TWAS hub - BCAR1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.1830	0.0570	1.1e-05	0.131	NA	0.065	NA	0.112	1.1e-07	NA	1.9e-04	NA	9.8e-07
2	GTEx	Artery Tibial	0.0705	0.0319	4.3e-03	0.058	NA	0.021	NA	0.043	2.4e-05	NA	8.5e-03	NA	2.4e-04
3	GTEx	Brain Cerebellum	0.1830	0.0770	6.2e-03	0.077	NA	0.092	NA	0.053	2.7e-03	NA	1.1e-03	NA	1.1e-02
4	GTEx	Esophagus Mucosa	0.1630	0.0410	1.7e-07	0.132	NA	0.098	NA	0.138	4.1e-09	NA	4.3e-07	NA	1.8e-09
5	GTEx	Nerve Tibial	0.2260	0.0562	9.4e-07	0.117	NA	0.125	NA	0.132	1.2e-08	NA	4.0e-09	NA	1.4e-09
6	GTEx	Pancreas	0.1210	0.0530	9.9e-03	0.136	NA	0.070	NA	0.094	2.5e-06	NA	7.0e-04	NA	8.6e-05
7	TCGA	Brain Lower Grade Glioma	0.0625	0.0291	6.1e-04	0.034	0.026	0.042	NA	0.029	9.4e-05	0.00059	1.4e-05	NA	2.5e-04
8	TCGA	Lung Adenocarcinoma	0.0433	0.0243	4.6e-03	0.020	0.023	0.025	NA	0.018	1.8e-03	0.00097	5.1e-04	NA	2.7e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Lung FEV1/FVC ratio	32.6	165.4	331.5	-18.2	-18.0	17.0	17.7	-0.6	4.9	2.4	5.8
Systolic Blood Pressure	11.9	59.4	116.6	10.7	10.8	-9.0	-10.2	-2.2	-6.3	-1.1	-3.7
Headache pain in last month	9.4	16.2	29.6	-5.3	-5.4	4.8	5.3	3.0	3.2	0.3	1.1
Coronary Artery Disease (CAD)	8.8	10.5	16.3	4.0	3.7	-3.3	-3.8	-1.8	-3.2	-2.2	-3.2
Systolic blood pressure, automated reading	8.5	24.8	46.5	6.7	6.6	-6.8	-6.7	-1.8	-3.8	0.0	-1.1
Heart disease (siblings)	8.1	10.0	15.8	4.0	3.9	-3.3	-3.6	1.2	-2.7	-2.3	-3.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	8.0	16.9	31.9	-5.4	-5.6	4.7	5.5	-0.7	2.5	2.5	3.1
Angina	7.6	9.9	14.2	3.5	3.2	-3.8	-2.9	-1.1	-3.4	-2.7	-3.8
High blood pressure (mother)	7.6	10.7	22.8	4.6	4.8	-4.2	-4.4	1.4	-1.1	-0.1	-1.2
Angina (self-reported)	7.6	10.0	15.4	3.4	3.2	-3.9	-2.9	-1.2	-3.6	-2.6	-3.6
Birth weight of first child	7.0	12.7	27.6	-5.1	-5.2	3.0	5.2	-0.9	1.8	0.9	2.7
Pulse wave peak to peak time	6.6	7.7	11.4	3.0	3.3	-2.5	-3.4	0.2	-2.9	-3.1	-2.5
Ulcerative Colitis	6.3	9.2	19.2	-4.1	-3.7	4.4	3.7	0.1	1.7	1.0	2.4
Peak expiratory flow (PEF)	6.2	14.4	27.5	-5.2	-5.1	5.2	5.0	1.2	1.9	1.0	1.9
Emphysema/chronic bronchitis	6.1	6.9	11.2	3.1	3.4	-3.3	-3.0	-1.2	-1.9	-1.6	-2.6
Pulse wave Arterial Stiffness index	5.7	6.7	10.1	-2.7	-3.0	2.2	3.1	0.0	2.7	3.2	2.4
Pulse wave reflection index	5.5	6.8	19.2	-1.6	-2.0	0.5	2.3	-1.2	3.2	4.4	3.4
Allergy or Eczema	5.1	13.4	24.5	-5.0	-4.7	4.6	4.8	1.2	2.5	1.6	2.5
Birth weight	5.0	10.8	17.3	-4.0	-3.5	4.2	3.4	-1.0	2.6	2.4	4.0
Hayfever, allergic rhinitis or eczema	4.9	10.6	17.1	-4.1	-3.9	3.9	3.9	0.9	2.9	1.9	3.0
Medication: Cholesterol lowering	4.7	7.4	10.6	3.3	2.8	-3.1	-2.5	-0.6	-3.0	-2.1	-3.2
Impedance of leg (left)	4.6	22.6	71.9	2.4	1.8	-0.7	-2.5	4.9	-4.5	-8.5	-7.0
Medication: Blood pressure	4.6	8.7	16.0	4.0	3.9	-3.8	-3.6	0.3	-2.1	-1.0	-2.4
Medication: Paracetamol	4.3	7.1	13.3	-3.6	-3.6	2.3	3.4	3.3	1.3	-0.8	0.2
Impedance of leg (right)	4.2	20.6	63.5	2.3	1.7	-0.7	-2.2	5.4	-3.7	-8.0	-6.7
Medication: Ibuprofen	4.2	5.0	9.2	-2.4	-2.3	2.3	2.4	3.0	2.2	1.0	1.7
Mouth/teeth dental problems: Loose teeth	4.1	4.8	9.1	-1.9	-1.9	3.0	2.5	-0.4	2.3	2.9	1.6
Ever had prostate specific antigen (PSA) test	4.1	4.7	11.3	2.8	2.6	-3.4	-2.7	-0.1	-1.9	0.0	-0.5
Illnesses of father: None of the above (group 1)	4.0	5.0	8.3	-2.9	-2.8	1.9	2.6	1.2	1.5	1.3	2.7
Impedance of whole body	3.9	20.1	57.8	2.6	2.2	-1.2	-3.1	4.5	-4.4	-7.6	-6.4
Supplements: Fish oil (including cod liver oil)	3.7	4.8	11.2	2.3	2.0	-1.7	-2.2	0.7	-1.6	-3.4	-2.7
Medication: Bendroflumethiazide	3.7	5.6	9.6	2.9	3.1	-2.7	-2.8	0.5	-2.6	-0.3	-2.2
