TWAS
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Models
Genes
Traits
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Traits
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Impedance of arm (right)
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chr11:85,456,242-87,349,407
Best TWAS P=1.42e-08 · Best GWAS P=3.24e-09 conditioned to 0.000268
85.5M
86M
86.5M
87M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
GTEx
Thyroid
PRSS23
0.18
0.09
lasso
9
0.14
1.2e-10
-3.9
-5.7
1.4e-08
-0.48
0.58
0.41
TRUE
2
GTEx
Artery Tibial
ME3
0.24
0.06
lasso
8
0.11
4.1e-09
-3.2
5.6
1.7e-08
0.31
0.04
0.95
FALSE
1
CommonMind
Brain Pre-frontal Cortex
PRSS23
0.14
0.13
lasso
8
0.13
4.7e-16
-3.7
-5.2
1.7e-07
-0.62
0.97
0.03
FALSE