[Hub]/) : Traits : Impedance of leg (left) : ← →

chr1:226,385,623-228,663,659

Best TWAS P=1.12e-09 · Best GWAS P=1.08e-10 conditioned to 0.406

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	The Cancer Genome Atlas	Colon Adenocarcinoma	PSEN2	0.14	0.06	lasso	4	0.07	5.4e-05	-5.8	6.1	1.1e-09	-0.42	0.00	1.00	TRUE
15	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	SNAP47	0.07	0.05	blup	54	0.05	2.9e-03	-5.2	5.9	3.9e-09	-0.31	0.01	0.67	TRUE
9	NTR	Blood	ADCK3	0.06	0.08	enet	9	0.08	2.5e-23	5.5	5.3	9.2e-08	-0.45	0.49	0.51	TRUE
2	GTEx	Adipose Subcutaneous	CDC42BPA	0.10	0.05	lasso	5	0.02	3.6e-03	4.7	-5.9	4.4e-09	0.65	0.35	0.58	FALSE
3	GTEx	Brain Cortex	SNAP47	0.21	0.05	lasso	9	0.04	2.2e-02	-5.2	5.9	4.4e-09	-0.34	0.06	0.55	FALSE
1	CommonMind	Brain Pre-frontal Cortex	SNAP47	0.23	0.19	lasso	7	0.19	5.7e-23	-5.4	5.8	7.8e-09	-0.33	0.02	0.98	FALSE
12	The Cancer Genome Atlas	Colon Adenocarcinoma	SNAP47	0.05	0.05	lasso	3	0.06	2.4e-04	-5.2	5.8	8.7e-09	-0.34	0.01	0.90	FALSE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	SNAP47	0.08	0.06	blup	54	0.08	1.2e-09	-5.2	5.7	1.6e-08	-0.34	0.01	0.99	FALSE
16	The Cancer Genome Atlas	Lung Adenocarcinoma	SNAP47	0.03	0.02	enet	4	0.02	1.5e-03	-5.3	5.5	4.0e-08	-0.27	0.01	0.97	FALSE
7	GTEx	Muscle Skeletal	SNAP47	0.09	0.08	lasso	10	0.08	7.7e-08	-5.4	5.5	4.8e-08	-0.30	0.02	0.98	FALSE
10	YFS	Blood	JMJD4	0.11	0.12	lasso	4	0.12	3.7e-36	-5.2	-5.4	5.8e-08	0.35	0.02	0.98	FALSE
6	GTEx	Esophagus Muscularis	ADCK3	0.07	0.02	lasso	5	0.01	4.1e-02	3.9	-5.4	6.8e-08	0.49	0.09	0.67	FALSE
8	GTEx	Testis	SNAP47	0.23	0.21	enet	15	0.21	7.5e-10	-5.3	5.4	7.5e-08	-0.26	0.03	0.96	FALSE
13	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PSEN2	0.02	0.02	blup	51	0.02	1.6e-03	-4.3	5.3	1.1e-07	-0.39	0.02	0.72	FALSE
5	GTEx	Esophagus Gastroesophageal Junction	ADCK3	0.23	0.12	lasso	9	0.09	3.6e-04	-4.2	-5.3	1.3e-07	0.35	0.46	0.05	FALSE
17	The Cancer Genome Atlas	Prostate Adenocarcinoma	CABC1	0.08	0.02	enet	6	0.05	6.6e-06	-5.8	-5.2	1.7e-07	0.54	0.23	0.65	FALSE
4	GTEx	Cells Transformed fibroblasts	SNAP47	0.17	0.12	enet	18	0.12	1.9e-09	-5.2	5.2	2.6e-07	-0.24	0.04	0.96	FALSE