Ulcerative Colitis (UC)	3.6	6.7	14.2	-3.8	-3.3	3.7	3.2	0.1	1.3	0.7	1.6
Blood Platelet Count	3.6	41.6	78.9	8.9	8.8	-7.6	-8.9	-3.7	-4.5	0.3	-2.3
Cardiovascular Disease	3.6	11.8	25.3	5.0	4.7	-4.6	-3.7	0.2	-2.4	-1.2	-2.1
Medication: Ibuprofen (e.g. Nurofen)	3.5	4.4	8.7	-2.2	-2.1	2.1	2.1	3.0	2.4	0.7	1.5
Number of full sisters	3.4	4.2	11.3	-1.8	-1.9	1.7	1.9	1.4	3.4	1.6	2.0
High blood pressure	3.3	9.1	19.8	4.4	4.3	-4.4	-3.4	-0.3	-1.7	-0.2	-1.0
Medication: Atenolol	3.3	4.1	6.6	2.4	2.5	-2.6	-2.4	-0.5	-2.2	-1.0	-1.5
Medication: Simvastatin	3.2	4.7	8.8	2.2	1.9	-2.2	-2.0	-0.3	-2.3	-2.4	-3.0
Hypertension (Self-reported)	3.2	9.0	19.8	4.5	4.3	-4.3	-3.3	-0.2	-1.4	0.2	-1.0
Vascular/heart problems diagnosed by doctor	3.2	8.8	18.6	-4.2	-4.1	4.3	3.1	0.4	1.8	0.7	2.0
Supplements: Glucosamine	3.1	4.1	9.8	2.8	2.7	-2.5	-3.1	-1.1	-0.4	0.0	-0.4
Illnesses of mother	3.1	3.8	7.8	-2.4	-2.8	1.8	2.5	-0.3	2.1	0.3	1.7
Average weekly spirits intake	2.9	3.6	9.1	-2.7	-2.9	1.7	3.0	1.1	0.1	-0.3	0.4
High cholesterol (Self-reported)	2.9	5.1	8.6	2.6	2.3	-2.3	-2.0	-0.9	-2.9	-1.7	-2.6
Forced expiratory volume in 1-second (FEV1), Best measure	2.8	8.9	24.5	-3.5	-3.8	4.9	3.7	1.7	1.4	1.0	0.9
Medication for cholesterol, blood pressure or diabetes	2.8	4.6	9.1	-3.0	-2.8	2.8	2.0	-0.1	1.4	1.0	2.2
Allergy	2.7	6.2	12.2	3.3	3.0	-2.5	-3.5	-0.7	-2.6	-1.0	-1.7
Forced expiratory volume in 1-second (FEV1)	2.7	9.0	22.0	-3.7	-3.9	4.7	3.9	1.5	1.2	0.9	0.9
Medication: Blood pressure	2.7	4.8	9.5	3.0	3.1	-2.4	-2.2	-1.1	-2.4	-0.5	-1.5
Illnesses of father: Heart disease	2.7	3.7	10.0	1.8	1.7	-1.2	-1.5	-1.0	-2.0	-2.1	-3.2
Medication: Amlodipine	2.5	3.5	6.0	2.3	2.1	-2.4	-2.0	-1.2	-2.4	-0.1	-1.0
Medication for cholesterol	2.5	3.7	8.8	-2.6	-2.7	3.0	2.3	0.2	0.8	-0.7	0.6
Cholesterol lowering medication	2.5	3.7	8.5	1.7	1.7	-2.1	-1.3	-0.2	-2.3	-2.0	-2.9
Diverticular disease/diverticulitis (self-reported)	2.4	2.8	6.1	-1.9	-1.8	0.5	2.3	1.1	2.5	1.2	1.1
Chronic bronchitis/emphysema (father)	2.4	2.8	6.1	2.2	2.5	-1.5	-2.4	1.1	-1.0	0.5	-0.9
Illnesses of siblings	2.4	3.4	8.6	-2.5	-2.3	2.9	1.7	-0.2	1.6	-0.4	1.0
Impedance of arm (right)	2.4	11.1	28.0	2.0	2.0	-1.3	-2.7	3.8	-3.5	-5.3	-4.1
Impedance of arm (left)	2.4	10.9	30.1	1.9	1.8	-1.1	-2.7	3.2	-3.5	-5.5	-4.4
Glaucoma (self-reported)	2.4	2.8	8.0	-1.8	-1.9	1.0	1.8	0.5	2.8	1.4	1.0
Irritable Bowel Disease (IBD)	2.3	5.4	11.8	-3.4	-3.0	2.8	2.7	-1.8	0.5	1.1	1.7
Medication for pain relief, constipation, heartburn	2.3	3.9	9.4	2.0	2.2	-1.3	-3.1	-3.1	-0.5	0.9	0.9
Heart disease (mother)	2.3	2.7	6.1	1.8	1.8	-0.7	-1.0	-0.4	-2.5	-1.2	-2.5
Eye problems/disorders: Glaucoma	2.3	2.7	5.1	-2.1	-1.8	1.7	1.8	-0.1	2.3	1.3	1.1
Eye problems/disorders: Cataract	2.2	2.5	7.5	-1.9	-2.1	1.0	2.7	-0.4	1.7	-0.7	-0.4
Tinnitus: Yes, now most or all of the time	2.2	2.5	8.8	0.4	0.3	-0.4	-0.7	-0.2	-2.1	-3.0	-2.5
Illnesses of father: High blood pressure	2.2	2.7	6.6	2.5	2.6	-2.0	-2.1	0.7	-0.2	0.2	-0.4
High blood pressure (siblings)	2.1	3.0	6.2	2.5	2.2	-2.4	-1.8	0.8	-1.3	1.3	-0.4
Comparative height size at age 10	2.1	11.6	23.3	4.8	4.6	-3.8	-4.7	2.7	-0.7	-0.6	-2.1
Medication: Paracetamol	2.1	3.2	6.5	-2.4	-2.6	1.4	2.4	2.3	0.6	-0.6	0.3
Pain experienced in last month	2.1	3.5	7.2	2.3	2.7	-1.4	-2.2	-2.0	-2.1	0.5	0.2
Eye problems/disorders: None of the above	2.0	2.3	6.2	1.6	1.8	-0.7	-2.5	1.2	-2.1	-0.1	0.3
Hand grip strength (right)	1.9	5.0	11.7	3.4	3.3	-2.5	-3.0	-0.7	-0.6	1.3	0.1
Bilateral oophorectomy (both ovaries removed)	1.9	2.2	5.1	-0.9	-1.1	1.0	1.4	-1.1	1.9	2.3	1.6
