[Hub]/) : Traits : Impedance of arm (right) :

chr11:16,343,081-18,106,069

Best TWAS P=6.1e-11 · Best GWAS P=9.1e-12 conditioned to 0.03

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex KCNJ11 0.04 0.03 lasso 3 0.03 2.6e-04 6.2 6.4 1.1e-10 0.93 0.01 0.98 FALSE
2 GTEx Adipose Subcutaneous RP1-239B22.5 0.11 0.06 enet 21 0.07 1.5e-06 6.6 -5.6 2.8e-08 -0.80 0.01 0.99 FALSE
3 GTEx Cells Transformed fibroblasts PIK3C2A 0.10 0.08 lasso 4 0.08 1.3e-06 5.4 -5.5 4.3e-08 -0.60 0.82 0.06 FALSE
4 GTEx Esophagus Mucosa KCNJ11 0.27 0.16 lasso 8 0.22 1.6e-14 -4.3 -6.0 2.0e-09 -0.77 0.28 0.72 FALSE
5 GTEx Esophagus Mucosa NCR3LG1 0.38 0.38 enet 39 0.42 3.7e-30 -4.3 -5.9 3.6e-09 -0.72 1.00 0.00 FALSE
6 GTEx Esophagus Mucosa RP1-239B22.5 0.28 0.28 enet 47 0.32 2.9e-22 -4.4 -6.1 1.1e-09 -0.74 0.96 0.04 FALSE
7 GTEx Nerve Tibial RP1-239B22.5 0.11 0.08 lasso 2 0.08 2.9e-06 -3.7 -5.8 7.3e-09 -0.74 0.02 0.96 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic KCNJ11 0.18 0.07 lasso 6 0.12 7.0e-07 6.2 -6.2 5.0e-10 -0.85 0.01 0.99 FALSE
9 GTEx Skin Sun Exposed Lower leg OR7E14P 0.11 0.05 lasso 6 0.08 4.3e-07 5.1 -5.1 2.8e-07 -0.48 0.86 0.04 FALSE
10 GTEx Skin Sun Exposed Lower leg KCNJ11 0.23 0.09 lasso 10 0.12 1.7e-10 6.7 -6.5 6.1e-11 -0.89 0.00 1.00 TRUE
11 GTEx Skin Sun Exposed Lower leg NCR3LG1 0.12 0.12 lasso 5 0.13 5.0e-11 -5.0 -5.3 1.2e-07 -0.53 0.97 0.03 FALSE
12 GTEx Skin Sun Exposed Lower leg RP1-239B22.5 0.06 0.06 lasso 2 0.07 8.6e-07 -5.0 -6.4 1.3e-10 -0.83 0.02 0.98 FALSE
13 GTEx Thyroid RP1-239B22.5 0.08 0.07 enet 16 0.08 1.8e-06 6.8 -5.9 2.8e-09 -0.84 0.00 0.99 FALSE
14 ROSMAP Brain Pre-frontal Cortex KCNJ11 0.05 0.06 enet 6 0.05 3.0e-07 4.8 5.3 1.4e-07 0.73 0.19 0.79 FALSE
15 The Cancer Genome Atlas Bladder Urothelial Carcinoma DKFZp686O24166 0.04 0.00 blup 71 0.02 7.1e-03 -4.8 -5.3 8.9e-08 -0.79 0.01 0.81 FALSE
16 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DKFZp686O24166 0.05 0.03 blup 71 0.04 1.2e-05 -4.5 -6.5 7.4e-11 -0.81 0.01 0.98 FALSE
17 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DKFZp686O24166 0.03 0.01 blup 72 0.03 2.4e-04 6.7 -6.3 3.6e-10 -0.83 0.01 0.96 FALSE
18 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma DKFZp686O24166 0.08 0.07 lasso 4 0.05 1.2e-03 -4.7 -5.9 3.5e-09 -0.72 0.03 0.93 FALSE
19 The Cancer Genome Atlas Lung Adenocarcinoma DKFZp686O24166 0.04 0.01 blup 71 0.02 1.5e-03 5.8 -5.4 5.8e-08 -0.80 0.01 0.88 FALSE
20 The Cancer Genome Atlas Prostate Adenocarcinoma NUCB2 0.17 0.06 blup 66 0.06 2.8e-07 4.4 5.3 1.2e-07 0.71 0.76 0.24 FALSE