Best TWAS P=1.46e-07 · Best GWAS P=2.25e-07 conditioned to 0.0198
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Muscularis | RHOC | 0.15 | 0 | enet | 9 | 0 | 0.479 | -4.9 | -5.2 | 2.0e-07 | 0.31 | 0.04 | 0.27 | FALSE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | MOV10 | 0.03 | 0 | lasso | 9 | 0 | 0.099 | -5.2 | -5.3 | 1.5e-07 | 0.65 | 0.01 | 0.76 | TRUE |