Number of incorrect matches in round	1.9	3.1	4.9	2.0	2.0	-1.5	-2.0	0.5	-1.8	-2.2	-1.4
Medication: Aspirin	1.9	2.5	8.2	1.0	0.8	-1.0	-0.1	-1.7	-2.1	-1.3	-2.9
Frequency of tenseness / restlessness in last 2 weeks	1.8	2.8	5.8	-2.4	-2.4	1.9	2.2	0.2	0.1	-1.6	-0.1
Hair/balding pattern: Pattern 2	1.8	2.2	4.9	1.9	1.8	-2.2	-1.6	-1.3	-0.7	1.1	0.5
Exposure to tobacco smoke at home	1.8	2.1	5.2	-2.0	-2.3	1.0	2.2	0.8	0.5	-0.1	0.7
Hair/balding pattern: Pattern 4	1.8	4.4	7.7	-2.3	-2.1	2.8	1.6	-2.4	0.2	1.9	2.4
Medication: Aspirin	1.8	2.3	6.0	1.1	0.9	-1.3	-0.4	-1.8	-2.2	-0.8	-2.5
HbA1C	1.7	1.8	6.3	0.8	1.0	-0.6	-1.4	-1.2	-0.6	-1.7	-2.5
Primary Biliary Cirrhosis	1.7	2.4	4.1	-1.2	-0.8	2.0	1.1	-1.5	1.4	1.9	2.0
Type 2 Diabetes (T2D) (2012)	1.7	2.0	6.9	1.0	0.7	-1.7	-0.5	-0.6	-1.0	-2.6	-1.8
Pain all over the body in last month	1.7	1.9	3.4	-1.5	-1.9	1.6	1.5	-0.9	1.6	0.6	0.9
Qualifications: NVQ or HND or HNC or equivalent	1.7	2.1	4.3	-1.7	-1.6	2.1	1.8	-0.2	1.3	1.0	1.2
Mineral and other dietary supplements	1.7	2.2	4.6	-2.0	-1.8	1.6	2.1	0.9	0.6	0.9	1.1
BMI	1.6	9.0	13.4	-3.7	-3.2	2.6	3.5	-1.6	2.2	3.4	3.2
Hand grip strength (left)	1.6	4.2	11.2	3.3	2.9	-2.2	-2.7	-0.6	-0.2	1.1	0.6
Body mass index (BMI)	1.6	6.7	10.8	-3.3	-2.8	2.2	3.1	-1.8	1.5	2.9	2.6
Pulse rate	1.6	2.6	8.7	-1.0	-0.7	1.5	0.9	2.0	-0.0	-2.9	-1.9
Migraine (self-reported)	1.6	2.0	4.5	-1.6	-2.1	2.0	1.6	1.2	0.1	-0.9	-0.3
Back pain experienced in last month	1.6	2.3	7.6	-1.1	-1.2	1.1	0.8	1.6	0.4	-1.9	-2.8
Fractured/broken bones in last 5 years	1.6	2.1	5.6	2.0	1.5	-2.4	-1.1	-0.3	-0.8	0.2	-1.6
Unable to work because of sickness or disability	1.6	2.1	7.8	-0.2	-0.2	0.7	-0.1	0.2	-1.3	-2.8	-2.6
Deep venous thrombosis (DVT) (self-reported)	1.6	2.1	5.1	-2.0	-1.8	2.1	2.3	-0.3	0.0	0.0	0.1
Height	1.5	29.1	63.2	8.0	7.3	-4.5	-7.3	2.0	-3.4	-1.6	-5.0
Medication: Metformin	1.5	2.1	5.7	1.1	0.5	-1.5	-0.4	-0.1	-2.4	-1.5	-2.2
Asthma	1.5	3.0	8.0	2.0	2.0	-2.8	-1.3	1.3	1.7	1.1	0.5
Loud music exposure frequency	1.5	1.6	3.9	-1.3	-1.2	0.9	1.3	2.0	1.5	-0.7	-0.6
Had major operations	1.5	1.7	2.7	-1.4	-1.3	0.8	1.6	-0.7	-1.6	-1.5	-1.4
Illness, injury, bereavement, stress in last 2 years	1.5	1.8	3.5	1.7	1.5	-1.6	-1.9	-1.5	-0.8	-0.6	-0.4
Diabetes diagnosed by doctor	1.5	2.4	6.8	1.0	0.4	-1.0	-0.1	-2.2	-2.6	-1.2	-2.1
Supplements: Calcium	1.5	1.7	3.3	1.6	1.5	-1.3	-1.6	0.8	-0.5	-0.1	-1.8
Serious illness, injury or assault to yourself	1.4	1.7	4.1	-1.9	-2.0	1.2	1.8	0.7	0.0	-0.6	-0.4
Standing height	1.4	14.1	32.0	5.7	4.9	-3.1	-5.0	3.4	-1.5	-0.5	-2.8
Length of working week for main job	1.4	1.6	2.8	-1.4	-1.7	0.7	1.5	1.4	1.3	-0.8	1.0
Blood clot in the leg (DVT)	1.4	1.8	4.5	-1.8	-1.6	2.0	2.1	-0.1	0.0	-0.1	-0.0
Forced expiratory volume in 1-second (FEV1), predicted	1.4	2.9	5.8	2.4	2.0	-1.6	-2.4	1.8	-0.8	-0.4	-0.9
Risk taking	1.4	2.0	3.2	-1.3	-1.5	1.2	1.8	0.9	1.8	0.8	1.8
Diastolic blood pressure, automated reading	1.4	4.3	9.5	2.7	2.6	-3.1	-2.8	0.4	-1.4	0.4	-0.4
Heart attack/myocardial infarction (self-reported)	1.4	1.8	4.1	1.7	1.6	-1.5	-0.5	-1.1	-0.8	-0.4	-2.0
Lung FVC	1.3	6.7	12.4	-2.9	-2.7	3.5	3.2	1.7	2.8	1.5	1.6
Medication for hormone replacement therapy	1.3	1.4	3.7	1.0	1.3	-1.9	-0.9	0.7	-0.1	1.6	1.1
Heart attack	1.3	1.7	4.9	1.5	1.5	-1.2	-0.4	-1.1	-0.8	-0.5	-2.2
Medication: Ventolin 100micrograms inhaler	1.3	1.7	3.9	0.9	1.3	-1.4	-0.8	1.6	1.2	2.0	0.7
Comparative body size at age 10	1.3	3.5	13.4	0.6	1.0	-2.2	-0.8	-3.7	0.7	2.1	1.5
