[Hub]/) : Traits : Impedance of arm (right) : ← →

chr11:16,343,081-18,106,069

Best TWAS P=6.1e-11 · Best GWAS P=9.1e-12 conditioned to 0.03

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
10	GTEx	Skin Sun Exposed Lower leg	KCNJ11	0.23	0.09	lasso	10	0.12	1.7e-10	6.7	-6.5	6.1e-11	-0.89	0.00	1.00	TRUE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DKFZp686O24166	0.05	0.03	blup	71	0.04	1.2e-05	-4.5	-6.5	7.4e-11	-0.81	0.01	0.98	FALSE
1	CommonMind	Brain Pre-frontal Cortex	KCNJ11	0.04	0.03	lasso	3	0.03	2.6e-04	6.2	6.4	1.1e-10	0.93	0.01	0.98	FALSE
12	GTEx	Skin Sun Exposed Lower leg	RP1-239B22.5	0.06	0.06	lasso	2	0.07	8.6e-07	-5.0	-6.4	1.3e-10	-0.83	0.02	0.98	FALSE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DKFZp686O24166	0.03	0.01	blup	72	0.03	2.4e-04	6.7	-6.3	3.6e-10	-0.83	0.01	0.96	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	KCNJ11	0.18	0.07	lasso	6	0.12	7.0e-07	6.2	-6.2	5.0e-10	-0.85	0.01	0.99	FALSE
6	GTEx	Esophagus Mucosa	RP1-239B22.5	0.28	0.28	enet	47	0.32	2.9e-22	-4.4	-6.1	1.1e-09	-0.74	0.96	0.04	FALSE
4	GTEx	Esophagus Mucosa	KCNJ11	0.27	0.16	lasso	8	0.22	1.6e-14	-4.3	-6.0	2.0e-09	-0.77	0.28	0.72	FALSE
13	GTEx	Thyroid	RP1-239B22.5	0.08	0.07	enet	16	0.08	1.8e-06	6.8	-5.9	2.8e-09	-0.84	0.00	0.99	FALSE
18	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	DKFZp686O24166	0.08	0.07	lasso	4	0.05	1.2e-03	-4.7	-5.9	3.5e-09	-0.72	0.03	0.93	FALSE
5	GTEx	Esophagus Mucosa	NCR3LG1	0.38	0.38	enet	39	0.42	3.7e-30	-4.3	-5.9	3.6e-09	-0.72	1.00	0.00	FALSE
7	GTEx	Nerve Tibial	RP1-239B22.5	0.11	0.08	lasso	2	0.08	2.9e-06	-3.7	-5.8	7.3e-09	-0.74	0.02	0.96	FALSE
2	GTEx	Adipose Subcutaneous	RP1-239B22.5	0.11	0.06	enet	21	0.07	1.5e-06	6.6	-5.6	2.8e-08	-0.80	0.01	0.99	FALSE
3	GTEx	Cells Transformed fibroblasts	PIK3C2A	0.10	0.08	lasso	4	0.08	1.3e-06	5.4	-5.5	4.3e-08	-0.60	0.82	0.06	FALSE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	DKFZp686O24166	0.04	0.01	blup	71	0.02	1.5e-03	5.8	-5.4	5.8e-08	-0.80	0.01	0.88	FALSE
15	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	DKFZp686O24166	0.04	0.00	blup	71	0.02	7.1e-03	-4.8	-5.3	8.9e-08	-0.79	0.01	0.81	FALSE
11	GTEx	Skin Sun Exposed Lower leg	NCR3LG1	0.12	0.12	lasso	5	0.13	5.0e-11	-5.0	-5.3	1.2e-07	-0.53	0.97	0.03	FALSE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	NUCB2	0.17	0.06	blup	66	0.06	2.8e-07	4.4	5.3	1.2e-07	0.71	0.76	0.24	FALSE
14	ROSMAP	Brain Pre-frontal Cortex	KCNJ11	0.05	0.06	enet	6	0.05	3.0e-07	4.8	5.3	1.4e-07	0.73	0.19	0.79	FALSE
9	GTEx	Skin Sun Exposed Lower leg	OR7E14P	0.11	0.05	lasso	6	0.08	4.3e-07	5.1	-5.1	2.8e-07	-0.48	0.86	0.04	FALSE