Best TWAS P=1.46e-09 · Best GWAS P=6.03e-12 conditioned to 0.000859
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | CCNL1 | 0.03 | 0.01 | blup | 432 | 0.02 | 9.6e-04 | -5.1 | -6.0 | 1.5e-09 | 0.83 | 0.04 | 0.95 | TRUE |
| 2 | YFS | Blood | CCNL1 | 0.09 | 0.16 | bslmm | 434 | 0.17 | 3.0e-52 | -5.8 | -5.8 | 8.6e-09 | 0.79 | 0.85 | 0.15 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | CCNL1 | 0.06 | 0.02 | lasso | 3 | 0.04 | 6.9e-05 | -6.8 | 5.8 | 6.0e-09 | -0.85 | 0.00 | 0.99 | FALSE |