[Hub]/) : Traits : Impedance of arm (right) :

chr11:67,339,278-70,179,848

Best TWAS P=6.85e-11 · Best GWAS P=3.44e-13 conditioned to 4.14e-12

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta ORAOV1 0.13 0.07 lasso 3 0.04 2.0e-03 -4.81 -5.5 3.6e-08 -0.10 0.14 0.44 TRUE
2 GTEx Breast Mammary Tissue IGHMBP2 0.49 0.47 enet 28 0.50 8.1e-29 -4.46 -5.4 5.5e-08 -0.23 1.00 0.00 FALSE
3 GTEx Esophagus Muscularis IGHMBP2 0.12 0.06 enet 17 0.06 9.4e-05 -4.53 -5.2 1.5e-07 -0.34 0.68 0.22 TRUE
4 GTEx Heart Atrial Appendage IGHMBP2 0.26 0.27 lasso 4 0.26 3.9e-12 -5.12 -5.2 1.6e-07 -0.19 1.00 0.00 TRUE
5 GTEx Nerve Tibial IGHMBP2 0.45 0.47 enet 44 0.48 2.0e-38 -4.46 -5.3 1.0e-07 -0.25 1.00 0.00 FALSE
6 GTEx Vagina C11orf24 0.24 0.04 lasso 9 0.08 5.8e-03 0.14 -5.1 2.6e-07 -0.65 0.04 0.50 FALSE
7 ROSMAP Brain Pre-frontal Cortex PPP6R3 0.04 0.01 blup 421 0.02 3.2e-04 7.24 -5.6 1.7e-08 -0.86 0.03 0.97 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SAPS3 0.04 0.02 blup 84 0.04 2.5e-05 5.93 -6.5 6.8e-11 -0.86 0.12 0.87 TRUE