Best TWAS P=5.17e-10 · Best GWAS P=1.94e-09 conditioned to 0.00895
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | WDR75 | 0.05 | 0.04 | lasso | 2 | 0.03 | 0.0012 | -5.7 | 5.8 | 5.9e-09 | -0.85 | 0.04 | 0.87 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Male) | WDR75 | 0.16 | 0.00 | lasso | 9 | 0.00 | 0.2640 | -5.5 | 5.4 | 8.1e-08 | -0.72 | 0.04 | 0.29 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | WDR75 | 0.05 | 0.04 | lasso | 4 | 0.03 | 0.0012 | -5.5 | 5.6 | 2.6e-08 | -0.89 | 0.05 | 0.93 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | COL5A2 | 0.04 | 0.00 | blup | 79 | 0.02 | 0.0059 | -5.4 | 6.2 | 5.2e-10 | -0.65 | 0.03 | 0.54 | TRUE |