TWAS
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Usage
Models
Genes
Traits
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Traits
:
Impedance of leg (left)
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chr2:206,440,641-207,874,372
Best TWAS P=3.57e-08 · Best GWAS P=3.1e-09 conditioned to 0.00241
206.4M
206.6M
206.8M
207M
207.2M
207.4M
207.6M
207.8M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
METSIM
Adipose
ZDBF2
0.03
0.00
bslmm
436
0.00
0.113
-5.3
5.5
3.6e-08
-0.66
0.10
0.82
TRUE
1
GTEx
Artery Tibial
ZDBF2
0.07
0.02
lasso
5
0.02
0.021
5.2
5.3
1.5e-07
-0.66
0.11
0.84
FALSE