[Hub]/) : Traits : Impedance of arm (right) : ← →

chr1:109,154,974-110,750,277

Best TWAS P=2.27e-12 · Best GWAS P=4.85e-12 conditioned to 0.403

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
38	The Cancer Genome Atlas	Stomach Adenocarcinoma	CELSR2	0.08	0.00	blup	62	0.02	8.1e-03	-6.9	-7.0	2.3e-12	0.61	0.01	0.42	TRUE
5	GTEx	Colon Sigmoid	SYPL2	0.15	0.06	enet	16	0.06	5.2e-03	-6.5	-6.6	5.6e-11	0.76	0.08	0.82	TRUE
36	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	MYBPHL	0.16	0.18	enet	10	0.17	2.3e-11	-6.9	-7.0	2.3e-12	0.99	0.01	0.99	FALSE
15	GTEx	Ovary	ATXN7L2	0.18	0.18	enet	17	0.13	5.6e-04	-6.9	7.0	2.6e-12	-0.99	0.03	0.94	FALSE
24	NTR	Blood	SORT1	0.05	0.06	lasso	6	0.06	2.1e-17	-6.9	-6.9	4.1e-12	0.99	0.02	0.98	FALSE
8	GTEx	Liver	SYPL2	0.34	0.27	lasso	5	0.30	4.6e-09	-6.4	-6.9	4.4e-12	0.88	0.04	0.96	FALSE
19	GTEx	Testis	SYPL2	0.45	0.50	enet	22	0.54	5.0e-28	-6.7	6.9	5.9e-12	-0.99	0.03	0.97	FALSE
17	GTEx	Stomach	SYPL2	0.23	0.18	lasso	8	0.21	2.3e-10	-6.4	-6.9	6.6e-12	0.90	0.04	0.96	FALSE
16	GTEx	Pancreas	SYPL2	0.28	0.23	lasso	5	0.19	2.0e-08	-6.5	-6.8	9.3e-12	0.92	0.05	0.95	FALSE
14	GTEx	Ovary	SYPL2	0.39	0.44	lasso	5	0.46	8.8e-13	-6.9	6.8	9.8e-12	-0.98	0.03	0.97	FALSE
29	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SYPL2	0.03	0.05	lasso	4	0.05	6.6e-06	-6.7	-6.8	1.0e-11	0.98	0.01	0.99	FALSE
31	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	MYBPHL	0.09	0.07	blup	46	0.06	5.7e-04	-6.5	-6.8	1.1e-11	0.80	0.01	0.78	FALSE
20	GTEx	Testis	ATXN7L2	0.28	0.34	lasso	4	0.33	3.7e-15	-6.8	6.8	1.2e-11	-0.99	0.02	0.98	FALSE
23	METSIM	Adipose	SYPL2	0.06	0.06	blup	418	0.05	4.3e-08	-6.3	-6.8	1.3e-11	0.80	0.30	0.70	FALSE
37	The Cancer Genome Atlas	Prostate Adenocarcinoma	SYPL2	0.08	0.08	blup	44	0.10	1.9e-10	-6.4	-6.8	1.3e-11	0.92	0.04	0.96	FALSE
13	GTEx	Muscle Skeletal	CYB561D1	0.07	0.00	lasso	3	0.00	7.2e-01	-6.9	6.8	1.5e-11	-0.99	0.03	0.91	FALSE
32	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	SYPL2	0.18	0.19	blup	45	0.18	4.7e-09	-6.8	-6.7	2.3e-11	0.95	0.01	0.99	FALSE
4	GTEx	Brain Cerebellum	SYPL2	0.16	0.02	enet	9	0.03	5.1e-02	-6.4	-6.5	6.0e-11	0.92	0.04	0.88	FALSE
42	The Cancer Genome Atlas	Thyroid Carcinoma	ATXN7L2	0.06	0.06	lasso	3	0.05	6.6e-06	-6.4	6.5	6.8e-11	-0.94	0.02	0.98	FALSE
12	GTEx	Muscle Skeletal	SYPL2	0.20	0.21	lasso	2	0.21	1.5e-20	-6.3	-6.3	2.5e-10	0.77	0.43	0.57	FALSE
21	GTEx	Thyroid	ATXN7L2	0.15	0.15	lasso	6	0.15	1.0e-11	-6.3	6.3	3.4e-10	-0.77	0.28	0.72	FALSE
