Best TWAS P=7.54e-10 · Best GWAS P=2.17e-10 conditioned to 0.00338
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | TRAPPC3 | 0.10 | 0.08 | lasso | 3 | 0.08 | 7.2e-07 | 5.1 | -5.4 | 6.0e-08 | -0.76 | 0.20 | 0.77 | FALSE |
| 2 | GTEx | Whole Blood | MAP7D1 | 0.12 | 0.09 | lasso | 3 | 0.09 | 8.3e-09 | 5.4 | 5.6 | 2.5e-08 | 0.78 | 0.32 | 0.68 | FALSE |
| 3 | NTR | Blood | MAP7D1 | 0.02 | 0.03 | lasso | 3 | 0.02 | 3.4e-08 | 5.1 | 5.3 | 1.4e-07 | 0.76 | 0.22 | 0.78 | FALSE |
| 4 | YFS | Blood | MAP7D1 | 0.04 | 0.03 | lasso | 7 | 0.03 | 8.3e-10 | 5.1 | 5.4 | 7.2e-08 | 0.78 | 0.54 | 0.46 | FALSE |
| 5 | The Cancer Genome Atlas | Colon Adenocarcinoma | MAP7D1 | 0.06 | 0.01 | blup | 33 | 0.04 | 1.3e-03 | 5.3 | 5.8 | 6.3e-09 | 0.75 | 0.02 | 0.46 | FALSE |
| 6 | The Cancer Genome Atlas | Colon Adenocarcinoma | TRAPPC3 | 0.07 | 0.02 | blup | 38 | 0.03 | 5.7e-03 | 5.6 | 6.2 | 7.5e-10 | 0.69 | 0.04 | 0.53 | TRUE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | COL8A2 | 0.04 | 0.03 | blup | 30 | 0.03 | 2.6e-04 | 5.1 | -5.5 | 3.3e-08 | -0.54 | 0.01 | 0.95 | FALSE |