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chr11:198,510-1,479,601

Best TWAS P=2.64e-11 · Best GWAS P=1.55e-08 conditioned to 0.0122

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	PSMD13	0.23	0.28	bslmm	302	0.28	2.9e-34	5.6	5.2	1.8e-07	0.99	0.01	0.99	FALSE
2	CommonMind	Brain Pre-frontal Cortex	RIC8A	0.12	0.13	lasso	14	0.15	9.4e-18	5.6	5.7	1.6e-08	0.91	0.01	0.99	FALSE
3	GTEx	Adipose Subcutaneous	PSMD13	0.17	0.23	lasso	11	0.23	1.7e-18	5.4	5.5	3.4e-08	1.00	0.01	0.99	FALSE
4	GTEx	Adrenal Gland	PSMD13	0.21	0.10	lasso	7	0.07	2.1e-03	5.7	5.2	2.2e-07	0.98	0.01	0.86	FALSE
5	GTEx	Artery Aorta	PSMD13	0.22	0.24	enet	13	0.30	1.2e-16	5.6	6.7	2.6e-11	0.95	0.01	0.99	TRUE
6	GTEx	Artery Coronary	PSMD13	0.19	0.02	enet	18	0.08	1.6e-03	5.4	6.4	2.1e-10	0.82	0.01	0.92	FALSE
7	GTEx	Brain Cerebellar Hemisphere	PSMD13	0.39	0.23	enet	22	0.30	2.3e-08	4.9	5.3	9.0e-08	0.87	0.02	0.98	FALSE
8	GTEx	Brain Cerebellum	PSMD13	0.31	0.34	lasso	7	0.36	2.2e-11	5.4	5.5	3.6e-08	0.99	0.01	0.99	FALSE
9	GTEx	Brain Frontal Cortex BA9	PSMD13	0.29	0.26	lasso	7	0.23	7.1e-07	5.6	5.5	3.0e-08	1.00	0.01	0.99	FALSE
10	GTEx	Brain Frontal Cortex BA9	AP006621.5	0.18	0.03	lasso	6	0.04	2.6e-02	4.8	-5.2	1.7e-07	-0.03	0.04	0.62	FALSE
11	GTEx	Brain Hippocampus	PSMD13	0.21	0.27	enet	13	0.26	7.1e-07	5.6	5.2	1.6e-07	0.98	0.01	0.98	FALSE
12	GTEx	Brain Hypothalamus	PSMD13	0.39	0.29	enet	17	0.33	1.8e-08	5.4	5.1	2.6e-07	0.95	0.01	0.99	FALSE
13	GTEx	Brain Nucleus accumbens basal ganglia	PSMD13	0.22	0.16	lasso	7	0.15	8.0e-05	5.7	5.3	1.1e-07	0.99	0.01	0.98	FALSE
14	GTEx	Cells EBV-transformed lymphocytes	PSMD13	0.17	0.15	lasso	9	0.09	9.7e-04	5.2	5.3	1.4e-07	0.98	0.01	0.96	FALSE
15	GTEx	Cells Transformed fibroblasts	PSMD13	0.18	0.13	enet	38	0.12	4.0e-09	5.7	5.6	2.7e-08	0.87	0.01	0.99	FALSE
16	GTEx	Colon Sigmoid	PSMD13	0.18	0.11	lasso	7	0.11	1.2e-04	5.4	5.5	4.9e-08	0.94	0.01	0.98	FALSE
17	GTEx	Colon Transverse	SIRT3	0.25	0.25	lasso	3	0.28	6.8e-14	5.7	-5.3	1.4e-07	-0.94	0.01	0.99	FALSE
18	GTEx	Colon Transverse	PSMD13	0.25	0.22	lasso	4	0.21	2.9e-10	5.6	5.5	3.7e-08	1.00	0.01	0.99	FALSE
19	GTEx	Esophagus Mucosa	PSMD13	0.14	0.15	lasso	4	0.14	2.0e-09	5.7	5.4	6.7e-08	0.99	0.01	0.99	FALSE
20	GTEx	Esophagus Muscularis	PSMD13	0.22	0.23	lasso	3	0.23	4.3e-14	5.6	5.5	4.5e-08	1.00	0.01	0.99	FALSE
21	GTEx	Lung	PSMD13	0.22	0.20	lasso	1	0.20	4.6e-15	5.6	5.6	2.7e-08	1.00	0.01	0.99	FALSE
22	GTEx	Nerve Tibial	PSMD13	0.34	0.39	lasso	8	0.37	1.5e-27	5.6	5.5	3.1e-08	1.00	0.01	0.99	FALSE
23	GTEx	Pancreas	PSMD13	0.19	0.01	lasso	10	0.03	1.6e-02	4.3	5.5	3.1e-08	0.84	0.01	0.94	FALSE
24	GTEx	Skin Not Sun Exposed Suprapubic	PSMD13	0.23	0.26	lasso	4	0.26	1.3e-14	5.7	5.6	1.8e-08	0.99	0.01	0.99	FALSE
25	GTEx	Skin Sun Exposed Lower leg	PSMD13	0.21	0.26	lasso	7	0.26	1.3e-21	5.7	5.5	3.0e-08	1.00	0.01	0.99	FALSE
26	GTEx	Spleen	PSMD13	0.38	0.36	lasso	6	0.34	1.8e-09	5.6	5.5	3.6e-08	0.99	0.01	0.99	FALSE
27	GTEx	Stomach	RP11-304M2.5	0.22	0.02	lasso	9	0.02	2.8e-02	5.7	5.7	1.1e-08	0.90	0.01	0.88	FALSE
28	GTEx	Testis	PSMD13	0.42	0.47	lasso	4	0.46	1.3e-22	5.6	5.6	2.7e-08	1.00	0.01	0.99	FALSE
29	GTEx	Thyroid	PSMD13	0.27	0.34	lasso	4	0.34	1.5e-26	5.4	5.5	3.5e-08	1.00	0.01	0.99	FALSE
30	GTEx	Vagina	PSMD13	0.26	0.15	lasso	11	0.13	8.0e-04	5.6	5.6	2.2e-08	0.99	0.01	0.92	FALSE
31	GTEx	Whole Blood	RIC8A	0.10	0.04	lasso	4	0.02	3.6e-03	5.2	5.2	1.5e-07	0.98	0.01	0.94	FALSE
32	ROSMAP	Brain Pre-frontal Cortex	PSMD13	0.41	0.43	lasso	8	0.55	5.7e-85	5.4	5.7	1.5e-08	0.90	0.01	0.99	FALSE
33	The Cancer Genome Atlas	Glioblastoma Multiforme	PSMD13	0.16	0.15	lasso	2	0.15	2.4e-05	5.4	5.4	5.6e-08	1.00	0.01	0.97	FALSE
34	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CEND1	0.06	0.02	enet	9	0.04	7.7e-06	4.4	-5.5	4.9e-08	0.02	0.12	0.70	FALSE
35	The Cancer Genome Atlas	Brain Lower Grade Glioma	PSMD13	0.07	0.07	blup	86	0.07	1.6e-08	5.2	5.2	2.4e-07	0.88	0.01	0.99	FALSE
36	The Cancer Genome Atlas	Rectum Adenocarcinoma	CHID1	0.25	0.16	blup	68	0.13	6.4e-04	4.4	5.8	7.1e-09	0.02	0.06	0.22	TRUE
37	The Cancer Genome Atlas	Testicular Germ Cell Tumors	PSMD13	0.10	0.03	blup	87	0.06	4.9e-03	5.4	5.3	1.2e-07	0.83	0.01	0.77	FALSE