4 -3.2 -4.3 -3.9 -4.2 -4.9 -5.0 -4.9 -4.0 -4.2 -4.8 -4.9 -4.8 4.1 -4.6 -4.4 -2.3 -5.2 -4.8 -5.0 -5.1 -4.8 -3.4 -4.6 -3.5 -4.8
Leg fat mass (left) 1.9 7.3 11.9 2.5 0.6 3.3 2.4 -2.8 2.7 1.4 2.6 2.7 2.5 3.2 3.1 3.2 2.4 2.4 2.8 2.7 3.1 -2.9 2.8 2.6 0.9 3.5 2.7 3.0 3.1 3.0 1.7 2.8 2.1 3.4
Arm predicted mass (left) 9.6 48.8 66.4 7.2 5.6 8.2 6.6 -7.3 6.9 4.9 7.2 6.7 6.9 7.7 7.8 7.8 6.9 7.1 7.7 7.6 7.5 -5.7 7.4 7.3 3.3 7.6 7.3 8.0 7.7 7.9 4.9 7.1 5.3 7.0