Age at first live birth	1.3	2.3	5.3	2.3	2.1	-1.8	-2.2	0.1	-0.2	-0.0	0.4
Handedness (chirality/laterality): Left-handed	1.3	1.6	4.8	0.9	1.1	-1.0	-0.9	-0.8	1.0	1.5	2.2
Asthma (self-reported)	1.3	2.6	6.5	1.9	1.9	-2.5	-1.1	1.7	1.8	0.4	0.2
Body Mass Index (BMI) (2010)	1.2	1.7	3.0	-1.7	-1.6	1.7	1.6	0.5	0.8	1.0	0.8
Ever had hysterectomy (womb removed)	1.2	1.4	4.9	-1.4	-1.3	2.2	1.3	0.4	0.5	0.1	0.5
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.2	3.5	-0.9	-1.2	1.9	1.1	0.6	0.2	1.4	0.8
Breast cancer (self-reported)	1.2	1.4	2.8	1.4	1.4	-1.7	-1.4	0.4	0.2	-1.4	-0.5
Age started oral contraceptive pill	1.2	1.5	2.9	1.5	1.6	-1.6	-1.7	0.2	-0.1	-1.1	-0.8
Schizophrenia vs Biploar Disorder	1.1	1.5	3.1	0.8	0.7	0.3	-1.3	-1.7	-1.0	-1.5	-1.7
Crohns Disease (2012)	1.1	1.8	3.9	-2.0	-1.9	0.5	1.5	-0.7	0.9	0.9	1.5
Type 2 Diabetes (T2D) (2018)	1.1	2.1	6.0	0.7	-0.2	-0.6	0.5	-1.2	-2.2	-1.9	-2.4
Chronotype (morning person)	1.1	2.6	5.2	1.7	1.9	-1.6	-2.3	-2.1	-0.4	-0.1	1.4
Number of treatments/medications taken	1.1	2.0	4.7	1.8	1.8	-2.2	-1.4	0.2	-1.0	-0.4	-1.3
Sensitivity / hurt feelings	1.1	1.9	4.2	-1.4	-1.7	-0.0	1.9	2.1	1.2	-0.8	0.2
Qualifications: CSEs or equivalent	1.1	1.5	3.9	1.0	0.8	-1.3	-0.7	2.0	-0.5	-1.8	-0.9
Diabetes (self-reported)	1.1	1.7	5.1	0.7	0.1	-0.7	0.0	-1.9	-2.3	-1.2	-1.5
Medication: Ramipril	1.1	1.5	5.5	1.4	1.0	-2.3	-0.6	-1.2	-0.4	1.0	0.5
Worrier / anxious feelings	1.1	2.0	3.6	1.5	1.3	-1.9	-1.3	1.1	-1.4	-1.6	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	5.4	-0.8	-0.5	0.6	0.6	1.4	-1.0	-2.3	-1.9
Number of children fathered	1.1	1.2	4.6	0.1	0.2	-0.6	-0.4	0.2	0.2	2.1	2.1
Alcohol intake frequency.	1.1	2.5	6.2	-2.5	-2.5	1.8	1.8	-0.2	0.7	-0.8	0.1
Age at last live birth	1.1	1.5	3.4	1.8	1.6	-0.9	-1.9	0.0	-1.4	0.3	-0.1
Supplements: Vitamin C	1.1	1.3	2.3	1.5	1.5	-1.3	-1.2	-0.2	-1.2	-0.2	-1.3
Osteoporosis (self-reported)	1.1	1.4	4.4	0.9	1.0	-0.7	-0.3	-1.8	1.2	2.1	0.2
Medication: Atorvastatin	1.1	1.4	5.3	-0.6	-0.2	0.1	0.3	-0.1	-1.8	-1.5	-2.3
Bipolar Disorder or Schizophrenia	1.0	2.5	7.7	-1.2	-1.3	2.8	1.1	-2.4	-1.1	1.0	0.3
Schizophrenia (2018)	1.0	2.0	9.0	-1.2	-1.2	3.0	1.3	-1.4	0.1	0.6	0.5
Alzheimer’s Disease (including proxy)	1.0	1.4	3.6	0.1	0.3	-0.4	-0.7	-1.9	1.4	1.4	1.7
LDL Cholesterol	1.0	1.6	3.9	-2.0	-1.8	1.7	1.4	0.4	0.5	-0.7	-0.4
Lupus	1.0	1.4	3.8	-0.8	-0.7	0.3	1.1	1.7	1.9	1.0	1.3
Rheumatoid Arthritis	1.0	1.3	3.5	-1.6	-1.3	1.9	1.1	0.7	0.7	0.2	0.8
Blood White Count	1.0	7.2	10.7	2.6	2.9	-2.2	-3.3	-0.1	-2.7	-3.0	-3.2
Relative age of first facial hair	1.0	2.1	4.1	1.4	1.3	-1.6	-1.5	0.9	-1.4	-1.2	-2.0
Leg fat-free mass (left)	1.0	5.5	24.0	-0.4	-0.2	0.4	0.7	-1.0	2.6	4.9	3.4
Leg predicted mass (left)	1.0	5.5	23.7	-0.5	-0.3	0.5	0.8	-1.0	2.5	4.9	3.4
Alcohol usually taken with meals	1.0	1.6	4.4	-1.4	-1.1	0.9	1.4	0.5	2.1	1.3	1.0
Medication: Lansoprazole	1.0	1.1	5.9	0.7	0.8	-0.7	-1.0	-2.4	-0.8	-0.2	0.3
Ever highly irritable/argumentative for 2 days	1.0	1.2	3.4	0.7	0.6	-0.1	-0.9	0.4	-1.9	-1.3	-1.7
Exposure to tobacco smoke outside home	1.0	1.3	4.8	-0.8	-1.0	0.6	0.8	2.2	1.6	0.1	0.6
Medication: Seretide 50 evohaler	1.0	1.2	3.0	1.1	1.0	-1.6	-1.0	1.7	0.8	0.3	-0.5
Leg pain on walking	1.0	1.2	3.2	-1.8	-1.8	0.9	1.4	-0.7	0.4	-0.2	-0.2
Leg fat-free mass (right)	1.0	5.3	23.6	-0.2	-0.1	0.3	0.5	-1.4	2.3	4.9	3.3
Leg predicted mass (right)	1.0	5.2	23.5	-0.2	-0.1	0.2	0.4	-1.4	2.2	4.8	3.3
Intelligence (Savage-Jansen 2018)	0.9	2.7	5.5	-1.5	-1.6	1.0	1.6	-1.5	1.7	1.6	2.4
Verbal and Numeric Reasoning (VNR)	0.9	2.3	5.1	-1.5	-1.7	2.2	1.2	-2.1	0.6	0.7	1.2
