Best TWAS P=9.92e-09 · Best GWAS P=6.06e-08 conditioned to 0.36
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | DPYSL4 | 0.31 | 0.19 | lasso | 10 | 0.18 | 3.4e-09 | -5.4 | -5.5 | 5.0e-08 | 0.93 | 0.00 | 1.00 | FALSE |
2 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | DPYSL4 | 0.13 | 0.11 | enet | 7 | 0.08 | 2.0e-04 | -5.4 | -5.5 | 3.5e-08 | 0.98 | 0.00 | 0.99 | FALSE |
3 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | DPYSL4 | 0.17 | 0.12 | blup | 64 | 0.11 | 1.3e-04 | 4.9 | -5.7 | 9.9e-09 | 0.86 | 0.01 | 0.98 | TRUE |