[Hub]/) : Traits : Impedance of arm (right) :

chr11:61,627,881-63,284,510

Best TWAS P=9.52e-17 · Best GWAS P=7.76e-16 conditioned to 0.0125

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous ROM1 0.25 0.17 lasso 3 0.18 1.5e-14 -7.4 7.6 2.5e-14 -0.78 0.48 0.52 FALSE
2 GTEx Adipose Visceral Omentum ROM1 0.29 0.16 lasso 8 0.23 3.7e-12 -7.0 8.0 1.4e-15 -0.81 0.21 0.79 FALSE
3 GTEx Artery Aorta ROM1 0.18 0.17 lasso 7 0.16 3.3e-09 -6.8 6.9 4.5e-12 -0.71 0.68 0.32 FALSE
4 GTEx Artery Tibial ROM1 0.14 0.05 lasso 6 0.03 2.5e-03 -6.9 7.0 2.6e-12 -0.74 0.24 0.63 FALSE
5 GTEx Breast Mammary Tissue ROM1 0.10 0.09 lasso 5 0.06 5.4e-04 -6.8 7.0 2.6e-12 -0.72 0.38 0.53 FALSE
6 GTEx Breast Mammary Tissue (Male) ROM1 0.17 0.00 enet 18 0.01 2.2e-01 -6.9 5.8 8.2e-09 -0.55 0.04 0.24 FALSE
7 GTEx Breast Mammary Tissue (Female) ROM1 0.16 0.02 lasso 4 0.04 2.9e-02 -7.0 7.0 2.6e-12 -0.69 0.08 0.42 FALSE
8 GTEx Cells EBV-transformed lymphocytes EML3 0.33 0.22 lasso 8 0.21 1.6e-07 -6.9 -6.5 6.3e-11 0.65 0.67 0.28 FALSE
9 GTEx Cells Transformed fibroblasts MTA2 0.06 0.09 lasso 1 0.07 3.0e-06 -7.3 -7.3 2.3e-13 0.82 0.43 0.51 FALSE
10 GTEx Cells Transformed fibroblasts EML3 0.19 0.16 lasso 9 0.18 7.3e-14 -7.3 -7.5 6.2e-14 0.81 0.65 0.35 FALSE
11 GTEx Cells Transformed fibroblasts HNRNPUL2 0.11 0.04 enet 14 0.05 9.8e-05 -3.2 6.0 2.1e-09 -0.84 0.03 0.97 FALSE
12 GTEx Esophagus Mucosa MTA2 0.29 0.34 lasso 5 0.33 6.9e-23 -6.9 -7.0 3.1e-12 0.71 0.95 0.05 FALSE
13 GTEx Esophagus Mucosa EML3 0.40 0.43 lasso 8 0.46 1.8e-33 -6.8 -7.1 1.3e-12 0.72 0.95 0.05 FALSE
14 GTEx Lung ROM1 0.25 0.18 enet 13 0.20 2.2e-15 -6.9 7.6 3.3e-14 -0.78 0.87 0.13 FALSE
15 GTEx Lung EML3 0.07 0.04 lasso 3 0.01 2.5e-02 -6.9 -6.9 5.0e-12 0.71 0.24 0.39 FALSE
16 GTEx Nerve Tibial ROM1 0.15 0.06 lasso 7 0.06 2.9e-05 -7.4 5.9 3.2e-09 -0.64 0.10 0.88 FALSE
17 GTEx Nerve Tibial EML3 0.17 0.10 lasso 4 0.09 3.9e-07 -6.9 -7.5 4.9e-14 0.77 0.14 0.86 FALSE
18 GTEx Nerve Tibial B3GAT3 0.18 0.11 lasso 3 0.09 4.7e-07 -8.0 -7.9 2.0e-15 0.97 0.00 1.00 FALSE
19 GTEx Ovary ROM1 0.25 0.00 lasso 5 0.00 3.3e-01 -7.3 7.8 6.4e-15 -0.81 0.07 0.28 FALSE
20 GTEx Pituitary STX5 0.22 0.11 lasso 3 0.11 9.7e-04 -2.5 6.5 6.5e-11 -0.55 0.05 0.44 FALSE
21 GTEx Skin Not Sun Exposed Suprapubic ROM1 0.15 0.08 lasso 1 0.06 2.8e-04 -8.1 8.1 7.8e-16 -1.00 0.01 0.96 FALSE
