Best TWAS P=1.42e-08 · Best GWAS P=3.24e-09 conditioned to 0.000268
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PRSS23 | 0.14 | 0.13 | lasso | 8 | 0.13 | 4.7e-16 | -3.7 | -5.2 | 1.7e-07 | -0.62 | 0.97 | 0.03 | FALSE |
| 2 | GTEx | Artery Tibial | ME3 | 0.24 | 0.06 | lasso | 8 | 0.11 | 4.1e-09 | -3.2 | 5.6 | 1.7e-08 | 0.31 | 0.04 | 0.95 | FALSE |
| 3 | GTEx | Thyroid | PRSS23 | 0.18 | 0.09 | lasso | 9 | 0.14 | 1.2e-10 | -3.9 | -5.7 | 1.4e-08 | -0.48 | 0.58 | 0.41 | TRUE |