Ever used hormone-replacement therapy (HRT)	0.9	1.2	3.0	0.3	0.2	-1.7	0.2	1.3	-1.2	-1.0	-1.5
Diabetes (mother)	0.9	1.1	2.9	-0.5	-0.8	0.5	0.7	-0.8	-1.7	-1.4	-1.3
Arm fat percentage (right)	0.9	3.5	9.4	-3.1	-2.6	2.1	2.5	-0.0	0.3	0.5	1.0
Alcohol intake versus 10 years previously	0.9	1.4	2.6	-1.3	-1.4	-0.2	1.6	1.2	1.6	0.6	0.9
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.4	3.5	-1.2	-1.2	-0.5	1.2	1.9	-0.2	-1.6	-0.8
Noisy workplace	0.9	1.1	4.5	-0.3	-0.1	0.3	-0.4	2.1	1.1	-1.5	-0.4
Lung cancer (father)	0.9	1.1	3.0	-0.9	-1.0	0.9	0.9	-1.2	0.1	0.8	1.7
Health satisfaction	0.9	1.1	3.9	-1.0	-0.8	0.6	0.6	2.0	-0.5	-1.5	-0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.1	1.7	-1.3	-1.0	1.1	1.0	-1.1	-1.3	1.0	0.1
Mood swings	0.9	1.6	4.3	-1.7	-1.8	1.1	2.1	-0.5	-0.3	-0.1	0.8
Osteoarthritis (self-reported)	0.9	1.1	5.8	0.2	0.3	-0.2	-0.9	-0.5	-2.4	-1.0	-0.9
Pain type(s) experienced in last month: Hip pain	0.9	1.2	5.1	0.3	0.2	0.1	0.1	0.3	-1.0	-1.7	-2.3
Crohns Disease (2017)	0.8	1.8	8.9	-1.4	-1.3	0.3	0.8	-3.0	-0.3	0.8	0.8
Fasting Glucose	0.8	1.0	3.2	-1.1	-1.8	0.0	1.1	-1.2	-0.8	-0.5	0.5
Schizophrenia (2014)	0.8	1.7	6.7	-0.7	-0.8	2.2	0.8	-2.6	0.0	0.6	0.1
Waist Hip Ratio (WHR)	0.8	3.6	6.8	-1.6	-1.7	2.6	1.4	0.5	-1.4	-2.4	-2.6
Hypothyroidism (self reported)	0.8	1.8	3.5	1.2	1.6	-1.9	-1.6	-1.9	-0.7	-0.3	0.1
Diabetes (father)	0.8	1.0	2.2	-1.1	-1.5	0.2	1.3	-0.6	1.5	-0.4	0.3
Average weekly fortified wine intake	0.8	0.9	4.6	-0.6	-1.0	0.6	0.7	0.7	2.1	0.1	-0.1
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	1.9	0.5	0.8	-1.2	-0.6	1.4	1.0	0.0	1.2
Qualifications: None of the above	0.8	1.7	4.7	-1.7	-1.7	1.2	2.2	-1.0	0.5	0.1	-0.5
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	3.6	1.5	1.5	-0.4	-1.9	-0.7	-0.7	-0.7	-0.2
Leg fat percentage (right)	0.8	2.8	6.2	-2.5	-2.3	2.1	2.3	0.4	-0.3	-1.0	-0.8
Shortness of breath walking on level ground	0.8	0.9	4.5	-0.6	-0.4	-0.3	0.7	1.1	-0.4	-0.7	-2.1
Neck or shoulder pain in last month	0.8	1.2	3.0	0.6	0.6	-1.4	-0.5	0.5	-0.8	-1.6	-1.7
Leg fat mass (right)	0.8	3.0	6.2	-2.5	-2.2	2.3	2.4	0.0	0.8	0.9	0.8
Whole body fat-free mass	0.8	4.4	21.0	0.5	0.4	-0.1	0.0	-0.7	2.2	4.6	2.9
Arm fat percentage (left)	0.8	3.2	8.6	-2.9	-2.5	2.0	2.3	-0.4	0.3	0.4	0.9
Commuting to job workplace: Walk	0.8	0.8	1.4	0.8	1.1	-1.0	-1.2	-0.2	-0.7	-1.0	-0.8
Whole body water mass	0.8	4.6	21.6	0.5	0.4	-0.2	0.1	-0.7	2.4	4.7	3.0
Hearing aid user	0.8	0.9	3.2	-1.1	-0.9	0.4	0.7	1.8	0.4	-0.9	0.6
Financial situation satisfaction	0.8	1.0	3.6	0.7	0.5	-0.7	-0.8	1.9	0.4	-1.5	0.1
Leg fat percentage (left)	0.8	2.8	6.4	-2.5	-2.3	2.1	2.1	-0.0	-0.6	-1.0	-0.7
Irritability	0.8	1.3	3.4	-1.1	-1.2	1.4	1.8	1.5	-0.3	-0.3	-0.2
Basal cell carcinoma (self-reported)	0.8	0.9	3.2	-0.8	-0.7	-0.0	0.7	0.2	1.5	0.6	1.8
Bipolar Disorder (2018)	0.7	1.1	4.1	-0.3	-0.5	0.7	0.1	-2.0	-1.9	0.8	-0.1
Ovarian Cancer	0.7	0.9	1.9	1.0	1.1	-1.4	-1.2	-0.5	0.3	-1.3	0.0
HDL Cholesterol	0.7	1.2	5.6	0.2	0.3	-0.4	-0.4	-1.5	-0.0	1.1	2.4
Neuroticism (2016)	0.7	1.1	6.3	-0.2	0.4	-0.3	-0.2	-1.3	-0.3	0.5	2.5
Medication: Co-codamol	0.7	0.8	4.6	0.0	0.1	-0.8	-0.1	2.1	-0.3	-0.8	-0.8
Severe depression (siblings)	0.7	0.8	1.8	0.6	0.9	0.8	-1.2	0.5	-1.4	0.8	0.8
Townsend deprivation index at recruitment	0.7	0.9	2.7	-0.1	0.0	0.6	0.0	1.4	-0.4	-1.6	-1.5
Trunk fat-free mass	0.7	3.9	18.2	0.9	0.7	-0.3	-0.2	-0.2	2.1	4.3	2.6
Arm fat mass (right)	0.7	3.1	6.4	-2.5	-2.1	1.8	2.3	-0.1	0.9	1.5	1.5
Trunk predicted mass	0.7	3.8	17.7	0.8	0.7	-0.2	-0.2	-0.2	2.1	4.2	2.6
