Best TWAS P=1.05e-11 · Best GWAS P=9.17e-11 conditioned to 0.000211
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | TRIM8 | 0.34 | -0.01 | enet | 25 | 0.07 | 0.0047 | 2.5 | 6.0 | 1.5e-09 | 0.37 | 0.06 | 0.44 | FALSE |
| 2 | GTEx | Brain Frontal Cortex BA9 | NFKB2 | 0.27 | 0.00 | lasso | 5 | 0.00 | 0.3260 | -3.7 | -5.2 | 1.8e-07 | -0.15 | 0.05 | 0.20 | TRUE |
| 3 | GTEx | Liver | ACTR1A | 0.15 | 0.00 | lasso | 10 | 0.00 | 0.4600 | 5.5 | 6.8 | 1.0e-11 | 0.36 | 0.07 | 0.12 | TRUE |
| 4 | GTEx | Thyroid | OBFC1 | 0.09 | 0.00 | enet | 15 | 0.01 | 0.1060 | 5.4 | -6.0 | 2.6e-09 | 0.03 | 0.01 | 0.94 | TRUE |