18	GTEx	Testis	SORT1	0.25	0.17	lasso	6	0.17	5.2e-08	-6.5	-6.2	5.5e-10	0.84	0.08	0.92	FALSE
33	The Cancer Genome Atlas	Lung Adenocarcinoma	SYPL2	0.09	0.14	enet	13	0.14	1.3e-16	-6.5	-6.2	7.9e-10	0.88	0.04	0.96	FALSE
11	GTEx	Lung	SYPL2	0.24	0.20	enet	16	0.28	1.6e-21	-6.5	-6.1	8.9e-10	0.84	0.18	0.82	FALSE
2	GTEx	Brain Cerebellar Hemisphere	SYPL2	0.28	0.04	lasso	5	0.09	2.7e-03	-6.4	-6.1	9.3e-10	0.90	0.06	0.89	FALSE
39	The Cancer Genome Atlas	Stomach Adenocarcinoma	SORT1	0.04	0.01	blup	60	0.03	4.4e-03	-3.1	-6.1	1.0e-09	0.75	0.02	0.31	FALSE
35	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	AMIGO1	0.06	0.00	blup	46	0.02	9.5e-03	-5.0	-6.0	1.6e-09	0.68	0.04	0.25	FALSE
34	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SYPL2	0.05	0.06	blup	45	0.06	4.4e-07	-6.7	-6.0	1.8e-09	0.90	0.02	0.98	FALSE
30	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SYPL2	0.04	0.04	blup	45	0.04	3.6e-03	-6.3	6.0	1.9e-09	-0.88	0.02	0.59	FALSE
6	GTEx	Esophagus Mucosa	SYPL2	0.10	0.00	enet	26	0.03	4.5e-03	-6.4	-6.0	2.2e-09	0.78	0.06	0.86	FALSE
9	GTEx	Liver	ATXN7L2	0.39	0.04	lasso	12	0.21	1.3e-06	-6.7	-6.0	2.3e-09	0.74	0.04	0.88	FALSE
43	The Cancer Genome Atlas	Thyroid Carcinoma	SYPL2	0.07	0.04	blup	45	0.03	4.9e-04	-6.4	5.9	3.3e-09	-0.89	0.02	0.97	FALSE
40	The Cancer Genome Atlas	Stomach Adenocarcinoma	SYPL2	0.05	0.02	blup	45	0.03	2.6e-03	-6.4	-5.8	5.2e-09	0.87	0.02	0.78	FALSE
1	GTEx	Brain Caudate basal ganglia	AMIGO1	0.17	0.00	enet	10	0.00	4.4e-01	5.1	-5.7	1.3e-08	0.56	0.08	0.18	FALSE
22	GTEx	Uterus	SYPL2	0.29	0.13	lasso	7	0.04	5.1e-02	-6.5	5.7	1.6e-08	-0.85	0.04	0.70	FALSE
3	GTEx	Brain Cerebellar Hemisphere	ATXN7L2	0.24	-0.01	enet	9	-0.01	5.3e-01	-3.0	-5.6	1.7e-08	0.64	0.04	0.33	FALSE
7	GTEx	Esophagus Muscularis	SYPL2	0.32	0.23	lasso	10	0.37	6.8e-24	-6.9	-5.6	2.5e-08	0.81	0.03	0.97	FALSE
26	The Cancer Genome Atlas	Breast Invasive Carcinoma	SYPL2	0.06	0.07	blup	45	0.08	8.5e-16	-6.5	-5.6	2.5e-08	0.86	0.04	0.96	FALSE
28	The Cancer Genome Atlas	Glioblastoma Multiforme	AMIGO1	0.20	0.05	lasso	7	0.07	3.1e-03	-5.0	-5.3	1.2e-07	0.51	0.04	0.18	FALSE
41	The Cancer Genome Atlas	Testicular Germ Cell Tumors	AMIGO1	0.14	0.14	blup	46	0.14	1.1e-05	-3.9	-5.3	1.4e-07	0.58	0.39	0.36	FALSE
10	GTEx	Liver	AMIGO1	0.28	0.13	lasso	7	0.15	6.9e-05	-3.9	-5.2	2.5e-07	0.50	0.24	0.20	FALSE
25	ROSMAP	Brain Pre-frontal Cortex	SYPL2	0.03	0.01	lasso	3	0.01	9.8e-03	-6.3	-5.1	2.8e-07	0.67	0.07	0.63	FALSE
27	The Cancer Genome Atlas	Esophageal Carcinoma	AMIGO1	0.24	0.08	blup	46	0.18	3.0e-06	-3.7	-5.1	3.0e-07	0.56	0.10	0.26	FALSE