[Hub]/) : Traits : Impedance of arm (right) :

chr7:89,097,580-90,699,073

Best TWAS P=5.45e-11 · Best GWAS P=1.07e-09 conditioned to 0.292

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial STEAP2 0.22 0.24 enet 21 0.25 2.9e-19 -4.8 5.2 2.1e-07 -0.71 0.89 0.10 FALSE
2 GTEx Brain Caudate basal ganglia STEAP2 0.30 0.08 lasso 4 0.15 4.1e-05 -5.6 6.6 5.4e-11 -0.84 0.03 0.90 TRUE
3 GTEx Cells Transformed fibroblasts GTPBP10 0.13 0.13 lasso 3 0.11 7.8e-09 -5.4 5.4 5.4e-08 -0.83 0.11 0.89 FALSE
4 GTEx Pituitary STEAP2 0.37 0.10 lasso 5 0.24 1.0e-06 -5.7 5.6 1.6e-08 -0.55 0.14 0.82 FALSE
5 ROSMAP Brain Pre-frontal Cortex GTPBP10 0.07 0.07 enet 21 0.07 1.9e-09 -5.8 6.0 2.4e-09 -0.89 0.01 0.99 FALSE
6 The Cancer Genome Atlas Bladder Urothelial Carcinoma GTPBP10 0.04 0.02 blup 61 0.03 1.1e-03 -4.4 5.7 1.5e-08 -0.55 0.04 0.58 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma GTPBP10 0.05 0.04 lasso 3 0.04 7.9e-08 -5.5 5.2 2.4e-07 -0.79 0.11 0.89 FALSE
8 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma GTPBP10 0.08 0.01 blup 61 0.03 7.8e-03 -6.1 6.0 1.7e-09 -0.83 0.01 0.93 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GTPBP10 0.05 0.02 blup 60 0.03 1.2e-04 -5.1 5.9 2.7e-09 -0.63 0.02 0.92 FALSE
10 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma STEAP2 0.06 0.02 blup 77 0.05 5.2e-04 -4.5 5.3 1.3e-07 -0.63 0.04 0.76 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma GTPBP10 0.05 0.04 lasso 2 0.02 1.5e-03 -5.4 5.4 6.2e-08 -0.83 0.09 0.82 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma GTPBP10 0.03 0.03 lasso 2 0.02 5.2e-03 -5.5 5.5 4.4e-08 -0.84 0.10 0.88 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma GTPBP10 0.08 0.10 lasso 4 0.10 1.0e-09 -5.1 6.1 1.2e-09 -0.86 0.05 0.95 FALSE