Best TWAS P=9.67e-12 · Best GWAS P=4.47e-27 conditioned to 1.15e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | LIN7C | 0.08 | 0.06 | lasso | 1 | 0.04 | 0.00041 | -5.7 | -5.7 | 1.2e-08 | -0.26 | 0.86 | 0.00 | FALSE |
| 2 | GTEx | Brain Putamen basal ganglia | BDNF-AS | 0.22 | 0.17 | lasso | 4 | 0.13 | 0.00055 | 5.4 | -5.8 | 5.4e-09 | -0.65 | 0.04 | 0.82 | FALSE |
| 3 | NTR | Blood | LIN7C | 0.01 | 0.00 | lasso | 3 | 0.01 | 0.00218 | -5.8 | 5.2 | 1.6e-07 | 0.17 | 0.52 | 0.01 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | BDNFOS | 0.03 | 0.01 | blup | 83 | 0.02 | 0.00143 | 2.1 | -6.8 | 9.7e-12 | -0.76 | 0.02 | 0.94 | TRUE |