[Hub]/) : Traits : Impedance of arm (right) :

chr11:198,510-1,479,601

Best TWAS P=2.64e-11 · Best GWAS P=1.55e-08 conditioned to 0.0122

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PSMD13 0.23 0.28 bslmm 302 0.28 2.9e-34 5.6 5.2 1.8e-07 0.99 0.01 0.99 FALSE
2 CommonMind Brain Pre-frontal Cortex RIC8A 0.12 0.13 lasso 14 0.15 9.4e-18 5.6 5.7 1.6e-08 0.91 0.01 0.99 FALSE
3 GTEx Adipose Subcutaneous PSMD13 0.17 0.23 lasso 11 0.23 1.7e-18 5.4 5.5 3.4e-08 1.00 0.01 0.99 FALSE
4 GTEx Adrenal Gland PSMD13 0.21 0.10 lasso 7 0.07 2.1e-03 5.7 5.2 2.2e-07 0.98 0.01 0.86 FALSE
5 GTEx Artery Aorta PSMD13 0.22 0.24 enet 13 0.30 1.2e-16 5.6 6.7 2.6e-11 0.95 0.01 0.99 TRUE
6 GTEx Artery Coronary PSMD13 0.19 0.02 enet 18 0.08 1.6e-03 5.4 6.4 2.1e-10 0.82 0.01 0.92 FALSE
7 GTEx Brain Cerebellar Hemisphere PSMD13 0.39 0.23 enet 22 0.30 2.3e-08 4.9 5.3 9.0e-08 0.87 0.02 0.98 FALSE
8 GTEx Brain Cerebellum PSMD13 0.31 0.34 lasso 7 0.36 2.2e-11 5.4 5.5 3.6e-08 0.99 0.01 0.99 FALSE
9 GTEx Brain Frontal Cortex BA9 PSMD13 0.29 0.26 lasso 7 0.23 7.1e-07 5.6 5.5 3.0e-08 1.00 0.01 0.99 FALSE
10 GTEx Brain Frontal Cortex BA9 AP006621.5 0.18 0.03 lasso 6 0.04 2.6e-02 4.8 -5.2 1.7e-07 -0.03 0.04 0.62 FALSE
11 GTEx Brain Hippocampus PSMD13 0.21 0.27 enet 13 0.26 7.1e-07 5.6 5.2 1.6e-07 0.98 0.01 0.98 FALSE
12 GTEx Brain Hypothalamus PSMD13 0.39 0.29 enet 17 0.33 1.8e-08 5.4 5.1 2.6e-07 0.95 0.01 0.99 FALSE
13 GTEx Brain Nucleus accumbens basal ganglia PSMD13 0.22 0.16 lasso 7 0.15 8.0e-05 5.7 5.3 1.1e-07 0.99 0.01 0.98 FALSE
14 GTEx Cells EBV-transformed lymphocytes PSMD13 0.17 0.15 lasso 9 0.09 9.7e-04 5.2 5.3 1.4e-07 0.98 0.01 0.96 FALSE
15 GTEx Cells Transformed fibroblasts PSMD13 0.18 0.13 enet 38 0.12 4.0e-09 5.7 5.6 2.7e-08 0.87 0.01 0.99 FALSE
16 GTEx Colon Sigmoid PSMD13 0.18 0.11 lasso 7 0.11 1.2e-04 5.4 5.5 4.9e-08 0.94 0.01 0.98 FALSE
17 GTEx Colon Transverse SIRT3 0.25 0.25 lasso 3 0.28 6.8e-14 5.7 -5.3 1.4e-07 -0.94 0.01 0.99 FALSE
18 GTEx Colon Transverse PSMD13 0.25 0.22 lasso 4 0.21 2.9e-10 5.6 5.5 3.7e-08 1.00 0.01 0.99 FALSE
19 GTEx Esophagus Mucosa PSMD13 0.14 0.15 lasso 4 0.14 2.0e-09 5.7 5.4 6.7e-08 0.99 0.01 0.99 FALSE
20 GTEx Esophagus Muscularis PSMD13 0.22 0.23 lasso 3 0.23 4.3e-14 5.6 5.5 4.5e-08 1.00 0.01 0.99 FALSE
21 GTEx Lung PSMD13 0.22 0.20 lasso 1 0.20 4.6e-15 5.6 5.6 2.7e-08 1.00 0.01 0.99 FALSE
22 GTEx Nerve Tibial PSMD13 0.34 0.39 lasso 8 0.37 1.5e-27 5.6 5.5 3.1e-08 1.00 0.01 0.99 FALSE
23 GTEx Pancreas PSMD13 0.19 0.01 lasso 10 0.03 1.6e-02 4.3 5.5 3.1e-08 0.84 0.01 0.94 FALSE
24 GTEx Skin Not Sun Exposed Suprapubic PSMD13 0.23 0.26 lasso 4 0.26 1.3e-14 5.7 5.6 1.8e-08 0.99 0.01 0.99 FALSE
25 GTEx Skin Sun Exposed Lower leg PSMD13 0.21 0.26 lasso 7 0.26 1.3e-21 5.7 5.5 3.0e-08 1.00 0.01 0.99 FALSE
26 GTEx Spleen PSMD13 0.38 0.36 lasso 6 0.34 1.8e-09 5.6 5.5 3.6e-08 0.99 0.01 0.99 FALSE
27 GTEx Stomach RP11-304M2.5 0.22 0.02 lasso 9 0.02 2.8e-02 5.7 5.7 1.1e-08 0.90 0.01 0.88 FALSE
28 GTEx Testis PSMD13 0.42 0.47 lasso 4 0.46 1.3e-22 5.6 5.6 2.7e-08 1.00 0.01 0.99 FALSE
29 GTEx Thyroid PSMD13 0.27 0.34 lasso 4 0.34 1.5e-26 5.4 5.5 3.5e-08 1.00 0.01 0.99 FALSE
30 GTEx Vagina PSMD13 0.26 0.15 lasso 11 0.13 8.0e-04 5.6 5.6 2.2e-08 0.99 0.01 0.92 FALSE
31 GTEx Whole Blood RIC8A 0.10 0.04 lasso 4 0.02 3.6e-03 5.2 5.2 1.5e-07 0.98 0.01 0.94 FALSE
32 ROSMAP Brain Pre-frontal Cortex PSMD13 0.41 0.43 lasso 8 0.55 5.7e-85 5.4 5.7 1.5e-08 0.90 0.01 0.99 FALSE
33 The Cancer Genome Atlas Glioblastoma Multiforme PSMD13 0.16 0.15 lasso 2 0.15 2.4e-05 5.4 5.4 5.6e-08 1.00 0.01 0.97 FALSE
34 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CEND1 0.06 0.02 enet 9 0.04 7.7e-06 4.4 -5.5 4.9e-08 0.02 0.12 0.70 FALSE
35 The Cancer Genome Atlas Brain Lower Grade Glioma PSMD13 0.07 0.07 blup 86 0.07 1.6e-08 5.2 5.2 2.4e-07 0.88 0.01 0.99 FALSE
36 The Cancer Genome Atlas Rectum Adenocarcinoma CHID1 0.25 0.16 blup 68 0.13 6.4e-04 4.4 5.8 7.1e-09 0.02 0.06 0.22 TRUE
37 The Cancer Genome Atlas Testicular Germ Cell Tumors PSMD13 0.10 0.03 blup 87 0.06 4.9e-03 5.4 5.3 1.2e-07 0.83 0.01 0.77 FALSE