22 GTEx Skin Not Sun Exposed Suprapubic EML3 0.20 0.19 lasso 3 0.24 2.7e-13 -6.9 -7.6 3.7e-14 0.78 0.14 0.86 FALSE
23 GTEx Skin Not Sun Exposed Suprapubic B3GAT3 0.18 0.11 lasso 3 0.11 9.8e-07 -8.0 -8.1 4.1e-16 0.96 0.00 1.00 FALSE
24 GTEx Skin Sun Exposed Lower leg MTA2 0.14 0.04 enet 21 0.05 3.1e-05 -7.4 -5.9 3.2e-09 0.73 0.08 0.89 FALSE
25 GTEx Skin Sun Exposed Lower leg ROM1 0.13 0.11 lasso 4 0.10 9.7e-09 -6.9 6.7 1.6e-11 -0.70 0.63 0.37 FALSE
26 GTEx Skin Sun Exposed Lower leg EML3 0.32 0.25 enet 19 0.26 8.0e-22 -6.9 -7.7 1.4e-14 0.71 0.92 0.08 FALSE
27 GTEx Spleen GANAB 0.35 -0.01 lasso 9 0.01 1.3e-01 -6.9 -6.4 1.4e-10 0.71 0.05 0.42 FALSE
28 GTEx Spleen MTA2 0.26 0.07 enet 19 0.07 8.7e-03 -7.0 -6.5 9.5e-11 0.68 0.05 0.76 FALSE
29 GTEx Stomach EML3 0.11 0.04 enet 5 0.03 2.1e-02 -7.3 -7.3 2.8e-13 0.79 0.08 0.44 FALSE
30 GTEx Testis EML3 0.27 0.22 enet 15 0.29 2.7e-13 -6.9 -7.5 6.6e-14 0.82 0.38 0.62 FALSE
31 GTEx Thyroid ROM1 0.17 0.16 lasso 8 0.16 3.6e-12 -6.9 7.2 7.8e-13 -0.72 0.72 0.28 FALSE
32 GTEx Thyroid EML3 0.10 0.11 lasso 4 0.10 5.9e-08 -6.9 -6.9 6.8e-12 0.70 0.36 0.63 FALSE
33 GTEx Thyroid B3GAT3 0.18 0.09 lasso 5 0.12 1.4e-09 -8.0 -7.9 2.1e-15 0.90 0.00 1.00 FALSE
34 GTEx Whole Blood EML3 0.17 0.09 lasso 7 0.08 6.3e-08 -6.8 -7.1 1.7e-12 0.74 0.78 0.22 FALSE
35 METSIM Adipose B3GAT3 0.08 0.06 enet 16 0.07 5.4e-11 -7.7 -7.4 2.0e-13 0.82 0.02 0.98 FALSE
36 METSIM Adipose EEF1G 0.08 0.05 bslmm 375 0.06 4.5e-09 -7.4 6.4 1.6e-10 -0.66 0.61 0.39 FALSE
37 METSIM Adipose EML3 0.15 0.14 bslmm 376 0.14 1.9e-20 -6.8 -6.5 6.9e-11 0.68 0.94 0.06 FALSE
38 METSIM Adipose ROM1 0.05 0.02 enet 17 0.02 9.9e-05 -6.9 6.2 4.9e-10 -0.57 0.48 0.48 FALSE
39 METSIM Adipose TTC9C 0.07 0.07 enet 25 0.08 1.4e-12 -3.3 -5.3 1.2e-07 0.71 0.73 0.27 FALSE
40 YFS Blood EEF1G 0.30 0.45 lasso 6 0.45 3.6e-166 -6.8 6.8 7.7e-12 -0.71 0.97 0.03 FALSE
41 YFS Blood EML3 0.20 0.31 lasso 12 0.33 1.3e-110 -7.4 -7.5 7.9e-14 0.76 0.61 0.39 FALSE
42 YFS Blood INTS5 0.09 0.12 lasso 4 0.12 1.9e-38 -8.0 -8.3 1.3e-16 0.97 0.00 1.00 FALSE
43 The Cancer Genome Atlas Bladder Urothelial Carcinoma EEF1G 0.04 0.05 lasso 1 0.04 1.1e-04 -7.4 7.4 1.3e-13 -0.73 0.05 0.90 FALSE
44 The Cancer Genome Atlas Breast Invasive Carcinoma C11orf83 0.01 0.00 blup 23 0.01 4.2e-03 -7.7 6.9 6.3e-12 -0.86 0.01 0.62 FALSE
