Best TWAS P=1.23e-07 · Best GWAS P=5.7e-08 conditioned to 0.0512
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | TRIM4 | 0.18 | 0.09 | enet | 17 | 0.13 | 1.8e-07 | -4.7 | 5.3 | 1.2e-07 | 0.81 | 0.06 | 0.93 | TRUE |
| 2 | GTEx | Stomach | TRIM4 | 0.34 | 0.27 | enet | 35 | 0.28 | 6.1e-14 | -4.7 | 5.2 | 1.6e-07 | 0.75 | 0.08 | 0.91 | FALSE |
| 3 | GTEx | Whole Blood | TRIM4 | 0.12 | 0.05 | lasso | 5 | 0.06 | 5.9e-06 | -4.6 | 5.2 | 2.3e-07 | 0.78 | 0.06 | 0.93 | FALSE |
| 4 | The Cancer Genome Atlas | Glioblastoma Multiforme | TRIM4 | 0.23 | 0.13 | blup | 52 | 0.20 | 1.4e-06 | -4.7 | 5.2 | 2.2e-07 | 0.77 | 0.03 | 0.95 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | TRIM4 | 0.12 | 0.16 | blup | 52 | 0.20 | 2.0e-11 | -4.6 | 5.2 | 1.7e-07 | 0.79 | 0.03 | 0.97 | FALSE |
| 6 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | TRIM4 | 0.12 | 0.14 | blup | 52 | 0.16 | 7.2e-08 | 5.1 | 5.2 | 2.0e-07 | 0.82 | 0.02 | 0.97 | FALSE |