Best TWAS P=2.19e-17 · Best GWAS P=1.29e-18 conditioned to 0.00286
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Brain Lower Grade Glioma | BCAR1 | 0.06 | 0.03 | enet | 4 | 0.04 | 1.4e-05 | -8.8 | -8.5 | 2.2e-17 | 0.86 | 0.00 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | BCAR1 | 0.04 | 0.02 | enet | 8 | 0.03 | 5.1e-04 | 8.0 | -7.0 | 3.3e-12 | 0.69 | 0.02 | 0.70 | FALSE |