45 The Cancer Genome Atlas Breast Invasive Carcinoma EEF1G 0.02 0.04 lasso 2 0.03 6.3e-07 -6.8 6.9 6.8e-12 -0.71 0.24 0.76 FALSE
46 The Cancer Genome Atlas Breast Invasive Carcinoma EML3 0.02 0.02 lasso 4 0.02 2.5e-05 -7.4 -7.3 2.0e-13 0.73 0.28 0.70 FALSE
47 The Cancer Genome Atlas Breast Invasive Carcinoma ROM1 0.01 0.02 enet 4 0.02 2.4e-04 -7.4 7.6 3.2e-14 -0.74 0.09 0.75 FALSE
48 The Cancer Genome Atlas Colon Adenocarcinoma EEF1G 0.07 0.11 lasso 1 0.11 9.2e-07 -6.9 6.9 5.2e-12 -0.69 0.11 0.89 FALSE
49 The Cancer Genome Atlas Colon Adenocarcinoma EML3 0.07 0.03 blup 29 0.05 6.5e-04 -7.3 -6.7 2.8e-11 0.69 0.10 0.33 FALSE
50 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma EEF1G 0.10 0.09 blup 26 0.09 9.8e-11 -6.9 6.1 9.6e-10 -0.61 0.30 0.70 FALSE
51 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma EML3 0.06 0.05 blup 27 0.06 7.6e-07 -7.7 -7.2 8.3e-13 0.77 0.03 0.97 FALSE
52 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ROM1 0.04 0.02 blup 22 0.02 6.2e-03 -7.3 6.1 1.1e-09 -0.68 0.04 0.28 FALSE
53 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma EEF1G 0.11 0.12 blup 27 0.13 5.5e-14 -6.9 7.2 7.9e-13 -0.73 0.31 0.69 FALSE
54 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma EML3 0.04 0.06 lasso 3 0.06 1.7e-07 -6.9 -6.9 5.9e-12 0.70 0.60 0.40 FALSE
55 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma EEF1G 0.07 0.04 blup 28 0.07 9.8e-05 -7.3 7.3 2.8e-13 -0.74 0.05 0.80 FALSE
56 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma EML3 0.06 0.09 lasso 2 0.08 1.6e-05 -7.7 -7.8 8.9e-15 0.79 0.02 0.97 FALSE
57 The Cancer Genome Atlas Brain Lower Grade Glioma C11orf83 0.02 0.01 blup 24 0.01 1.5e-02 -7.7 7.4 1.2e-13 -0.86 0.01 0.84 FALSE
58 The Cancer Genome Atlas Brain Lower Grade Glioma EEF1G 0.06 0.07 blup 27 0.07 8.1e-09 -6.8 6.8 1.0e-11 -0.75 0.04 0.96 FALSE
59 The Cancer Genome Atlas Brain Lower Grade Glioma EML3 0.03 0.04 blup 28 0.03 7.6e-05 -7.4 -7.1 1.0e-12 0.74 0.18 0.78 FALSE
60 The Cancer Genome Atlas Liver Hepatocellular Carcinoma EEF1G 0.06 0.03 blup 27 0.04 4.5e-03 -7.7 7.7 1.0e-14 -0.78 0.01 0.79 FALSE
61 The Cancer Genome Atlas Lung Adenocarcinoma EEF1G 0.06 0.08 lasso 8 0.08 5.9e-10 -6.8 7.3 3.4e-13 -0.78 0.11 0.89 FALSE
62 The Cancer Genome Atlas Lung Adenocarcinoma EML3 0.03 0.03 blup 28 0.03 8.4e-05 -6.8 -7.7 1.8e-14 0.76 0.29 0.69 FALSE