Illnesses of siblings: Diabetes	0.7	0.9	1.9	-0.8	-1.0	0.2	1.3	-0.8	0.2	1.2	1.4
Arm fat mass (left)	0.7	2.9	5.9	-2.4	-2.0	1.8	2.1	-0.4	0.9	1.5	1.4
Medication: Lisinopril	0.7	1.0	2.1	1.4	1.1	-0.3	-1.1	-1.4	-1.0	0.0	-0.4
Basal metabolic rate	0.7	3.7	17.6	0.1	0.1	0.2	0.4	-0.5	2.0	4.2	2.6
Number of operations (self-reported)	0.7	1.0	2.3	-1.3	-1.2	0.5	1.5	0.5	0.7	1.0	0.9
Alcohol drinker status: Previous	0.7	0.8	3.4	-0.0	-0.3	-1.1	-0.1	1.8	0.7	-1.2	0.2
Leg fat mass (left)	0.7	2.9	6.2	-2.5	-2.2	2.2	2.3	-0.2	0.6	0.9	0.7
Prostate Cancer	0.6	0.9	2.8	-0.0	-0.1	-0.6	0.3	1.7	0.1	-1.1	-1.5
Mean Putamen Volume	0.6	0.7	2.2	-0.5	-0.3	0.8	0.2	-0.4	-1.3	1.5	0.7
Respiratory disease	0.6	1.3	3.9	1.3	1.4	-2.0	-1.0	0.5	1.2	0.8	0.3
Supplements: Zinc	0.6	0.7	1.3	0.9	0.9	-0.3	-1.2	-0.6	-0.9	1.0	-0.1
Pack years adult smoking proportion	0.6	0.9	2.1	-0.5	-0.8	1.2	0.8	1.5	-0.6	-0.4	-1.3
Current tobacco smoking	0.6	0.9	3.5	-0.4	-0.6	1.2	0.8	1.9	0.9	0.6	0.3
Sitting height	0.6	4.2	11.4	-0.7	-1.0	1.8	1.0	3.4	2.6	2.9	1.1
Waist circumference	0.6	2.1	5.8	-1.9	-1.5	2.4	1.6	-0.9	0.1	1.1	0.6
Mouth/teeth dental problems	0.6	1.0	2.7	0.8	1.1	-0.4	-1.3	-1.0	-1.6	-0.8	-0.5
Fluid intelligence score	0.6	1.2	3.5	-0.5	-1.0	1.1	0.5	-1.9	0.7	1.3	1.0
Gout (self-reported)	0.6	0.8	1.8	-0.6	-0.7	0.8	0.9	-0.9	1.3	0.3	1.1
Wheeze or whistling in the chest in last year	0.6	1.0	3.6	-0.4	-0.1	-0.6	0.4	1.2	1.9	1.2	0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	3.6	-0.0	0.1	0.1	0.8	1.9	0.7	-0.4	-1.0
Number of self-reported non-cancer illnesses	0.6	1.1	2.7	1.4	1.1	-1.6	-0.7	-0.1	0.3	0.7	-1.4
Average weekly champagne plus white wine intake	0.6	0.8	1.8	1.1	1.3	-1.2	-1.1	-0.4	-0.1	0.4	-0.4
Alcohol drinker status: Never	0.6	0.7	2.4	-0.8	-0.5	0.7	0.6	-0.4	1.6	0.7	0.9
Commuting to job workplace: Cycle	0.6	0.8	3.5	0.4	0.1	0.1	-0.0	-0.1	-1.9	-0.5	-1.4
Myopia	0.6	0.8	3.6	-0.2	-0.5	1.5	0.3	-0.3	-0.4	0.2	-1.9
Depression (Nagel 2018)	0.5	0.8	2.8	0.2	0.5	-0.9	-0.2	-1.4	-1.7	-0.4	0.2
Alzheimer’s Disease (in mother)	0.5	0.6	1.1	0.7	0.9	-0.9	-0.8	-0.5	0.6	0.8	1.1
Bipolar Disorder (2011)	0.5	0.5	1.9	-0.2	-0.1	-0.7	0.3	0.6	1.0	1.4	0.0
Frequency of depressed mood in last 2 weeks	0.5	0.6	2.0	-0.5	-0.4	-0.2	0.7	-0.6	-1.4	-1.3	-0.4
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.6	-0.7	-0.9	0.4	1.3	0.4	0.5	1.2	0.3
Age when periods started (menarche)	0.5	1.1	4.8	-0.9	-0.8	1.2	0.7	-2.2	-0.7	0.2	-0.5
Medication: Levothyroxine sodium	0.5	0.9	1.5	0.8	0.9	-1.1	-1.2	-1.2	-1.1	-0.8	-0.3
Had other major operations	0.5	0.6	2.4	-0.6	-0.7	0.1	0.4	1.6	0.1	1.0	0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.0	2.3	-1.4	-1.5	0.5	1.5	-0.3	-1.1	-0.2	0.4
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	2.1	-0.4	-0.3	0.9	0.3	-0.3	0.8	1.3	1.4
Time employed in main current job	0.5	0.6	1.6	-0.2	0.2	1.3	-0.1	0.5	-1.2	-0.4	-0.9
Falls in the last year	0.5	0.6	3.7	0.2	0.2	0.2	-0.5	-1.9	-0.8	-0.4	-0.4
Number of live births	0.5	0.7	2.4	-1.6	-1.3	0.5	0.7	0.2	-0.1	-0.1	0.7
Qualifications: A levels/AS levels or equivalent	0.5	1.1	2.7	1.1	0.6	-0.3	-0.9	0.4	1.6	1.1	1.6
Tense / ‘highly strung’	0.5	0.8	4.0	-0.4	-0.5	0.7	1.0	2.0	-0.1	-0.3	-0.4
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	1.9	0.8	0.9	-1.2	-1.3	-1.4	-0.5	-0.7	0.2
Arm fat-free mass (right)	0.5	2.7	12.9	0.8	0.7	-0.3	-0.2	-1.0	1.6	3.6	1.9
Qualifications: College or University degree	0.5	1.5	4.2	0.7	0.3	-0.9	-0.5	-0.7	1.5	1.8	2.1
Medication: Omeprazole	0.5	0.6	1.4	-0.6	-0.7	0.9	1.2	-1.0	-0.8	-0.2	-0.7
