Best TWAS P=2.2e-19 · Best GWAS P=1.44e-17 conditioned to 0.333
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | SLC38A2 | 0.02 | 0.02 | blup | 341 | 0.01 | 0.00581 | 7.7 | -7.2 | 4.2e-13 | -0.87 | 0.06 | 0.88 | FALSE |
2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SLC38A2 | 0.10 | 0.06 | blup | 30 | 0.05 | 0.00083 | 8.5 | -9.0 | 2.2e-19 | -0.90 | 0.01 | 0.92 | TRUE |
3 | The Cancer Genome Atlas | Soft Tissue Sarcoma | SLC38A2 | 0.06 | 0.01 | blup | 30 | 0.03 | 0.00513 | 8.5 | -6.7 | 2.2e-11 | -0.93 | 0.01 | 0.76 | FALSE |