63 The Cancer Genome Atlas Lung Adenocarcinoma ROM1 0.04 0.04 blup 23 0.04 9.5e-06 -6.8 7.4 1.6e-13 -0.80 0.23 0.76 FALSE
64 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C11orf83 0.07 0.01 blup 24 0.01 1.0e-02 -8.0 7.5 6.1e-14 -0.80 0.00 0.90 FALSE
65 The Cancer Genome Atlas Lung Squamous Cell Carcinoma EEF1G 0.08 0.13 lasso 4 0.12 3.1e-13 -6.8 6.8 7.5e-12 -0.71 0.35 0.65 FALSE
66 The Cancer Genome Atlas Lung Squamous Cell Carcinoma EML3 0.04 0.05 blup 27 0.05 3.5e-06 -7.4 -6.7 2.0e-11 0.75 0.10 0.89 FALSE
67 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma EML3 0.03 0.02 blup 27 0.03 3.5e-03 -7.4 -7.8 7.4e-15 0.81 0.02 0.73 FALSE
68 The Cancer Genome Atlas Pancreatic Adenocarcinoma EEF1G 0.08 0.08 blup 27 0.05 3.6e-03 -6.8 6.6 5.1e-11 -0.68 0.10 0.63 FALSE
69 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma EEF1G 0.08 0.00 blup 27 0.04 1.3e-02 -6.8 6.5 6.7e-11 -0.68 0.03 0.65 FALSE
70 The Cancer Genome Atlas Prostate Adenocarcinoma C11orf83 0.03 0.03 blup 24 0.02 5.5e-03 -8.0 7.4 1.8e-13 -0.94 0.00 0.99 FALSE
71 The Cancer Genome Atlas Prostate Adenocarcinoma EEF1G 0.08 0.13 lasso 2 0.12 1.8e-12 -6.8 6.8 7.4e-12 -0.71 0.35 0.65 FALSE
72 The Cancer Genome Atlas Prostate Adenocarcinoma EML3 0.09 0.14 lasso 1 0.14 3.4e-14 -7.4 -7.4 1.3e-13 0.73 0.16 0.84 FALSE
73 The Cancer Genome Atlas Rectum Adenocarcinoma EML3 0.36 0.08 blup 27 0.19 3.7e-05 -7.4 -5.4 6.7e-08 0.55 0.05 0.31 FALSE
74 The Cancer Genome Atlas Soft Tissue Sarcoma ROM1 0.06 0.05 blup 24 0.03 8.1e-03 -6.8 7.3 2.1e-13 -0.73 0.06 0.27 FALSE
75 The Cancer Genome Atlas Skin Cutaneous Melanoma EML3 0.32 0.03 lasso 2 0.07 4.9e-03 -7.3 -5.4 8.0e-08 0.77 0.02 0.36 FALSE
76 The Cancer Genome Atlas Stomach Adenocarcinoma EEF1G 0.05 0.07 blup 27 0.07 1.7e-05 -6.9 6.9 4.4e-12 -0.72 0.11 0.89 FALSE
77 The Cancer Genome Atlas Stomach Adenocarcinoma ROM1 0.05 0.08 lasso 3 0.08 3.1e-06 -6.9 7.1 1.1e-12 -0.74 0.23 0.75 FALSE
78 The Cancer Genome Atlas Thyroid Carcinoma EEF1G 0.15 0.27 blup 27 0.28 3.6e-27 -6.9 6.2 7.1e-10 -0.66 0.28 0.72 FALSE
79 The Cancer Genome Atlas Thyroid Carcinoma EML3 0.11 0.10 blup 28 0.12 2.3e-11 -7.4 -8.3 9.5e-17 0.78 0.03 0.97 TRUE
80 The Cancer Genome Atlas Thyroid Carcinoma ROM1 0.03 0.02 blup 23 0.02 1.1e-02 -6.9 7.3 3.4e-13 -0.77 0.05 0.62 FALSE