[Hub]/) : Traits : Impedance of arm (right) : ← →

chr12:41,777,144-43,541,249

Best TWAS P=3.14e-10 · Best GWAS P=3.86e-08 conditioned to 0.0818

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PPHLN1 0.11 0.11 enet 12 0.13 8.5e-11 5.3 -6.3 3.1e-10 0.67 0.02 0.98 TRUE
2 GTEx Artery Tibial PPHLN1 0.12 0.07 lasso 5 0.09 2.3e-07 -4.6 -5.3 1.2e-07 0.92 0.10 0.90 FALSE
3 GTEx Cells Transformed fibroblasts PPHLN1 0.17 0.10 enet 24 0.17 1.3e-12 -4.3 -6.1 9.2e-10 0.88 0.06 0.93 FALSE
4 GTEx Cells Transformed fibroblasts ZCRB1 0.09 0.03 enet 18 0.08 2.4e-06 -4.6 -5.1 2.8e-07 0.66 0.28 0.53 FALSE
5 GTEx Colon Sigmoid ZCRB1 0.13 0.15 lasso 3 0.12 7.0e-05 5.0 -5.3 9.2e-08 0.68 0.04 0.95 FALSE
6 GTEx Esophagus Muscularis ZCRB1 0.13 0.10 lasso 2 0.08 2.4e-05 -5.3 -5.6 2.1e-08 0.97 0.01 0.99 FALSE
7 GTEx Lung ZCRB1 0.10 0.14 enet 13 0.13 5.6e-10 -5.3 -5.5 4.5e-08 0.95 0.01 0.99 FALSE
8 GTEx Muscle Skeletal ZCRB1 0.05 0.09 lasso 1 0.06 6.0e-07 5.1 -5.1 2.7e-07 0.68 0.03 0.97 FALSE
9 GTEx Thyroid GXYLT1 0.11 0.09 enet 20 0.12 2.8e-09 -3.1 -5.4 7.4e-08 0.69 0.83 0.13 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma ZCRB1 0.04 0.01 blup 34 0.01 1.8e-02 -4.1 -5.4 8.3e-08 0.93 0.01 0.52 FALSE
11 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma PPHLN1 0.11 0.08 blup 109 0.07 1.3e-03 5.3 -5.2 2.1e-07 0.44 0.03 0.85 FALSE