Arm predicted mass (right)	0.5	2.7	13.0	0.9	0.8	-0.2	-0.3	-0.8	1.7	3.6	1.8
Overall health rating	0.5	1.2	2.5	-0.6	-0.8	1.2	0.9	0.6	-1.1	-1.6	-1.4
Chest pain or discomfort	0.5	0.7	3.1	0.8	0.6	-0.5	-0.2	-1.1	-0.3	-0.2	-1.8
Arm fat-free mass (left)	0.5	2.5	12.0	0.5	0.5	-0.1	0.1	-0.4	1.7	3.5	2.0
Arm predicted mass (left)	0.5	2.4	11.8	0.3	0.3	0.1	0.2	-0.4	1.7	3.4	2.0
Depressed Affect (Nagel 2018)	0.4	0.8	1.6	-1.2	-1.2	-0.1	1.1	0.3	-0.9	-0.7	0.6
Age at First Birth	0.4	0.6	1.3	1.1	1.2	-0.7	-1.1	0.5	-0.4	0.0	0.5
Heel T-Score	0.4	3.0	8.0	-2.5	-2.8	1.3	2.1	0.8	-1.4	-0.2	-0.8
Vitamin and mineral supplements	0.4	0.6	1.4	-0.8	-1.0	1.2	1.0	0.7	0.4	0.0	-0.1
Fed-up feelings	0.4	0.7	1.4	-1.1	-1.1	0.7	1.2	0.1	-0.6	-0.7	0.1
Relative age voice broke	0.4	0.6	1.3	-0.4	-0.7	0.7	1.1	0.6	0.8	1.0	0.8
Had menopause	0.4	0.6	2.5	0.4	0.3	-1.2	-0.3	1.6	-0.0	0.1	-0.6
Financial difficulties in last 2 years	0.4	0.6	1.3	-0.7	-0.5	-0.1	1.0	0.9	0.7	-0.1	1.1
Happiness	0.4	0.4	1.0	1.0	0.4	-0.8	-0.6	0.6	-0.4	-0.7	-0.5
Prospective memory result	0.4	0.4	1.0	-0.7	-0.4	0.6	0.9	0.5	-0.4	-1.0	-0.5
Forced vital capacity (FVC), Best measure	0.4	1.3	5.2	1.5	1.0	0.2	-1.0	2.3	0.2	0.2	-1.1
Body fat percentage	0.4	1.5	3.1	-1.8	-1.5	1.4	1.3	0.0	-1.0	-1.2	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.0	-0.5	-0.3	1.0	0.5	-1.0	-1.0	-0.5	-0.5
Family relationship satisfaction	0.4	0.5	1.5	-0.1	-0.5	-0.0	0.2	0.9	-0.5	-1.2	-0.9
Average weekly red wine intake	0.4	0.6	1.9	0.2	0.4	0.1	0.3	1.4	1.3	0.3	0.7
Loneliness, isolation	0.4	0.5	1.2	-0.7	-1.1	-0.8	0.7	0.8	-0.5	-0.6	0.0
Qualifications: nursing, teaching	0.4	0.6	1.4	1.2	0.7	-0.7	-0.8	0.4	0.7	-0.1	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.1	-0.5	-0.6	0.5	0.6	0.7	-0.7	-0.9	-1.1
Medication: Gliclazide	0.4	0.4	1.8	-0.2	-0.6	-0.1	0.5	-0.6	-1.3	-0.3	-0.6
Mother’s age at death	0.4	0.5	1.0	-0.5	-0.7	0.2	0.5	-0.8	-1.0	0.8	0.8
Commuting to job workplace: Public transport	0.4	0.5	2.3	0.4	0.2	-0.7	-0.8	0.0	-0.8	0.1	1.5
Pack years of smoking	0.4	0.6	1.2	-0.6	-0.9	0.9	0.8	1.1	-0.4	-0.1	-1.0
Breast Cancer	0.3	0.8	1.9	1.1	1.4	-0.4	-0.9	1.3	0.2	-0.5	-0.7
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.3	0.2	0.2	-0.7	0.4	-0.9	0.2	1.1	0.2
Trunk fat percentage	0.3	1.3	1.8	-1.4	-1.1	1.2	0.8	0.1	-1.3	-1.3	-1.3
Taking other prescription medications	0.3	0.5	1.4	0.0	0.0	-1.0	-0.1	-0.1	-0.1	-1.2	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.8	-1.1	-1.0	0.5	1.3	0.1	-1.4	-0.4	0.1
Forced vital capacity (FVC)	0.3	1.1	4.4	1.2	0.8	0.1	-0.8	2.1	0.3	0.2	-1.1
Weight	0.3	1.4	6.6	-0.7	-0.5	0.8	0.7	-0.3	0.8	2.6	1.3
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.1	0.1	0.2	0.3	0.2	1.0	0.7	0.8	0.5
Mouth/teeth dental problems: Dentures	0.3	0.5	1.5	-0.8	-1.0	-0.4	1.2	0.6	0.3	-0.4	-0.1
Breastfed as a baby	0.3	0.4	1.1	0.0	0.1	0.2	0.3	-0.8	-0.9	-0.8	-1.0
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.0	0.7	0.8	-0.0	-0.4	-1.0	-0.4	0.8	-0.1
Pulse rate, automated reading	0.3	1.1	4.2	0.3	0.4	-0.2	-0.6	1.8	-0.0	-2.0	-0.9
Long-standing illness, disability or infirmity	0.3	0.4	1.7	0.6	0.6	-0.9	0.0	-0.4	-0.3	-0.5	-1.3
Ever had bowel cancer screening	0.3	0.4	1.7	-0.3	-0.2	-0.3	-0.4	0.3	-0.3	1.3	0.9
Smoking status: Current	0.3	0.4	2.2	0.1	-0.1	0.8	0.4	1.5	0.3	0.5	-0.2
Guilty feelings	0.3	0.5	1.6	0.2	0.3	-0.8	-0.6	-0.8	-0.2	-0.5	1.3
Ever taken oral contraceptive pill	0.3	0.3	1.0	-0.6	-0.8	0.2	0.2	1.0	0.6	0.3	0.4
Ever depressed for a whole week	0.3	0.3	0.8	0.1	0.2	-0.6	0.2	0.7	-0.5	-0.9	-0.8
