[Hub]/) : Traits : Impedance of leg (left) :

chr1:226,385,623-228,663,659

Best TWAS P=1.12e-09 · Best GWAS P=1.08e-10 conditioned to 0.406

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SNAP47 0.23 0.19 lasso 7 0.19 5.7e-23 -5.4 5.8 7.8e-09 -0.33 0.02 0.98 FALSE
2 GTEx Adipose Subcutaneous CDC42BPA 0.10 0.05 lasso 5 0.02 3.6e-03 4.7 -5.9 4.4e-09 0.65 0.35 0.58 FALSE
3 GTEx Brain Cortex SNAP47 0.21 0.05 lasso 9 0.04 2.2e-02 -5.2 5.9 4.4e-09 -0.34 0.06 0.55 FALSE
4 GTEx Cells Transformed fibroblasts SNAP47 0.17 0.12 enet 18 0.12 1.9e-09 -5.2 5.2 2.6e-07 -0.24 0.04 0.96 FALSE
5 GTEx Esophagus Gastroesophageal Junction ADCK3 0.23 0.12 lasso 9 0.09 3.6e-04 -4.2 -5.3 1.3e-07 0.35 0.46 0.05 FALSE
6 GTEx Esophagus Muscularis ADCK3 0.07 0.02 lasso 5 0.01 4.1e-02 3.9 -5.4 6.8e-08 0.49 0.09 0.67 FALSE
7 GTEx Muscle Skeletal SNAP47 0.09 0.08 lasso 10 0.08 7.7e-08 -5.4 5.5 4.8e-08 -0.30 0.02 0.98 FALSE
8 GTEx Testis SNAP47 0.23 0.21 enet 15 0.21 7.5e-10 -5.3 5.4 7.5e-08 -0.26 0.03 0.96 FALSE
9 NTR Blood ADCK3 0.06 0.08 enet 9 0.08 2.5e-23 5.5 5.3 9.2e-08 -0.45 0.49 0.51 TRUE
10 YFS Blood JMJD4 0.11 0.12 lasso 4 0.12 3.7e-36 -5.2 -5.4 5.8e-08 0.35 0.02 0.98 FALSE
11 The Cancer Genome Atlas Colon Adenocarcinoma PSEN2 0.14 0.06 lasso 4 0.07 5.4e-05 -5.8 6.1 1.1e-09 -0.42 0.00 1.00 TRUE
12 The Cancer Genome Atlas Colon Adenocarcinoma SNAP47 0.05 0.05 lasso 3 0.06 2.4e-04 -5.2 5.8 8.7e-09 -0.34 0.01 0.90 FALSE
13 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PSEN2 0.02 0.02 blup 51 0.02 1.6e-03 -4.3 5.3 1.1e-07 -0.39 0.02 0.72 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma SNAP47 0.08 0.06 blup 54 0.08 1.2e-09 -5.2 5.7 1.6e-08 -0.34 0.01 0.99 FALSE
15 The Cancer Genome Atlas Liver Hepatocellular Carcinoma SNAP47 0.07 0.05 blup 54 0.05 2.9e-03 -5.2 5.9 3.9e-09 -0.31 0.01 0.67 TRUE
16 The Cancer Genome Atlas Lung Adenocarcinoma SNAP47 0.03 0.02 enet 4 0.02 1.5e-03 -5.3 5.5 4.0e-08 -0.27 0.01 0.97 FALSE
17 The Cancer Genome Atlas Prostate Adenocarcinoma CABC1 0.08 0.02 enet 6 0.05 6.6e-06 -5.8 -5.2 1.7e-07 0.54 0.23 0.65 FALSE