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.5	0.5	0.3	-0.0	0.3	-0.7	-1.2	-0.3	-0.8
Worry (Nagel 2018)	0.2	0.5	1.4	0.6	0.8	-0.8	-0.7	1.2	-0.6	-0.2	-0.1
Alzheimer’s Disease (in father)	0.2	0.3	0.7	0.4	0.4	-0.5	-0.7	-0.8	-0.2	0.4	-0.2
Major Depression (MDD)	0.2	0.3	1.6	0.2	0.2	0.4	-0.2	-1.3	0.2	0.5	0.0
Reaction Time	0.2	0.4	1.5	0.2	0.2	-0.8	0.1	-0.0	-0.9	-1.2	-0.7
Triglycerides	0.2	0.3	0.8	-0.8	-0.9	0.3	0.4	0.1	-0.1	-0.3	-0.7
Blood Eosinophil Count	0.2	1.6	3.9	-0.5	-0.5	-0.0	0.3	-1.8	1.7	1.5	2.0
Smoking Status	0.2	0.5	2.5	0.2	0.1	1.0	0.1	1.6	0.3	0.4	-0.3
Neuroticism	0.2	0.5	1.2	-0.8	-0.8	-0.3	1.1	0.6	-0.2	-0.1	1.1
Hearing difficulty/problems: Yes	0.2	0.3	0.8	-0.6	-0.4	0.2	0.3	0.9	-0.7	-0.6	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.6	-0.6	-0.5	0.5	0.8	-0.6	-0.3	0.1	0.4
Multivitamins +/- minerals	0.2	0.3	0.5	0.1	0.4	-0.7	-0.5	-0.7	0.3	-0.7	0.4
Stomach or abdominal pain in last month	0.2	0.2	0.6	0.2	0.4	-0.8	0.0	0.6	-0.6	0.5	0.5
Past tobacco smoking	0.2	0.5	1.5	-0.7	-0.7	0.2	0.1	-0.9	0.6	0.3	1.2
Neuroticism score	0.2	0.3	0.6	-0.5	-0.5	0.1	0.8	0.5	-0.7	-0.7	0.4
Hip circumference	0.2	0.8	2.8	-0.6	-0.3	0.3	0.4	0.3	0.9	1.7	1.2
Father’s age at death	0.2	0.2	1.1	-0.0	-0.4	0.1	0.2	-0.5	0.3	1.1	0.6
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.9	0.7	0.2	-0.7	-0.1	0.0	0.9	0.4	-0.1
Number of full brothers	0.2	0.3	0.5	-0.2	-0.1	0.2	0.6	0.6	-0.7	-0.6	-0.7
Worry too long after embarrassment	0.2	0.3	1.1	0.5	0.3	-1.1	-0.3	0.3	-0.8	-0.6	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	0.6	-0.5	-0.4	0.4	0.5	-0.3	0.5	0.1	0.8
Mean time to correctly identify matches	0.2	0.3	0.8	0.3	0.1	-0.9	-0.3	-0.8	-0.6	-0.3	-0.8
Whole body fat mass	0.2	1.0	2.5	-1.6	-1.3	1.3	1.3	-0.1	0.0	0.4	0.1
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.9	-0.4	-0.5	0.1	0.9	0.1	0.1	0.5	0.3
Smoking status: Previous	0.2	0.4	1.2	-0.0	0.0	0.4	0.4	1.1	-0.7	-0.3	-1.0
Friendships satisfaction	0.2	0.2	0.5	-0.1	-0.5	-0.5	0.6	0.6	-0.2	-0.2	0.7
Ever smoked	0.2	0.3	0.8	0.5	0.3	-0.4	0.1	0.9	0.6	-0.5	-0.6
Average weekly beer plus cider intake	0.2	0.3	1.5	0.4	0.7	0.1	-0.5	1.2	0.1	0.4	-0.1
Neuroticism (Nagel 2018)	0.1	0.3	1.0	-0.4	-0.2	-0.6	0.2	0.9	-1.0	-0.4	0.1
Blood Red Count	0.1	0.9	3.5	0.8	0.7	-1.9	-0.4	-0.9	0.3	-0.0	-1.3
Tanning	0.1	1.5	3.0	-1.2	-0.9	1.2	1.7	0.6	1.7	1.0	0.8
Maternal smoking around birth	0.1	0.2	0.8	-0.1	-0.3	0.3	0.3	-0.6	-0.9	0.3	-0.2
Trunk fat mass	0.1	0.5	1.4	-1.1	-0.9	1.2	0.7	0.0	-0.5	0.1	-0.4
Nervous feelings	0.1	0.2	0.9	0.2	0.4	0.8	-0.4	-0.2	-1.0	0.1	0.3
Hearing difficulty/problems with background noise	0.1	0.2	0.7	-0.4	-0.2	-0.3	-0.0	-0.9	-0.3	-0.1	0.6
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.2	-0.1	-0.1	-0.3	0.4	0.5	-0.2	0.2	-0.3
Depression (self-reported)	0.1	0.1	0.4	-0.6	0.1	0.5	-0.0	-0.3	-0.1	-0.1	-0.3
Medication: Allopurinol	0.1	0.2	0.4	-0.2	-0.5	0.1	0.6	-0.4	0.2	-0.5	0.2
Suffer from ‘nerves’	0.1	0.2	0.3	-0.5	-0.2	0.4	0.3	-0.1	-0.6	0.4	0.5
Knee pain experienced in last month	0.1	0.1	0.3	-0.5	-0.3	-0.2	-0.0	-0.5	0.1	-0.0	-0.3
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.5	0.4	0.4	-0.6	-0.5	-0.3	-0.2	-0.1	0.7
Miserableness	0.1	0.2	0.4	-0.4	-0.4	0.2	0.6	0.6	-0.4	-0.1	0.7
Wears glasses or contact lenses	0.1	0.1	0.4	-0.2	-0.2	0.6	0.2	0.4	-0.0	0.6	-0.2
Hair Pigment	0.0	1.2	2.5	1.6	1.6	-0.4	-1.3	0.3	-0.4	-1.1	-0.9
Hair/balding pattern: Pattern 3	0.0	0.1	0.2	-0.0	-0.0	0.5	0.3	0.2	0.0	-0.1	-0.3

Hub : Genes

BCAR1

Models

Trait associations